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PLOS ONE

ISSN Print: 1932-6203

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主页: http://www.plosone.org/

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How Many Seals Were There? The Global Shelf Loss during the Last Glacial Maximum and Its Effect on the Size and Distribution of Grey Seal Populations

Lars Boehme, Dave Thompson, Mike Fedak, Don Bowen, Mike O. Hammill, Garry B. Stenson

All-Trans-Retinoic Acid Modulates ICAM-1 N-Glycan Composition by Influencing GnT-III Levels and Inhibits Cell Adhesion and Trans-Endothelial Migration

Changguo Chen, Dekun Diao, Liang Guo, Ming Shi, Jie Gao, Meiru Hu, Ming Yu, Lu Qian, Ning Guo

Multi-Analyte Network Markers for Tumor Prognosis

Jongkwang Kim, Long Gao, Kai Tan

Can a Threshold Value Be Used to Classify Chondrichthyan Reproductive Modes: Systematic Review and Validation Using an Oviparous Species

Holly A. Frazer, Megan Ellis, Charlie Huveneers

Efficacy of Virtual Reality Exposure Therapy in the Treatment of PTSD: A Systematic Review

Raquel Gon？alves, Ana Lúcia Pedrozo, Evandro Silva Freire Coutinho, Ivan Figueira, Paula Ventura

Gender and Ethnicity Differences in HIV-related Stigma Experienced by People Living with HIV in Ontario, Canada

Mona R. Loutfy, Carmen H. Logie, Yimeng Zhang, Sandra L. Blitz, Shari L. Margolese, Wangari E. Tharao, Sean B. Rourke, Sergio Rueda, Janet M. Raboud

Physically-Induced Cytoskeleton Remodeling of Cells in Three-Dimensional Culture

Sheng-Lin Lee, Ali Nekouzadeh, Boyd Butler, Kenneth M. Pryse, William B. McConnaughey, Adam C. Nathan, Wesley R. Legant, Pascal M. Schaefer, Robert B. Pless, Elliot L. Elson, Guy M. Genin

Depressive Symptoms and Cardiovascular Health by the American Heart Association’s Definition in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study

Ian M. Kronish, April P. Carson, Karina W. Davidson, Paul Muntner, Monika M. Safford

Tissue Factor Pathway Inhibitor 2 Is Found in Skin and Its C-Terminal Region Encodes for Antibacterial Activity

Praveen Papareddy, Martina Kalle, Ole E. S？rensen, Katarina Lundqvist, Matthias M？rgelin, Martin Malmsten, Artur Schmidtchen

The Right Time to Happen: Play Developmental Divergence in the Two Pan Species

Elisabetta Palagi, Giada Cordoni

Telomere Length and Long-Term Endurance Exercise: Does Exercise Training Affect Biological Age? A Pilot Study

Ida Beate ？. ？sthus, Antonella Sgura, Francesco Berardinelli, Ingvild Vatten Alsnes, Eivind Br？nstad, Tommy Rehn, Per Kristian St？bakk, H？vard Hatle, Ulrik Wisl？ff, Javaid Nauman

Identification of Optogenetically Activated Striatal Medium Spiny Neurons by Npas4 Expression

Asim K. Bepari, Hiromi Sano, Nobuaki Tamamaki, Atsushi Nambu, Kenji F. Tanaka, Hirohide Takebayashi

Production of Functional Soluble Dectin-1 Glycoprotein Using an IRES-Linked Destabilized-Dihydrofolate Reductase Expression Vector

Say Kong Ng, Tessa Rui Min Tan, Yang Wang, Daniel Ng, Lin-Tang Goh, Muriel Bardor, Victor Vai Tak Wong, Kong Peng Lam

Magnetic Resonance Imaging Determined Visceral Fat Reduction Associates with Enhanced IL-10 Plasma Levels in Calorie Restricted Obese Subjects

Gloria Formoso, Merilda Taraborrelli, Maria T. Guagnano, Monica D’Adamo, Natalia Di Pietro, Armando Tartaro, Agostino Consoli

Conserved Acidic Amino Acid Residues in a Second RNA Recognition Motif Regulate Assembly and Function of TDP-43

Akemi Shodai, Akemi Ido, Noriko Fujiwara, Takashi Ayaki, Toshifumi Morimura, Miki Oono, Tsukasa Uchida, Ryosuke Takahashi, Hidefumi Ito, Makoto Urushitani

Historical and Contemporary DNA Indicate Fisher Decline and Isolation Occurred Prior to the European Settlement of California

Jody M. Tucker, Michael K. Schwartz, Richard L. Truex, Kristine L. Pilgrim, Fred W. Allendorf

Maternally Administered Sustained-Release Naltrexone in Rats Affects Offspring Neurochemistry and Behaviour in Adulthood

Waleed O. Farid, Andrew J. Lawrence, Elena V. Krstew, Robert J. Tait, Gary K. Hulse, Sarah A. Dunlop

