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Jun 13, 2025Open Access
Male breast cancer (MBC) is a rare but impactful condition, constituting approximately 1% of all breast cancer cases. Due to its rarity, MBC often goes undiagnosed until later stages, and affected individuals face significant psychological and social challenges compounded by public misconceptions and a lack of tailored support. This study explores the emotional, psychological, and social impacts of MBC through a survey of 47 diagnosed male patients using validated assessment tools (HADS, IES-R, ...
Apr 08, 2025Open Access
Objective: The aim of the present study is to assess the role of the level of change in gene expression of the HOTAIR molecule in breast cancer patients. Methods: An assay was conducted for the level of gene expression of the HOTAIR molecule in the plasma of 30 patients and 10 healthy controls, by performing the reverse transcription reaction RT-qPCR, gene expression was evaluated using the Livak equation, tumor characteristics (grade, HER2 receptors, hormonal (...
Feb 18, 2025Open Access
Background: Glioblastoma is the most prevalent and aggressive primary malignant brain tumor, known for its rapid growth and local invasion. While it predominantly remains within the central nervous system, extracranial metastasis is extremely rare, involving the liver, lymph nodes, thorax, spleen, and bones. Thoracic involvement is often associated with the worst prognosis. Aim: This paper presents a unique case of lung metastasis from glioblastoma, highlighting...
Feb 17, 2025Open Access
Background: Renal metastases from non-small cell lung cancer (NSCLC) are rare, treatment guidelines for renal metastases from NSCLC are unclear, mostly based on clinical case reports. Data on the effectiveness of osimertinib in the group of patients with renal metastatic NSCLC who have epidermal growth factor receptor (EGFR) mutations del19 or L858R is still incomplete. Purpose: In this study, we report a case of the bilateral renal metastatic NSCLC who was treated by the first...
Jan 09, 2025Open Access
Background: Cerebellopontine (CP) angle in adults may harbor a number of tumors. The most common tumors in this location include schwannoma, meningioma, and epidermoid tumor followed by metastatic lesions. Cerebellopontine angle (CPA) is an atypical site for adult medulloblastoma (MB) with only 13 cases reported in pure extra-axial location. Cases Présentations: We report a case of 22-year-old male, both presented with headache, vomiting, ataxia Magnetic resonan...
Jan 08, 2025Open Access
Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, hold significant promise for in vivo visualization, due to their ability to access biological tissues and significantly reduce background interference from autofluorescence. Nanoparticles integrated with IR dyes have undergone extensive investigation regarding their pharmacokinetic behavior, including biodistribution patterns and clearance mechanisms. These nanoparticles exhibit a remarkable ability to prefere...
Nov 22, 2024Open Access
Objective: To assess the value of MRI in the diagnosis of brain metastases due to the main primary tumours in patients who have undergone MRI at the CNSS. Methods: This is a retrospective, descriptive study of 3 years and 7 months duration from January 2019 to July 2023 involving 24 cases. We included in our study, all records of patients whose brain MRI was interpreted as being in favour of brain metastases. The examinations were performed using a TOSHIBA (CANO...
Sep 24, 2024Open Access
Sarcomatoid carcinoma is a rare and aggressive tumor that can occur in various organs, including the stomach. We aim to present a case of metastatic gastric sarcomatoid carcinoma and highlight the challenges in its diagnosis and treatment. We report the case of a 72-year-old female patient with metastatic gastric sarcomatoid carcinoma. The patient presented with intractable nausea, vomiting, abdominal pain, and significant weight loss. Imaging studies revealed a large tumor in the antropyloric r...
Sep 19, 2024Open Access
Research background: The FAST FORWARD protocol is a hypo-fractionated treatment regimen for early breast cancer, generally involving fewer sessions with higher doses per fraction compared to traditional regimens. Application of DIBH minimize radiation exposure to the heart and lungs during treatment of left-sided breast cancer. Research objectives: The aim of the present study, was to compare the dosimetric goals properties of the restricted tangential Intensity...
Aug 29, 2024Open Access
This study compares logit and probit regression models to analyze the likelihood of lung cancer occurrence based on patient data and lifestyle factors. The results reveal significant associations between lung cancer and patients’ age, gender, smoking status, yellow finger, anxiety, chronic disease, fatigue, allergy, wheezing, alcohol consumption, coughing, shortness of breath, swallowing difficulty, and chest pain. The result shows that the probit model better predicts lung cancer based on the f...
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