Total of 356 articles.


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May 19, 2023Open    AccessArticle

What it Takes to Inspire: A comparative Role Model Analysis of Students in Entrepreneurship and Teaching

Anh Dinh,Diana Püplichhuysen
According to career education and learning research, role models can significantly influence others’ decision-making processes and career choices. Such effects may be particularly relevant for potential entrepreneurs and future teachers, as much learning in these professions relies heavily on role models. Thus, educating students who desire to work in these fields might profit from a more role model-centered approach. However, research has shown that university educators rarely serve as role mod...

Entrepreneurship 
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May 19, 2023Open    AccessArticle

EL COMERCIO SOCIAL EN TIEMPOS DE CRISIS: EL CASO DE CONSUMELOCAL.ME

Marcos Pérez Mendoza
The trade or exchange of products has changed from the face-to-face format to a virtual one. Commerce then starts from a traditional environment to a virtual environment in the face of the growing impact of the internet, giving space to electronic commerce. Derived from the COVID-19 pandemic, face-to-face purchases were limited due to confinement, special days and hours, thereby causing an economic crisis throughout the globe. The MSMEs in search of virtual means to advertise th...

Supply Chain Management  Strategic Management Policy  Business Theories  Behavioral Economics  Sociology  Project Management and Strategy  Project Management  Economics  Tourism Economy  Business Management  Culture  Public Administration  Business Ethics and Corporate Social Responsibility  Management Organization  Socioeconomics  Educational Economy and Management  Business Communication  Business Analysis  Corporate Governance  Accounting 

May 19, 2023Open    AccessArticle

Effect of non-thermal atmospheric pressure plasma on MDA-MB-231 breast cancer cells

Ramin Mehrabifard, Hassan Mehdian, Mahdi Bakhshzadmahmoudi
Cold atmospheric plasma (CAP) has received great attention due to its noteworthy ability, and has also been widely studied over few decades in physics, biology and medicine. The purpose of this study is to evaluate the cold atmospheric pressure plasma effects on the proliferation of breast cancer cells. MDAMB-231 was used for this experiment. MDA-MB-231 cells were cultured in 24-well plate and treated with non-thermal plasma. The viability of the cancer cells was determined by MTT assay. Differe...

Plasma  Cell Biology 

May 19, 2023Open    AccessArticle

Video Capsule Endoscopy and Ingestible Electronics: Emerging Trends in Sensors, Circuits, Materials, Telemetry, Optics, and Rapid Reading Software

Dylan Miley, Leonardo Bertoncello Machado, Calvin Condo, Albert E. Jergens, Kyoung-Jin Yoon, Santosh Pandey
Real-time monitoring of the gastrointestinal tract in a safe and comfortable manner is valuable for the diagnosis and therapy of many diseases. Within this realm, our review captures the trends in ingestible capsule systems with a focus on hardware and software technologies used for capsule endoscopy and remote patient monitoring. We introduce the structure and functions of the gastrointestinal tract, and the FDA guidelines for ingestible wireless telemetric medical devices. We survey the advanc...

Electric Engineering  Drugs & Devices  Genetic Engineering  Biological Engineering  Evidence Based Medicine  Chemical Engineering & Technology  Gastroenterology & Hepatology  Diagnostics 

May 19, 2023Open    AccessArticle

Unidirectional, electrotactic-response valve for Caenorhabditis elegans in microfluidic devices

Santosh Pandey
We report a nematode electrotactic-response valve (NERV) to control the locomotion of Caenorhabditis elegans (C. elegans) in microfluidic devices. This nonmechanical, unidirectional valve is based on creating a confined region of lateral electric field that is switchable and reversible. We observed that C. elegans do not prefer to pass through this region if the field lines are incident to its forward movement. Upon reaching the boundary of the NERV, the incident worms partially penetrate the fi...

Animal Behavior  Zoology  Mathematical Biology  Veterinary Medicine  Cell Biology  Parasitology  Developmental Biology  Evolutionary Studies  Bioengineering  Bioinformatics  Environmental Sciences  Biophysics 

May 19, 2023Open    AccessArticle

Characterization of a MEMS BioChip for planar patch-clamp recording

Santosh Pandey, Mehrotra, R. Wykosky, S. White, M.H.
We describe a planar MEMS silicon structure to record ion channel currents in biological cells. The conventional method of performing an electrophysiological experiment, 'patch-clamping', employs a glass micropipette. The micropipette tip is a source of thermal noise because of its inherent, tapered, conical structure, giving rise to a large pipette resistance. This pipette resistance, when coupled with the biological cell capacitance, limits the available bandwidth of single ion channel recordi...