WARP Interacts with Collagen VI-Containing Microfibrils in the Pericellular Matrix of Human Chondrocytes

Uwe Hansen, Justin M. Allen, Rachel White, Cathleen Moscibrocki, Peter Bruckner, John F. Bateman, Jamie Fitzgerald

Impact of CD68/(CD3+CD20) Ratio at the Invasive Front of Primary Tumors on Distant Metastasis Development in Breast Cancer

Noemí Eiró, Iván Pidal, Belen Fernandez-Garcia, Sara Junquera, Maria L. Lamelas, José M. del Casar, Luis O. González, Alfonso López-Mu？iz, Francisco J. Vizoso

HCMV Protein LUNA Is Required for Viral Reactivation from Latently Infected Primary CD14+ Cells

Lisa R. Keyes, Danna Hargett, Melisa Soland, Mariana G. Bego, Cyprian C. Rossetto, Graca Almeida-Porada, Stephen St. Jeor

Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo

Vincent Soubannier, Peter Rippstein, Brett A. Kaufman, Eric A. Shoubridge, Heidi M. McBride

Oscillation of an Anuran Hybrid Zone: Morphological Evidence Spanning 50 Years

Jean-Sébastien Roy, David O’Connor, David M. Green

From Mind to Mouth: Event Related Potentials of Sentence Production in Classic Galactosemia

Inge Timmers, Bernadette M. Jansma, M. Estela Rubio-Gozalbo

Extended and Structurally Supported Insights into Extracellular Hormone Binding, Signal Transduction and Organization of the Thyrotropin Receptor

Gerd Krause, Annika Kreuchwig, Gunnar Kleinau

Targeted Delivery of GDNF through the Blood–Brain Barrier by MRI-Guided Focused Ultrasound

Feng Wang, Yu Shi, Lin Lu, Li Liu, Youli Cai, Hairong Zheng, Xin Liu, Fei Yan, Chao Zou, Chengyu Sun, Jie Shi, Shukun Lu, Yun Chen

Multiple Protein Biomarker Assessment for Recombinant Bovine Somatotropin (rbST) Abuse in Cattle

Susann K. J. Ludwig, Nathalie G. E. Smits, Grishja van der Veer, Maria G. E. G. Bremer, Michel W. F. Nielen

Mechanism of Fcγ Receptor-Mediated Trogocytosis-Based False-Positive Results in Flow Cytometry

Sakiko Masuda, Sari Iwasaki, Utano Tomaru, Juri Sato, Ai Kawakami, Kana Ichijo, Sayuri Sogo, Tomohisa Baba, Kazuaki Katsumata, Masanori Kasahara, Akihiro Ishizu

MRI Characterization of Paranodal Junction Failure and Related Spinal Cord Changes in Mice

Morito Takano, Keigo Hikishima, Kanehiro Fujiyoshi, Shinsuke Shibata, Akimasa Yasuda, Tsunehiko Konomi, Akiko Hayashi, Hiroko Baba, Koichi Honke, Yoshiaki Toyama, Hideyuki Okano, Masaya Nakamura

Artificial Cervical Vertebra and Intervertebral Complex Replacement through the Anterior Approach in Animal Model: A Biomechanical and In Vivo Evaluation of a Successful Goat Model

Jie Qin, Xijing He, Dong Wang, Peng Qi, Lei Guo, Sihua Huang, Xuan Cai, Haopeng Li, Rui Wang

Multiploid CD61+ Cells Are the Pre-Dominant Cell Lineage Infected during Acute Dengue Virus Infection in Bone Marrow

Kristina B. Clark, Sansanee Noisakran, Nattawat Onlamoon, Hui-Mien Hsiao, John Roback, Francois Villinger, Aftab A. Ansari, Guey Chuen Perng

Differential Expression of Alpha 4 Integrins on Effector Memory T Helper Cells during Bordetella Infections. Delayed Responses in Bordetella pertussis

Tuan M. Nguyen, Dipti Ravindra, Brian Kwong, Sana Waheed, Ryan Ferguson, Nicole Tarlton, Victoria Wu, Christopher S. Sequeira, Martina Bremer, Tzvia Abramson

Incidence and Risk Factors for Placenta Accreta/Increta/Percreta in the UK: A National Case-Control Study

Kathryn E. Fitzpatrick, Susan Sellers, Patsy Spark, Jennifer J. Kurinczuk, Peter Brocklehurst, Marian Knight

Glitter-Like Iridescence within the Bacteroidetes Especially Cellulophaga spp.: Optical Properties and Correlation with Gliding Motility

Betty Kientz, Adrien Ducret, Stephen Luke, Peter Vukusic, Tam Mignot, Eric Rosenfeld

PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites

Jürgen Glas, Julia Seiderer, Darina Czamara, Giulia Pasciuto, Julia Diegelmann, Martin Wetzke, Torsten Olszak, Christiane Wolf, Bertram Müller-Myhsok, Tobias Balschun, Jean-Paul Achkar, M. Ilyas Kamboh, Andre Franke, Richard H. Duerr, Stephan Brand

A Model-Based Clustering Method for Genomic Structural Variant Prediction and Genotyping Using Paired-End Sequencing Data

Matthew Hayes, Yoon Soo Pyon, Jing Li

Positioning of Chromosomes in Human Spermatozoa Is Determined by Ordered Centromere Arrangement

Olga S. Mudrak, Igor B. Nazarov, Estella L. Jones, Andrei O. Zalensky

Ofd1 Controls Dorso-Ventral Patterning and Axoneme Elongation during Embryonic Brain Development

Anna D'Angelo, Amalia De Angelis, Bice Avallone, Immacolata Piscopo, Roberta Tammaro, Michèle Studer, Brunella Franco

RET/GFRα Signals Are Dispensable for Thymic T Cell Development In Vivo

Afonso Rocha Martins Almeida, Sílvia Arroz-Madeira, Diogo Fonseca-Pereira, Hélder Ribeiro, Reena Lasrado, Vassilis Pachnis, Henrique Veiga-Fernandes

Synergistic Inhibition of Wnt Pathway by HIF-1α and Osteoblast-Specific Transcription Factor Osterix (Osx) in Osteoblasts

Dafu Chen, Yang Li, Zhiyu Zhou, Yonggang Xing, Yu Zhong, Xuenong Zou, Wei Tian, Chi Zhang

Acute Hypersensitivity of Pluripotent Testicular Cancer-Derived Embryonal Carcinoma to Low-Dose 5-Aza Deoxycytidine Is Associated with Global DNA Damage-Associated p53 Activation, Anti-Pluripotency and DNA Demethylation

Bijesh K. Biswal, Maroun J. Beyrouthy, Mary P. Hever-Jardine, David Armstrong, Craig R. Tomlinson, Brock C. Christensen, Carmen J. Marsit, Michael J. Spinella

Express Your LOV: An Engineered Flavoprotein as a Reporter for Protein Expression and Purification

Jayde A. Gawthorne, L. Evan Reddick, Snezhana N. Akpunarlieva, Katherine S. H. Beckham, John M. Christie, Neal M. Alto, Mads Gabrielsen, Andrew J. Roe

A Variant In the Abo Gene Explains the Variation in Soluble E-Selectin Levels—Results from Dense Genotyping in Two Independent Populations

Mahir Karakas, Jens Baumert, Marcus E. Kleber, Barbara Thorand, Dhayana Dallmeier, Günther Silbernagel, Tanja B. Grammer, Wolfgang Rottbauer, Christa Meisinger, Thomas Illig, Winfried M？rz, Wolfgang Koenig

A Ferritin from Dendrorhynchus zhejiangensis with Heavy Metals Detoxification Activity

Chenghua Li, Zhen Li, Ye Li, Jun Zhou, Chundan Zhang, Xiurong Su, Taiwu Li

Comparisons of Prediction Models of Quality of Life after Laparoscopic Cholecystectomy: A Longitudinal Prospective Study

Hon-Yi Shi, Hao-Hsien Lee, Jinn-Tsong Tsai, Wen-Hsien Ho, Chieh-Fan Chen, King-Teh Lee, Chong-Chi Chiu

Enhanced Biofilm Formation by Escherichia coli LPS Mutants Defective in Hep Biosynthesis

Ryoma Nakao, Madeleine Ramstedt, Sun Nyunt Wai, Bernt Eric Uhlin

Interleukin-15-Induced CD56+ Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential

Sébastien Anguille, Eva Lion, Jurjen Tel, I. Jolanda M de Vries, Karen Couderé, Phillip D. Fromm, Viggo F. Van Tendeloo, Evelien L. Smits, Zwi N. Berneman

Cell Surface Concentrations and Concentration Ranges for Testing In Vitro Autocrine Loops and Small Molecules

Nikhil Mittal

Molecular and Cellular Response Profiles Induced by the TLR4 Agonist-Based Adjuvant Glucopyranosyl Lipid A

Stacie L. Lambert, Chin-Fen Yang, Zheng Liu, Rosemary Sweetwood, Jackie Zhao, Lily Cheng, Hong Jin, Jennifer Woo

Cell-Free (RNA) and Cell-Associated (DNA) HIV-1 and Postnatal Transmission through Breastfeeding

James Ndirangu, Johannes Viljoen, Ruth M. Bland, Siva Danaviah, Claire Thorne, Philippe Van de Perre, Marie-Louise Newell

What Maintains the Central North Pacific Genetic Discontinuity in Pacific Herring?

Ming Liu, Longshan Lin, Tianxiang Gao, Takashi Yanagimoto, Yasunori Sakurai, W. Stewart Grant

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