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PLOS ONE

ISSN Print: 1932-6203

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Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase

Lu-Sha Cao, Jue Wang, Yuling Chen, Haiteng Deng, Zhi-Xin Wang, Jia-Wei Wu

Acetaldehyde-Derived Advanced Glycation End-Products Promote Alcoholic Liver Disease

Nobuhiko Hayashi, Joseph George, Masayoshi Takeuchi, Atsushi Fukumura, Nobuyuki Toshikuni, Tomiyasu Arisawa, Mikihiro Tsutsumi

Genetic Polymorphism of NOS3 with Susceptibility to Deep Vein Thrombosis after Orthopedic Surgery: A Case-Control Study in Chinese Han Population

Jizheng Qin, Jin Dai, Zhihong Xu, Dongyang Chen, Jianghui Qin, Dongquan Shi, Huajian Teng, Qing Jiang

Predictive Accuracy of 29-Comorbidity Index for In-Hospital Deaths in US Adult Hospitalizations with a Diagnosis of Venous Thromboembolism

James Tsai, Karon Abe, Sheree L. Boulet, Michele G. Beckman, W. Craig Hooper, Althea M. Grant

Nutritional Status of Orphaned and Separated Children and Adolescents Living in Community and Institutional Environments in Uasin Gishu County, Kenya

Paula Braitstein, Samuel Ayaya, Winstone M. Nyandiko, Allan Kamanda, Julius Koech, Peter Gisore, Lukoye Atwoli, Rachel C. Vreeman, Corey Duefield, David O. Ayuku

Imperfect Implementation of an Early Warning Scoring System in a Danish Teaching Hospital: A Cross-Sectional Study

Mark Niegsch, Maria Louise Fabritius, Jacob Anh？j

Modulation of NKG2D Expression in Human CD8+ T Cells Corresponding with Tuberculosis Drug Cure

Syeda S. Hassan, Jang-Eun Cho, Muhammad Akram, Katherine L. Fielding, Hazel M. Dockrell, Jacqueline M. Cliff

Evaluation of Nanoparticle Uptake in Co-culture Cancer Models

Elisabete C. Costa, Vítor M. Gaspar, Jo？o G. Marques, Paula Coutinho, Ilídio J. Correia

Chromosome Painting in Three Species of Buteoninae: A Cytogenetic Signature Reinforces the Monophyly of South American Species

Edivaldo Herculano C. de Oliveira, Marcella Mergulh？o Tagliarini, Michelly S. dos Santos, Patricia C. M. O'Brien, Malcolm A. Ferguson-Smith

Lysine-Specific Demethylase 1 (LSD1/KDM1A) Contributes to Colorectal Tumorigenesis via Activation of the Wnt/Β-Catenin Pathway by Down-Regulating Dickkopf-1 (DKK1)

Zebin Huang, Shangze Li, Wei Song, Xin Li, Qinshan Li, Zeyan Zhang, Yongqing Han, Xiaodong Zhang, Shiying Miao, Runlei Du, Linfang Wang

Low C-Reactive Protein Levels in a Traditional West-African Population Living in a Malaria Endemic Area

Ulrika K. Eriksson, David van Bodegom, Linda May, Anna G. C. Boef, Rudi G. J. Westendorp

SIRT1 is a Direct Coactivator of Thyroid Hormone Receptor β1 with Gene-Specific Actions

Ji Ho Suh, Douglas H. Sieglaff, Aijun Zhang, Xuefeng Xia, Aleksandra Cvoro, Glenn E. Winnier, Paul Webb

Elimination of Aberrant DRG Circuitries in Sema3A Mutant Mice Leads to Extensive Neuronal Deficits

Ayal Ben-Zvi, Sahar Sweetat, Oded Behar

Ursolic Acid Inhibits Adipogenesis in 3T3-L1 Adipocytes through LKB1/AMPK Pathway

Yonghan He, Ying Li, Tiantian Zhao, Yanwen Wang, Changhao Sun

Crosstalk between Shh and TGF-β Signaling in Cyclosporine-Enhanced Cell Proliferation in Human Gingival Fibroblasts

Yi Chung, Earl Fu

Progression of Kidney Disease in Non-Diabetic Patients with Coronary Artery Disease: Predictive Role of Circulating Matrix Metalloproteinase-2, -3, and -9

Ta-Wei Hsu, Ko-Lin Kuo, Szu-Chun Hung, Po-Hsun Huang, Jaw-Wen Chen, Der-Cherng Tarng

Ningaloo Reef: Shallow Marine Habitats Mapped Using a Hyperspectral Sensor

Halina T. Kobryn, Kristin Wouters, Lynnath E. Beckley, Thomas Heege

The Aqueous Extract of Ficus religiosa Induces Cell Cycle Arrest in Human Cervical Cancer Cell Lines SiHa (HPV-16 Positive) and Apoptosis in HeLa (HPV-18 Positive)

