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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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Climate-Induced Changes in Grapevine Yield and Must Sugar Content in Franconia (Germany) between 1805 and 2010

Anna Bock, Tim H. Sparks, Nicole Estrella, Annette Menzel

Corneal Endothelial Expansion Promoted by Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium

Makiko Nakahara, Naoki Okumura, EunDuck P. Kay, Michio Hagiya, Kiwamu Imagawa, Yuuki Hosoda, Shigeru Kinoshita, Noriko Koizumi

Activation of Wnt/β-Catenin Pathway in Monocytes Derived from Chronic Kidney Disease Patients

Heevy Abdulkareem Musa Al-Chaqmaqchi, Ali Moshfegh, Elham Dadfar, Josefin Paulsson, Moustapha Hassan, Stefan H. Jacobson, Joachim Lundahl

Chiral Hydroxylation at the Mononuclear Nonheme Fe(II) Center of 4-(S) Hydroxymandelate Synthase – A Structure-Activity Relationship Analysis

Cristiana M. L. Di Giuro, Cornelia Konstantinovics, Uwe Rinner, Christina Nowikow, Erich Leitner, Grit D. Straganz

Low-Intensity Pulsed Ultrasound Accelerates Tooth Movement via Activation of the BMP-2 Signaling Pathway

Hui Xue, Jun Zheng, Ziping Cui, Xiufeng Bai, Gang Li, Caidi Zhang, Sanhu He, Weihong Li, Shayanne A. Lajud, Yinzhong Duan, Hong Zhou

Pro-Inflammatory Flagellin Proteins of Prevalent Motile Commensal Bacteria Are Variably Abundant in the Intestinal Microbiome of Elderly Humans

B. Anne Neville, Paul O. Sheridan, Hugh M. B. Harris, Simone Coughlan, Harry J. Flint, Sylvia H. Duncan, Ian B. Jeffery, Marcus J. Claesson, R. Paul Ross, Karen P. Scott, Paul W. O'Toole

Quantifying Biomass Changes of Single CD8+ T Cells during Antigen Specific Cytotoxicity

Thomas A. Zangle, Daina Burnes, Colleen Mathis, Owen N. Witte, Michael A. Teitell

Cemented versus Uncemented Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients: A Meta-Analysis

Tao Li, Qianyu Zhuang, Xisheng Weng, Lei Zhou, Yanyan Bian

Downregulation of SPARC Expression Inhibits the Invasion of Human Trophoblast Cells In Vitro

Yahong Jiang, Yan Zhu, Yan Shi, Yaping He, Zhichao Kuang, Zhaogui Sun, Jian Wang

Estimating Effective Population Size from Linkage Disequilibrium between Unlinked Loci: Theory and Application to Fruit Fly Outbreak Populations

John A Sved, Emilie C. Cameron, A. Stuart Gilchrist

Elimination of Metastatic Melanoma Using Gold Nanoshell-Enabled Photothermal Therapy and Adoptive T Cell Transfer

Adham S. Bear, Laura C. Kennedy, Joseph K. Young, Serena K. Perna, Joao Paulo Mattos Almeida, Adam Y. Lin, Phillip C. Eckels, Rebekah A. Drezek, Aaron E. Foster

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts

James J. Cray, Kameron Khaksarfard, Seth M. Weinberg, Mohammed Elsalanty, Jack C. Yu

An Acetylcholinesterase Antibody-Based Quartz Crystal Microbalance for the Rapid Identification of Spinal Ventral and Dorsal Roots

Tao Sui, Yingbin Ge, Wujun Liu, Zongbao K. Zhao, Ning Zhang, Xiaojian Cao

Effects of MICA Expression on the Prognosis of Advanced Non-Small Cell Lung Cancer and the Efficacy of CIK Therapy

Yu Chen, Gen Lin, Zeng-qing Guo, Zhi-feng Zhou, Zhi-yong He, Yun-bin Ye

Tumor Site- and Stage-Specific Associations between Allelic Variants of Glutathione S-Transferase and DNA-Repair Genes and Overall Survival in Colorectal Cancer Patients Receiving 5-Fluorouracil-Based Chemotherapy

Ching-Yu Lai, Ling-Ling Hsieh, Fung-Chang Sung, Reiping Tang, Chyi-Huey Bai, Fang-Yang Wu, Hung-Yi Chiou, Chih-Ching Yeh

Transcriptomic and Physiological Variations of Three Arabidopsis Ecotypes in Response to Salt Stress

Yanping Wang, Li Yang, Zhimin Zheng, Rebecca Grumet, Wayne Loescher, Jian-Kang Zhu, Pingfang Yang, Yuanlei Hu, Zhulong Chan

Unique Gene Expression and MR T2 Relaxometry Patterns Define Chronic Murine Dextran Sodium Sulphate Colitis as a Model for Connective Tissue Changes in Human Crohn’s Disease

