Breast cancer is the most common and deadliest cancer in women. The association of breast cancer and pregnancy is relatively rare and has a poor prognosis due to often late diagnosis and a high potential for lymphatic dissemination. It poses many diagnostic, therapeutic, prognostic and psychological problems. We report a case of ductal carcinoma of the breast associated with pregnancy in a 27-year-old patient. The diagnosis was late as well as the care which began 4 weeks after delivery. Obstetr...

Gynecology & Obstetrics  Oncology  Women’s Health 

Background: Salivary duct carcinoma (SDC) is one of the most aggressive malignant salivary gland tumors resembling high-grade mammary ductal carcinoma, with frequent local recurrence and regional lymph node and distant metastasis. SDC is often the absence of estrogen receptor and progesterone receptor, and Her2/neu overexpression. Treatment with molecular targeted therapy correlated well with long-term survival and therapeutic response in SDC patients. Purpose: We presented the clinicopathologic...

Oncology 

Neuroendocrine carcinoma (NEC) is a malignant tumor with a poor prognosis and can grow at many different sites in the body, but the colon is a very rare site. Clinical Case: We report a case of a 62-year-old man operated on for a tumor of the cecum, which was diagnosed as a high-grade neuroendocrine carcinoma. An immunohistochemical study showed positive marking with synaptophysin. No cancer metastasis was found. Postoperative chemotherapy was applied but the patient died after ...

Oncology  Surgery & Surgical Specialties 

Pott’s puffy tumour is a subperiosteal abscess of the frontal bone with osteomyelitis which has become rare because of the widespread use of antibiotics [1]. It is usually seen as a complication of frontal sinusitis [2]. Here we report a case of Pott’s puffy tumour (PPT) in a 71-year-old man who visited the accident & emergency department with painful swelling of the forehead but with no reported antecedent history of any symptoms of rhinitis or sinusitis. The application of a high index of clin...

Oncology 

Choledochal cyst is a rare pathological condition, which represents 1% of benign diseases of the biliary tract. It is seen with significant frequency in childhood, with a higher prevalence in females. Diagnosis is primarily based on clinical suspicion. Its symptoms are variable and its treatment, depending on the type, is surgical. Case Report: A 5-year-old female childhood, weighing 20 kg presented with a two weeks history of upper abdominal pain, jaundice and low-grade fever for 8 days, accomp...

Oncology  Surgery & Surgical Specialties 

Lipomas are ubiquitous soft tissue swellings that can be found in any part of the body. They are the commonest non-malignant tumours of the fatty tissue with varying sizes. When they are more than 10 cm in size along any dimension or weigh more than 1000 g, they are described as giant lipomas. I present a case of giant lipoma of the scalp, managed in Jonex Hospital, Aba, Nigeria. After clinical and relevant radiological investigations to characterize and ascertain the extent of the scalp lesion,...

Oncology 

Objective: To investigate the clinicopathological features and surgical treatment of differentiated thyroid isthmus carcinoma. Methods: The clinical data of 76 patients with differentiated thyroid isthmus cancer diagnosed and operated in our hospital from January 2015 to January 2019 were retrospectively analyzed. Results: 16 cases of single focus, 60 cases with unilateral or bilateral multiple lesions, 76 patients. Bilateral thyroidectomy and bilateral CLN dissection were performed in 57 cases,...

Oncology 

The hallmarks of cancer are determined by cancer-associated gene expression pattern that is determined by cancer-associated chromatin configuration (CACC). Using non-carcinogenic genotoxic drugs (NCGDs) to alter CACC could change cancer-associated gene expression pattern, which in turn, might cause disappearance of some or whole hallmarks of cancer and as a result, cancer cells could be killed by either apoptosis or immune destruction. Therefore, cancer could be prevented and treated by administ...

Molecular Biology  Cell Biology  Oncology 

Intimal sarcoma is a rare type of mesenchymal tumor that arises from the intima of large and small vessels. Most commonly it arises from the pulmonary artey or the thoracic aorta. We report a case diagnosed with right pulmonary artery intimal sarcoma after CT guided biopsy. The patient underwent surgical excision of the tumor successfully without residual and no post-operative complications, then received adjuvant chemotherapy. Patient was disease free till her last follow up in 12/2020. Conclus...

Oncology 

Background: Breast cancer is the most common cancer in women worldwide. Breast cancer represents about 13% of all new cancer cases in both male and female yearly and represents about 22.8% of cancer cases among female patients in Yemen. Objective: To study the early complications following modified radical mastectomy among patients diagnosed with breast cancer and evaluate some risk factors and associated comorbidity. Methods: The present prospective and observational study was conducted in Al-G...

Oncology  Surgery & Surgical Specialties