Amit S. Choudhari, Snehal A. Suryavanshi, Ruchika Kaul-Ghanekar

Yeast One-Hybrid Gγ Recruitment System for Identification of Protein Lipidation Motifs

Nobuo Fukuda, Motomichi Doi, Shinya Honda

The Microbial Community in the Feces of the White Rhinoceros (Ceratotherium simum) as Determined by Barcoded Pyrosequencing Analysis

Gaorui Bian, Li Ma, Yong Su, Weiyun Zhu

WRINKLED1, A Ubiquitous Regulator in Oil Accumulating Tissues from Arabidopsis Embryos to Oil Palm Mesocarp

Wei Ma, Que Kong, Vincent Arondel, Aruna Kilaru, Philip D. Bates, Nicholas A. Thrower, Christoph Benning, John B. Ohlrogge

DNA Methyltransferase Candidate Polymorphisms, Imprinting Methylation, and Birth Outcome

Paul Haggarty, Gwen Hoad, Graham W. Horgan, Doris M. Campbell

Methadone Maintenance Treatment Participant Retention and Behavioural Effectiveness in China: A Systematic Review and Meta-Analysis

Lei Zhang, Eric P. F. Chow, Xun Zhuang, Yanxian Liang, Yafei Wang, Caiyun Tang, Li Ling, Joseph D. Tucker, David P. Wilson

Cancer-Associated Fibroblasts Promote Proliferation of Endometrial Cancer Cells

Kavita S. Subramaniam, Seng Tian Tham, Zahurin Mohamed, Yin Ling Woo, Noor Azmi Mat Adenan, Ivy Chung

Blood Viscosity and the Expression of Inflammatory and Adhesion Markers in Homozygous Sickle Cell Disease Subjects with Chronic Leg Ulcers

Andre S. Bowers, Harvey L. Reid, Andre Greenidge, Clive Landis, Marvin Reid

The Flavonoid Pathway in Tomato Seedlings: Transcript Abundance and the Modeling of Metabolite Dynamics

Marian Groenenboom, Victoria Gomez-Roldan, Hans Stigter, Laura Astola, Raymond van Daelen, Jules Beekwilder, Arnaud Bovy, Robert Hall, Jaap Molenaar

Boolean Network Model for Cancer Pathways: Predicting Carcinogenesis and Targeted Therapy Outcomes

Herman F. Fumi？, Marcelo L. Martins

Behaviour of Non-Donor Specific Antibodies during Rapid Re-Synthesis of Donor Specific HLA Antibodies after Antibody Incompatible Renal Transplantation

Nithya S. Krishnan, Daniel Zehnder, Sunil Daga, Dave Lowe, F. T. Lam, Habib Kashi, Lam Chin Tan, Christopher Imray, Rizwan Hamer, David Briggs, Neil Raymond, Robert M. Higgins

MiR-376c Down-Regulation Accelerates EGF-Dependent Migration by Targeting GRB2 in the HuCCT1 Human Intrahepatic Cholangiocarcinoma Cell Line

Jun Iwaki, Kunio Kikuchi, Yoshiaki Mizuguchi, Yutaka Kawahigashi, Hiroshi Yoshida, Eiji Uchida, Toshihiro Takizawa

Land Suitability Assessment on a Watershed of Loess Plateau Using the Analytic Hierarchy Process

Xiaobo Yi, Li Wang

Black Tea High-Molecular-Weight Polyphenol Stimulates Exercise Training-Induced Improvement of Endurance Capacity in Mouse via the Link between AMPK and GLUT4

Tomoaki Eguchi, Chiaki Kumagai, Takashi Fujihara, Thoru Takemasa, Tetsuo Ozawa, Osamu Numata

Childhood Chronic Physical Aggression Associates with Adult Cytokine Levels in Plasma

Nadine Proven？al, Matthew J. Suderman, Frank Vitaro, Moshe Szyf, Richard E. Tremblay

Physical Activity in Deprived Communities in London: Examining Individual and Neighbourhood-Level Factors

Paul Watts, Gemma Phillips, Mark Petticrew, Richard Hayes, Christian Bottomley, Ge Yu, Elena Schmidt, Patrick Tobi, Derek Moore, Caroline Frostick, Karen Lock, Adrian Renton

Modeling the Minimal Newborn's Intersubjective Mind: The Visuotopic-Somatotopic Alignment Hypothesis in the Superior Colliculus

Alexandre Pitti, Yasuo Kuniyoshi, Mathias Quoy, Philippe Gaussier

Development of a Nuclear Morphometric Signature for Prostate Cancer Risk in Negative Biopsies

