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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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The Role of Decision Support System (DSS) in Prevention of Cardiovascular Disease: A Systematic Review and Meta-Analysis

Raghupathy Anchala, Maria P. Pinto, Amir Shroufi, Rajiv Chowdhury, Jean Sanderson, Laura Johnson, Patricia Blanco, Dorairaj Prabhakaran, Oscar H. Franco

Paralogous ALT1 and ALT2 Retention and Diversification Have Generated Catalytically Active and Inactive Aminotransferases in Saccharomyces cerevisiae

Georgina Pe？alosa-Ruiz, Cristina Aranda, Laura Ongay-Larios, Maritrini Colon, Hector Quezada, Alicia Gonzalez

Estimating Coextinction Risks from Epidemic Tree Death: Affiliate Lichen Communities among Diseased Host Tree Populations of Fraxinus excelsior

Mari T. J？nsson, G？ran Thor

Evidence for Phenotypic Plasticity in Aggressive Triple-Negative Breast Cancer: Human Biology Is Recapitulated by a Novel Model System

Nicholas C. D’Amato, Julie H. Ostrander, Michelle L. Bowie, Christopher Sistrunk, Alexander Borowsky, Robert D. Cardiff, Katie Bell, Lawrence J. T. Young, Karl Simin, Robin E. Bachelder, Jeff Delrow, Alyssa Dawson, Lisa D. Yee, Krzysztof Mrózek, Timothy M. Clay, Takuya Osada, Victoria L. Seewaldt

Peripheral Nervous System Neuropathology and Progressive Sensory Impairments in a Mouse Model of Mucopolysaccharidosis IIIB

Haiyan Fu, Julianne D. Bartz, Robert L. Stephens, Douglas M. McCarty

Met Kinetic Signature Derived from the Response to HGF/SF in a Cellular Model Predicts Breast Cancer Patient Survival

Gideon Y. Stein, Nir Yosef, Hadar Reichman, Judith Horev, Adi Laser-Azogui, Angelique Berens, James Resau, Eytan Ruppin, Roded Sharan, Ilan Tsarfaty

IL-27-Induced Gene Expression Is Downregulated in HIV-Infected Subjects

Christina Guzzo, Wilma M. Hopman, Nor Fazila Che Mat, Wendy Wobeser, Katrina Gee

Neuronal Mechanisms of Voice Control Are Affected by Implicit Expectancy of Externally Triggered Perturbations in Auditory Feedback

Oleg Korzyukov, Lindsey Sattler, Roozbeh Behroozmand, Charles R. Larson

Pharmacological Inhibition of Microsomal Prostaglandin E Synthase-1 Suppresses Epidermal Growth Factor Receptor-Mediated Tumor Growth and Angiogenesis

Federica Finetti, Erika Terzuoli, Elena Bocci, Isabella Coletta, Lorenzo Polenzani, Giorgina Mangano, Maria Alessandra Alisi, Nicola Cazzolla, Antonio Giachetti, Marina Ziche, Sandra Donnini

Novel Characterization of Lymphatic Valve Formation during Corneal Inflammation

Tan Truong,Eda Altiok,Don Yuen,Tatiana Ecoiffier,Lu Chen

Development of TaqMan Probe-Based Insulated Isothermal PCR (iiPCR) for Sensitive and Specific On-Site Pathogen Detection

Yun-Long Tsai, Hwa-Tang Thomas Wang, Hsiao-Fen Grace Chang, Chuan-Fu Tsai, Ching-Ko Lin, Ping-Hua Teng, Chen Su, Chien-Chung Jeng, Pei-Yu Lee

Frog Oocytes to Unveil the Structure and Supramolecular Organization of Human Transport Proteins

Marc J. Bergeron,Rajendra Boggavarapu,Marcel Meury,Z？hre Ucurum,Luc Caron,Paul Isenring,Matthias A. Hediger,Dimitrios Fotiadis

Scalable Transcriptome Preparation for Massive Parallel Sequencing

Henrik Stranneheim,Beata Werne,Ellen Sherwood,Joakim Lundeberg

Assessment of Strain-Specific PrPSc Elongation Rates Revealed a Transformation of PrPSc Properties during Protein Misfolding Cyclic Amplification

Nuria Gonzalez-Montalban, Ilia V. Baskakov

The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity

Paola Larghi, Chiara Porta, Elena Riboldi, Maria Grazia Totaro, Lorenzo Carraro, Ciriana Orabona, Antonio Sica

Seroepidemiology of Bovine Viral Diarrhoea Virus (BVDV) in the Adamawa Region of Cameroon and Use of the SPOT Test to Identify Herds with PI Calves

Ian G. Handel,Kim Willoughby,Fiona Land,Bronwyn Koterwas,Kenton L. Morgan,Vincent N. Tanya,Barend M. deC. Bronsvoort

Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival

Jatinder K. Juss, Richard P. Hayhoe, Charles E. Owen, Ian Bruce, Sarah R. Walmsley, Andrew S. Cowburn, Suhasini Kulkarni, Keith B. Boyle, Len Stephens, Phillip T. Hawkins, Edwin R. Chilvers, Alison M. Condliffe

Microenvironmental Influence on Pre-Clinical Activity of Polo-Like Kinase Inhibition in Multiple Myeloma: Implications for Clinical Translation

Douglas W. McMillin,Jake Delmore,Joseph Negri,Melissa Ooi,Steffen Klippel,Chandrasekhar V. Miduturu,Nathanael S. Gray,Paul G. Richardson,Kenneth C. Anderson,Andrew L. Kung,Constantine S. Mitsiades

Stage-Related Alterations in Renal Cell Carcinoma – Comprehensive Quantitative Analysis by 2D-DIGE and Protein Network Analysis

Heike Junker,Simone Venz,Uwe Zimmermann,Andrea Thiele,Christian Scharf,Reinhard Walther

Expressions of Multiple Neuronal Dynamics during Sensorimotor Learning in the Motor Cortex of Behaving Monkeys

Yael Mandelblat-Cerf,Itai Novick,Eilon Vaadia

Membrane Bridging and Hemifusion by Denaturated Munc18

Yi Xu,Alpay B. Seven,Lijing Su,Qiu-Xing Jiang,Josep Rizo

Live Attenuated S. Typhimurium Vaccine with Improved Safety in Immuno-Compromised Mice

Balamurugan Periaswamy, Lisa Maier, Vikalp Vishwakarma, Emma Slack, Marcus Kremer, Helene L. Andrews-Polymenis, Michael McClelland, Andrew J. Grant, Mrutyunjay Suar, Wolf-Dietrich Hardt

Reduced Fractional Anisotropy of Corpus Callosum Modulates Inter-Hemispheric Resting State Functional Connectivity in Migraine Patients without Aura

Kai Yuan, Wei Qin, Peng Liu, Ling Zhao, Dahua Yu, Limei Zhao, Minghao Dong, Jixin Liu, Xuejuan Yang, Karen M. von Deneen, Fanrong Liang, Jie Tian

Generation of Corneal Epithelial Cells from Induced Pluripotent Stem Cells Derived from Human Dermal Fibroblast and Corneal Limbal Epithelium

Ryuhei Hayashi, Yuki Ishikawa, Miyuki Ito, Tomofumi Kageyama, Kuniko Takashiba, Tsuyoshi Fujioka, Motokazu Tsujikawa, Hiroyuki Miyoshi, Masayuki Yamato, Yukio Nakamura, Kohji Nishida

The miR-17 Family Links p63 Protein to MAPK Signaling to Promote the Onset of Human Keratinocyte Differentiation

Ning Wu, Eric Sulpice, Patricia Obeid, Sami Benzina, Frédérique Kermarrec, Stéphanie Combe, Xavier Gidrol

A Least Angle Regression Model for the Prediction of Canonical and Non-Canonical miRNA-mRNA Interactions

Julia C. Engelmann, Rainer Spang

HPV Genotyping and Site of Viral Integration in Cervical Cancers in Indian Women

Poulami Das, Asha Thomas, Umesh Mahantshetty, Shyam K. Shrivastava, Kedar Deodhar, Rita Mulherkar

Self-Organization Leads to Supraoptimal Performance in Public Transportation Systems

Carlos Gershenson

Flare, Persistently Active Disease, and Serologically Active Clinically Quiescent Disease in Systemic Lupus Erythematosus: A 2-Year Follow-Up Study

Fabrizio Conti, Fulvia Ceccarelli, Carlo Perricone, Francesca Miranda, Simona Truglia, Laura Massaro, Viviana Antonella Pacucci, Virginia Conti, Izabella Bartosiewicz, Francesca Romana Spinelli, Cristiano Alessandri, Guido Valesini

APC/CCdh1 Targets Brain-Specific Kinase 2 (BRSK2) for Degradation via the Ubiquitin-Proteasome Pathway

Ruwei Li, Bo Wan, Jun Zhou, Yingli Wang, Ting Luo, Xiuting Gu, Fang Chen, Long Yu

Predicting Metabolic Pathways of Small Molecules and Enzymes Based on Interaction Information of Chemicals and Proteins

Yu-Fei Gao, Lei Chen, Yu-Dong Cai, Kai-Yan Feng, Tao Huang, Yang Jiang

Structural Design Principles of Complex Bird Songs: A Network-Based Approach

Kazutoshi Sasahara, Martin L. Cody, David Cohen, Charles E. Taylor

The Role of Activity in Synaptic Degeneration in a Protein Misfolding Disease, Prion Disease