Christine Breynaert, Tom Dresselaers, Clémentine Perrier, Ingrid Arijs, Jonathan Cremer, Leentje Van Lommel, Kristel Van Steen, Marc Ferrante, Frans Schuit, Séverine Vermeire, Paul Rutgeerts, Uwe Himmelreich, Jan L. Ceuppens, Karel Geboes, Gert Van Assche

The Effect of Hypothermia Therapy on Cortical Laminar Disruption following Ischemic Injury in Neonatal Mice

Hiroyuki Kida, Sadahiro Nomura, Mizuya Shinoyama, Makoto Ideguchi, Yuji Owada, Michiyasu Suzuki

Dissociation between AKAP3 and PKARII Promotes AKAP3 Degradation in Sperm Capacitation

Pnina Hillman, Debby Ickowicz, Ruth Vizel, Haim Breitbart

Mechanisms and Fitness Costs of Resistance to Antimicrobial Peptides LL-37, CNY100HL and Wheat Germ Histones

Hava Lofton, Maria Pr？nting, Elisabeth Thulin, Dan I. Andersson

Glucose Metabolism during Resting State Reveals Abnormal Brain Networks Organization in the Alzheimer’s Disease and Mild Cognitive Impairment

Gretel Sanabria-Diaz, Eduardo Martínez-Montes, Lester Melie-Garcia, the Alzheimer’s Disease Neuroimaging Initiative

Optimization of a Widefield Structured Illumination Microscope for Non-Destructive Assessment and Quantification of Nuclear Features in Tumor Margins of a Primary Mouse Model of Sarcoma

Henry L. Fu, Jenna L. Mueller, Melodi P. Javid, Jeffrey K. Mito, David G. Kirsch, Nimmi Ramanujam, J. Quincy Brown

What Took Them So Long? Explaining PhD Delays among Doctoral Candidates

Rens van de Schoot, Mara A. Yerkes, Jolien M. Mouw, Hans Sonneveld

Evidence That Personal Genome Testing Enhances Student Learning in a Course on Genomics and Personalized Medicine

Keyan Salari, Konrad J. Karczewski, Louanne Hudgins, Kelly E. Ormond

Using Complete Genome Comparisons to Identify Sequences Whose Presence Accurately Predicts Clinically Important Phenotypes

Barry G. Hall, Heliodoro Cardenas, Miriam Barlow

Identification and Mapping of Linear Antibody Epitopes in Human Serum Albumin Using High-Density Peptide Arrays

Lajla Bruntse Hansen, Soren Buus, Claus Schafer-Nielsen

An Empirical Approach towards the Efficient and Optimal Production of Influenza-Neutralizing Ovine Polyclonal Antibodies Demonstrates That the Novel Adjuvant CoVaccine HT？ Is Functionally Superior to Freund's Adjuvant

Natalie E. Stevens, Cara K. Fraser, Mohammed Alsharifi, Michael P. Brown, Kerrilyn R. Diener, John D. Hayball

The Relationship between Diver Experience Levels and Perceptions of Attractiveness of Artificial Reefs - Examination of a Potential Management Tool

Anne E. Kirkbride-Smith, Philip M. Wheeler, Magnus L. Johnson

A Machine Learning Method for the Prediction of Receptor Activation in the Simulation of Synapses

Jesus Montes, Elena Gomez, Angel Merchán-Pérez, Javier DeFelipe, Jose-Maria Pe？a

Recombinant Human Sonic Hedgehog Protein Regulates the Expression of ZO-1 and Occludin by Activating Angiopoietin-1 in Stroke Damage

Yuan-peng Xia, Quan-wei He, Ya-nan Li, Sheng-cai Chen, Ming Huang, Yong Wang, Yuan Gao, Yan Huang, Meng-die Wang, Ling Mao, Bo Hu

Molecular Cloning and Characterization of a Surface-Localized Adhesion Protein in Mycoplasma bovis Hubei-1 Strain

Xiaohui Zou, Yuan Li, Yang Wang, Yumei Zhou, Yang Liu, Jiuqing Xin

Toward Repurposing Ciclopirox as an Antibiotic against Drug-Resistant Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae

Kimberly M. Carlson-Banning, Andrew Chou, Zhen Liu, Richard J. Hamill, Yongcheng Song, Lynn Zechiedrich

A Mouse Model for Candida glabrata Hematogenous Disseminated Infection Starting from the Gut: Evaluation of Strains with Different Adhesion Properties

Ralitsa Atanasova, Adela Angoulvant, Maurel Tefit, Frédérick Gay, Juliette Guitard, Dominique Mazier, Cécile Fairhead, Christophe Hennequin

GobyWeb: Simplified Management and Analysis of Gene Expression and DNA Methylation Sequencing Data