Peter H. Gann, Ryan Deaton, Anup Amatya, Mahesh Mohnani, Erika Enk Rueter, Yirong Yang, Viju Ananthanarayanan

An Impact Study of the Design of Exergaming Parameters on Body Intensity from Objective and Gameplay-Based Player Experience Perspectives, Based on Balance Training Exergame

Tien-Lung Sun, Chia-Hsuan Lee

Outcomes and Impact of HIV Prevention, ART and TB Programs in Swaziland – Early Evidence from Public Health Triangulation

Cari van Schalkwyk, Sibongile Mndzebele, Thabo Hlophe, Jesus Maria Garcia Calleja, Eline L. Korenromp, Rand Stoneburner, Cyril Pervilhac

Assessing Gibberellins Oxidase Activity by Anion Exchange/Hydrophobic Polymer Monolithic Capillary Liquid Chromatography-Mass Spectrometry

Ming-Luan Chen, Xin Su, Wei Xiong, Jiu-Feng Liu, Yan Wu, Yu-Qi Feng, Bi-Feng Yuan

Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice

Heidi E. Godoy, A. Nazmul H. Khan, R. Robert Vethanayagam, Melissa J. Grimm, Kelly L. Singel, Nonna Kolomeyevskaya, Kevin J. Sexton, Anupama Parameswaran, Scott I. Abrams, Kunle Odunsi, Brahm H. Segal

Bayesian Detection of Causal Rare Variants under Posterior Consistency

Faming Liang, Momiao Xiong

Track-A-Worm, An Open-Source System for Quantitative Assessment of C. elegans Locomotory and Bending Behavior

Sijie Jason Wang, Zhao-Wen Wang

Genetic Variation in the NOC Gene Is Associated with Body Mass Index in Chinese Subjects

Yi-Cheng Chang, Yen-Feng Chiu, Pi-Hua Liu, Siow Wei Hee, Tien-Jyun Chang, Yi-Der Jiang, Wei-Jei Lee, Po-Chu Lee, Hui-Yi Kao, Juey-Jen Hwang, Lee-Ming Chuang

Low Immunogenicity of Neural Progenitor Cells Differentiated from Induced Pluripotent Stem Cells Derived from Less Immunogenic Somatic Cells

Pengfei Liu, Shubin Chen, Xiang Li, Li Qin, Ke Huang, Lihui Wang, Wenhao Huang, Shengbiao Li, Bei Jia, Mei Zhong, Guangjin Pan, Jinglei Cai, Duanqing Pei

Majority Rules with Random Tie-Breaking in Boolean Gene Regulatory Networks

Claudine Chaouiya, Ouerdia Ourrad, Ricardo Lima

Transcriptomic Analysis of Insulin-Sensitive Tissues from Anti-Diabetic Drug Treated ZDF Rats, a T2DM Animal Model

Yo Na Kim, Sangok Kim, Il-Yong Kim, Jae Hoon Shin, Sooyoung Cho, Sun Shin Yi, Wan Kyu Kim, Kyung-Sub Kim, Sanghyuk Lee, Je Kyung Seong

Validation of Next Generation Sequencing Technologies in Comparison to Current Diagnostic Gold Standards for BRAF, EGFR and KRAS Mutational Analysis

Clare M. McCourt, Darragh G. McArt, Ken Mills, Mark A. Catherwood, Perry Maxwell, David J. Waugh, Peter Hamilton, Joe M. O'Sullivan, Manuel Salto-Tellez

Spatial Relationships between GABAergic and Glutamatergic Synapses on the Dendrites of Distinct Types of Mouse Retinal Ganglion Cells across Development

Adam Bleckert, Edward D. Parker, YunHee Kang, Raika Pancaroglu, Florentina Soto, Renate Lewis, Ann Marie Craig, Rachel O. L. Wong

The Effect of Criticism on Functional Brain Connectivity and Associations with Neuroticism

Michelle Nadine Servaas, Harri？tte Riese, Remco Jan Renken, Jan-Bernard Cornelis Marsman, Johan Lambregs, Johan Ormel, André Aleman

Dimerization of the Glucan Phosphatase Laforin Requires the Participation of Cysteine 329

Pablo Sánchez-Martín, Madushi Raththagala, Travis M. Bridges, Satrio Husodo, Matthew S. Gentry, Pascual Sanz, Carlos Romá-Mateo

Temporal but Not Spatial Variability during Gait Is Reduced after Selective Dorsal Rhizotomy in Children with Cerebral Palsy

Mustafa Sinan Bakir, Franziska Gruschke, William R. Taylor, Ernst Johannes Haberl, Ilya Sharankou, Carsten Perka, Julia F. Funk

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