Matteo Caleo, Laura Restani, Eleonora Vannini, Zuzana Siskova, Hussain Al-Malki, Ruth Morgan, Vincent O'Connor, V. Hugh Perry

Promotion of Spinal Cord Regeneration by Neural Stem Cell-Secreted Trimerized Cell Adhesion Molecule L1

Xiaowen He, Michael Knepper, Cheng Ding, Jun Li, Suita Castro, Maham Siddiqui, Melitta Schachner

A Single-Day Treatment with Mifepristone Is Sufficient to Normalize Chronic Glucocorticoid Induced Suppression of Hippocampal Cell Proliferation

Pu Hu, Charlotte Oomen, Anne-Marie van Dam, Jordi Wester, Jiang-Ning Zhou, Marian Jo？ls, Paul J. Lucassen

Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are Independent Risk Predictors of Short-Term Mortality in Patients with Acute Coronary Syndromes

Saskia C. A. de Jager, Brenda W. C. Bongaerts, Michael Weber, Adriaan O. Kraaijeveld, Mat Rousch, Stefanie Dimmeler, Marja P. van Dieijen-Visser, Kitty B. J. M. Cleutjens, Patty J. Nelemans, Theo J. C. van Berkel, Erik A. L. Biessen

Modeling and Experimental Analyses Reveals Signaling Plasticity in a Bi-Modular Assembly of CD40 Receptor Activated Kinases

Uddipan Sarma, Archana Sareen, Moitrayee Maiti, Vanita Kamat, Raki Sudan, Sushmita Pahari, Neetu Srivastava, Somenath Roy, Sitabhra Sinha, Indira Ghosh, Ajit G. Chande, Robin Mukhopadhyaya, Bhaskar Saha

A Novel Nonsense Mutation in the DMP1 Gene Identified by a Genome-Wide Association Study Is Responsible for Inherited Rickets in Corriedale Sheep

Xia Zhao,Keren E. Dittmer,Hugh T. Blair,Keith G. Thompson,Max F. Rothschild,Dorian J. Garrick

Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

Andre Z. Kyme,Victor W. Zhou,Steven R. Meikle,Clive Baldock,Roger R. Fulton

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis

Tom H. M. Ottenhoff, Ranjeeta Hari Dass, Ninghan Yang, Mingzi M. Zhang, Hazel E. E. Wong, Edhyana Sahiratmadja, Chiea Chuen Khor, Bachti Alisjahbana, Reinout van Crevel, Sangkot Marzuki, Mark Seielstad, Esther van de Vosse, Martin L. Hibberd

Rapid Analysis of Listeria monocytogenes Cell Wall Teichoic Acid Carbohydrates by ESI-MS/MS

Marcel R. Eugster,Martin J. Loessner

Smoking during Pregnancy Is Associated with a Decreased Incidence of Obstetric Anal Sphincter Injuries in Nulliparous Women

Sari R？is？nen, Katri Vehvil？inen-Julkunen, Mika Gissler, Seppo Heinonen

Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions

Jenny Blechingberg, Yonglun Luo, Lars Bolund, Christian Kroun Damgaard, Anders Lade Nielsen

A Bacillus Flagellar Motor That Can Use Both Na+ and K+ as a Coupling Ion Is Converted by a Single Mutation to Use Only Na+

Naoya Terahara, Motohiko Sano, Masahiro Ito

Selecting Biological Meaningful Environmental Dimensions of Low Discrepancy among Ranges to Predict Potential Distribution of Bean Plataspid Invasion

Gengping Zhu, Matthew J. Petersen, Wenjun Bu

Individual and County-Level Factors Associated with Use of Multiple Prescribers and Multiple Pharmacies to Obtain Opioid Prescriptions in California

Huijun Han, Philip H. Kass, Barth L. Wilsey, Chin-Shang Li

IL1 Receptor Antagonist Gene IL1-RN Variable Number of Tandem Repeats Polymorphism and Cancer Risk: A Literature Review and Meta-Analysis

Ying Zhang, Changming Liu, Huiping Peng, Jianzhi Zhang, Quanlin Feng

Population PK/PD Model of Homocysteine Concentrations after High-Dose Methotrexate Treatment in Patients with Acute Lymphoblastic Leukemia

Hauke Rühs, Achim Becker, Anne Drescher, John C. Panetta, Ching-Hon Pui, Mary V. Relling, Ulrich Jaehde

Transcriptional and Non-Transcriptional Functions of PPARβ/δ in Non-Small Cell Lung Cancer

Davide Genini, Ramon Garcia-Escudero, Giuseppina M. Carbone, Carlo V. Catapano

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