Kevin C. Dorff, Nyasha Chambwe, Zachary Zeno, Manuele Simi, Rita Shaknovich, Fabien Campagne

Characterization of Cell Subpopulations Expressing Progenitor Cell Markers in Porcine Cardiac Valves

Huan Wang, Balaji Sridhar, Leslie A. Leinwand, Kristi S. Anseth

Roflumilast Inhibits Respiratory Syncytial Virus Infection in Human Differentiated Bronchial Epithelial Cells

Manuel Mata, Isidoro Martinez, Jose A. Melero, Herman Tenor, Julio Cortijo

Family and Neighbourhood Socioeconomic Inequalities in Childhood Trajectories of BMI and Overweight: Longitudinal Study of Australian Children

Pauline W. Jansen, Fiona K. Mensah, Jan M. Nicholson, Melissa Wake

A New Omics Data Resource of Pleurocybella porrigens for Gene Discovery

Tomohiro Suzuki, Kaori Igarashi, Hideo Dohra, Takumi Someya, Tomoyuki Takano, Kiyonori Harada, Saori Omae, Hirofumi Hirai, Kentaro Yano, Hirokazu Kawagishi

Effects of Mild Cold Shock (25°C) Followed by Warming Up at 37°C on the Cellular Stress Response

Thibaut Neutelings, Charles A. Lambert, Betty V. Nusgens, Alain C. Colige

Challenges in Using Cultured Primary Rodent Hepatocytes or Cell Lines to Study Hepatic HDL Receptor SR-BI Regulation by Its Cytoplasmic Adaptor PDZK1

Kosuke Tsukamoto, Lorenna Buck, Walker Inman, Linda Griffith, Olivier Kocher, Monty Krieger

Unit Cost of Medical Services at Different Hospitals in India

Susmita Chatterjee, Carol Levin, Ramanan Laxminarayan

Polymorphisms in DNA-Repair Genes in a Cohort of Prostate Cancer Patients from Different Areas in Spain: Heterogeneity between Populations as a Confounding Factor in Association Studies

Luis Alberto Henríquez-Hernández, Almudena Valenciano, Palmira Foro-Arnalot, María Jesús álvarez-Cubero, José Manuel Cozar, José Francisco Suárez-Novo, Manel Castells-Esteve, Adriana Ayala-Gil, Pablo Fernández-Gonzalo, Montse Ferrer, Ferrán Guedea, Gemma Sancho-Pardo, Jordi Craven-Bartle, María José Ortiz-Gordillo, Patricia Cabrera-Roldán, Estefanía Herrera-Ramos, Pedro C. Lara

Rotigotine Transdermal Patch in Parkinson’s Disease: A Systematic Review and Meta-Analysis

Chang-Qing Zhou, Shan-Shan Li, Zhong-Mei Chen, Feng-Qun Li, Peng Lei, Guo-Guang Peng

BMP9 Is a Proliferative and Survival Factor for Human Hepatocellular Carcinoma Cells

Blanca Herrera, María García-álvaro, Silvia Cruz, Peter Walsh, Margarita Fernández, Cesáreo Roncero, Isabel Fabregat, Aránzazu Sánchez, Gareth J. Inman

Effects of Inhibition of Serine Palmitoyltransferase (SPT) and Sphingosine Kinase 1 (SphK1) on Palmitate Induced Insulin Resistance in L6 Myotubes

Agnieszka Mik？osz, Bart？omiej ？ukaszuk, Marcin Baranowski, Jan Górski, Adrian Chabowski

Chronic Hydrocephalus after Experimental Subarachnoid Hemorrhage

Peter Lackner, Alexander Vahmjanin, Qin Hu, Paul R. Krafft, William Rolland, John H. Zhang

Derivatives of the Antimicrobial Peptide BP100 for Expression in Plant Systems

Esther Badosa, Gemma Moiset, Laura Montesinos, Montserrat Talleda, Eduard Bardají, Lidia Feliu, Marta Planas, Emilio Montesinos

IL-10 Gene Polymorphisms and Susceptibility to Systemic Lupus Erythematosus: A Meta-Analysis

Ping Liu, Jianwen Song, Hui Su, Linli Li, Ning Lu, Rongli Yang, Zhenhui Peng

Patterned-String Tasks: Relation between Fine Motor Skills and Visual-Spatial Abilities in Parrots

Anastasia Krasheninnikova

A Mouse Model of Familial ALS Has Increased CNS Levels of Endogenous Ubiquinol9/10 and Does Not Benefit from Exogenous Administration of Ubiquinol10

Jacopo Lucchetti, Marianna Marino, Simonetta Papa, Massimo Tortarolo, Giovanna Guiso, Silvia Pozzi, Valentina Bonetto, Silvio Caccia, Ettore Beghi, Caterina Bendotti, Marco Gobbi

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