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May 28, 2026Open Access
Schizophrenia has been increasingly conceptualized as a neurodevelopmental disorder with potential neurodegenerative components, yet evidence for progressive brain changes remains controversial. We investigated longitudinal trajectories of structural, functional, and cognitive biomarkers to characterize neurodegenerative patterns in schizophrenia using machine learning approaches. We analysed longitudinal neuroimaging and cognitive data from 150 participants (75 schizophrenia patients, 75 health...
May 28, 2026Open Access
This article pertains to EXOS-C’s LEO observations during 1984-1986 of quasi-trapped protons (0.64 - 35 MeV) and electrons (0.19 - 3.2 MeV) with the main focus on the former. The temporal variation of proton population near the geomagnetic equator reveals that the peak value of the equatorially mirroring component may increase by a factor of 50 or more between a solar maximum and a minimum condition, and that the peak flux profile of protons in the equatorial, low latitude, midlatitude, and auro...
May 28, 2026Open Access
Psychiatric decision support systems hold promise for improving clinical outcomes, yet their development is hindered by data privacy regulations and institutional silos that prevent aggregation of sensitive patient information across healthcare facilities. This proof-of-concept simulation demonstrates that privacy-preserving federated learning can match centralized training performance under synthetic non-IID conditions; real-world validation on operational electronic health record data is requi...
May 28, 2026Open Access
This study aimed to explore issues and practices related to quality training delivery in North Shewa Zone TVET colleges. A mixed-method research design was utilized. A questionnaire, semi-structured interviews, and document analysis were incorporated. Out of 296 questionnaires distributed, 285 valid responses were obtained (response rate = 96.3%), 171 trainees, 66 trainers, 36 staff, and 12 management personnel. Data were analyzed by using descriptive statistics and thematic analysis. The study ...
May 28, 2026Open Access
Digital transformation is increasingly influencing the Technical and Vocational Education and Training systems worldwide. National initiatives such as Digital Ethiopia 2030 and sectoral reforms in Ethiopia, shown by the basis of integration, have prioritized technology in education. Nevertheless, the evidence pointing to elements of successful digital technology integration in competency-based training and their association with student learning outcomes is limited across Ethiopian TVET institut...
May 28, 2026Open Access
Treatment selection for bipolar depression remains largely trial-and-error, with substantial non-response to first-line strategies and clinically meaningful risk of mood destabilization. We developed a deep reinforcement learning (RL) framework to optimize treatment selection while explicitly penalizing destabilization events. We implemented RL-CADENCE, a simulated multi-centre experimental framework designed to emulate a parallel-group randomized trial across 12 virtual psychiatric centres. Usi...
May 28, 2026Open Access
Psychiatric comorbidity in liaison psychiatry is not random noise, it follows structured, clinically meaningful patterns that standard episodic assessment cannot detect. Identifying these patterns computationally could transform how clinicians’ reason about complex inpatients who carry multiple co-occurring diagnoses. We introduce PsychoGraph-Net, an end-to-end graph-attentive deep learning framework that ingests electronic health record (EHR) data, constructs a weighted psychiatric comorbidity ...
May 28, 2026Open Access
Kenyan youth make up a large share of the population, yet many especially in the informal settlement have no consistent adult guidance through their teenage years. This study explored the relationship between mentors and Positive Youth Development (PYD) for secondary-school adolescents in Kibra-Nairobi County. The focus was on mentor relationships, longevity of support, role models, and positive affirmation. The study employed a cross-sectional convergent parallel design, with an overall sample ...
May 28, 2026Open Access
Zinc is an essential element for living organisms which plays an important role in the metabolism of proteins and nucleic acids, participating in the activity of approximately 100 enzymes and collaborating in the proper functioning of the immune system. Deficiency of Zn(II) is associated with growth retardation, impaired immune response, premature birth, weight loss and anorexia. On the other hand, adaptogens are a unique group of herbal ingredients used to improve the health of the adrenal syst...
May 28, 2026Open Access
This paper studies tensor products of bounded linear operators on Hilbert spaces. It establishes bilinearity of the tensor product mapping and shows that key operator properties, including rank-one, finite-rank, compactness, and injectivity, are preserved under tensorization. Spectral behavior is analyzed at the level of eigenvalues, where multiplicativity is obtained. In addition, a structural decomposition for tensor products involving bounded and diagonal operators is derived. The paper also ...
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