Taxonomy  Microbiology  Biochemistry  Biodiversity  Developmental Biology  Bioengineering  Bioinformatics  Environmental Sciences  Agricultural Science  Computational Biology  Genetics  Cell Biology  Food Science & Technology  Parasitology  Synthetic Biology 

May 19, 2023Open    AccessArticle

Simulation of biological ion channels with technology computer-aided design

Santosh Pandey, Bortei-Doku, A. White, M.H.
Computer simulations of realistic ion channel structures have always been challenging and a subject of rigorous study. Simulations based on continuum electrostatics have proven to be computationally cheap and reasonably accurate in predicting a channel's behavior. In this paper we discuss the use of a device simulator, SILVACO, to build a solid-state model for KcsA channel and study its steady-state response. SILVACO is a well-established program, typically used by electrical engineers to simula...

Biological Chemistry  Photochemistry  Taxonomy  Medicinal Chemistry  Ecosystem Science  Developmental Biology  Computational Robotics  Complex network models  Artificial Intelligence  Genetics  Theoretical Chemistry  Analytical Chemistry  Neuroscience  Biological Materials  Nanometer Materials  Green Chemistry  Mathematical Biology  Molecular Biology  Microbiology  Biochemistry  Biodiversity  Bioengineering  Bioinformatics  Biophysics  Biotechnology  Functional Materials  Computational Biology  Synthetic Biology 

May 19, 2023Open    AccessArticle

Effective drug combination for Caenorhabditis elegans nematodes discovered by output-driven feedback system control technique

Ding, X. Njus, Z. Kong, T. Su, W. Ho, C.-M. Pandey, S.
Infections from parasitic nematodes (or roundworms) contribute to a significant disease burden and productivity losses for humans and livestock. The limited number of anthelmintics (or antinematode drugs) available today to treat these infections are rapidly losing their efficacy as multidrug resistance in parasites becomes a global health challenge. We propose an engineering approach to discover an anthelmintic drug combination that is more potent at killing wild-type Caenorhabditis elegans wor...

Neuroscience  Marine Biology  Toxicology  Taxonomy  Microbiology  Ecosystem Science  Biodiversity  Developmental Biology  Bioengineering  Environmental Sciences  Animal Behavior  Agricultural Science  Biotechnology  Computational Biology  Food Science & Technology  Parasitology  Plant Science  Synthetic Biology 

May 19, 2023Open    AccessArticle

Amplitude modulated sinusoidal microchannels for observing adaptability in C. elegans locomotion

Parashar, A. Lycke, R. Carr, J.A. Pandey, Santosh
In this paper, we present a movement-based assay to observe adaptability in Caenorhabditis elegans locomotion behavior. The assay comprises a series of sinusoidal microchannels with a fixed wavelength and modulating (increasing or decreasing) amplitude. The channel width is comparable to the body diameter of the organism. Worms are allowed to enter the channel from the input port and migrate toward the output port. Within channel sections that closely match the worm's natural undulations, the wo...

Animal Behavior  Agricultural Science  Veterinary Medicine  Parasitology  Plant Science  Soil Science  Biodiversity  Bioengineering 

May 19, 2023Open    AccessArticle

Flexible and disposable paper- and plastic based gel micropads for nematode handling, imaging, and chemical testing

Njus, Zach Kong, Taejoon Kalwa, Upender Legner, Christopher Weinstein, Matthew Flanigan, Shawn Saldanha, Jenifer Pandey, Santosh
In this paper, we explore the use of microfluidic paper-based analytical devices (?PADs) to study the behavior of Caenorhabditis elegans. We show how these devices can be fabricated on paper and plastic substrates, as well as how to load, visualize, and transfer single and multiple nematodes. We also demonstrate the use of anthelmintic drug, levamisole, to perform chemical testing on C. elegans. Furthermore, we provide a custom program that is able to recognize individual worms on the ?PADs in r...

Animal Behavior  Computational Biology  Microbiology  Cell Biology  Parasitology  Plant Science  Soil Science  Developmental Biology  Bioengineering  Environmental Sciences  Biophysics 

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