Objective: Vitamin D, a key regulator of phosphocalcic metabolism, plays a central role in bone remodeling—a fundamental process underlying orthodontic tooth movement and post-treatment stability. Its specific influence on orthodontic outcomes, and in particular on relapse prevention, remains insufficiently characterized. This review systematizes the recent evidence on the role of vitamin D in orthodontics, focusing on its biological mechanisms and its potential to enhance treatment...

Dentistry 

Introduction: Pyeloureteral junction syndrome is the most common of the congenital obstructive uropathies. Her annual impact is evaluated at 5 for 100,000 in the general population in Senegal. Its frequency ranged from 1 to 10 across 5000 births. Dynamic renal scintigraphy (DRS) with hyperdiuresis testing has two aims: to define the impact of urinary tract obstruction on renal function and to assess the severity of the obstruction and the flow of the urine. Our objective was to evaluate t...

Nuclear Technology  Nuclear Physics 

This paper argues that heavy reliance on military counterterrorism since 9/11 can weaken trust, disrupt local social order, and push affected communities toward noncooperation or support for armed groups. It uses a qualitative, conceptual discussion supported by case examples, policy documents, and secondary literature. Its main conclusion is that counterterrorism should be judged less by enemy attrition and more by whether it builds legitimacy, community trust, and resilience.

Military Science  Sociology 

Introduction: Acute respiratory infections (ARIs) remain a significant cause of childhood morbidity in resource-limited settings. In the Kamina Health Zone of the Democratic Republic of the Congo, where a large proportion of the population lives in poverty and has limited access to specialized diagnostic services, the early identification of ARIs is a major challenge. Peak expiratory flow (PEF), a simple, rapid, and inexpensive tool, could be a useful complement to clinical assessment. Th...

Global Health 

Antidepressant-associated cycle acceleration (AICA), encompassing antidepressant-related switching, rapid-cycling induction or acceleration, and mixed-state emergence, is an important treatment-safety concern in bipolar disorder (BD). Because these outcomes may be difficult to distinguish from spontaneous illness progression, pre-initiation risk stratification is clinically relevant. This proof-of-concept simulation study evaluates whether a multivariate machine-learning framework can recover pr...

Artificial Intelligence  Psychiatry & Psychology 

Selective serotonin reuptake inhibitor (SSRI)-associated mood destabilisation, encompassing hypomania, mania, and mixed-state induction, is an important pharmacological safety concern in bipolar disorder. Current clinical decision-making relies largely on static baseline risk factors and therefore may not capture the temporal evolution of symptoms, medication exposure, adherence, sleep, and physiological measures across follow-up visits. This methodological proof-of-concept study evaluates wheth...

Artificial Intelligence  Psychiatry & Psychology 

Beans are the main source of protein in most Ugandan households, and they are also a cash crop in most rural households. Despite the importance of beans in Uganda’s economy and rural livelihoods, their productivity has been persistently low, mainly due to declining soil fertility in smallholder farming systems. A farm soil fertility trial was established in the semi-arid and humid sub-agroecological zones of southwestern Uganda with five farmer groups. Each farmer group had one learning si...

Food Science & Technology  Agricultural Science 

In previous articles, we proposed explaining the dark matter (DM) component, without invoking exotic matter, by utilizing the second component of General Relativity (GR) responsible for the Lense-Thirring effect. While the first component is the “$g$” Newtonian field, we designate this second component as the “$k$” gravitic field. In GR, the k...

Classical Physics 

Treatment-resistant bipolar depression (TRD-BD), defined in this simulation as failure to achieve remission after at least two adequate pharmacological trials for the current bipolar depressive episode, including at least one antidepressant trial delivered with mood-stabilising treatment, is managed through a sequence of uncertain decisions: continue, switch antidepressant class, or augment with a mood stabiliser or atypical antipsychotic. Current practice relies on consensus bipolar-disorder gu...

Artificial Intelligence  Psychiatry & Psychology 

Depressive episodes in bipolar disorder are preceded by a prodromal phase in which subtle physiological and behavioural changes reduced daytime activity, fragmented and lengthened sleep, blunted circadian rhythm, diminished heart rate variability, and social withdrawal emerge before the patient or clinician recognises a clinical episode. Digital phenotyping, the continuous passive collection of behavioural and physiological data from wearable sensors and smartphones, offers an unprecedented wind...

Artificial Intelligence  Psychiatry & Psychology