Sarcomatoid carcinoma is a rare and aggressive tumor that can occur in various organs, including the stomach. We aim to present a case of metastatic gastric sarcomatoid carcinoma and highlight the challenges in its diagnosis and treatment. We report the case of a 72-year-old female patient with metastatic gastric sarcomatoid carcinoma. The patient presented with intractable nausea, vomiting, abdominal pain, and significant weight loss. Imaging studies revealed a large tumor in the antropyloric region with metastases. Immunohistochemical analysis confirmed the diagnosis of sarcomatoid carcinoma. Despite hospitalization and supportive care, the patient’s condition deteriorated rapidly, leading to her death two weeks after admission. Sarcomatoid carcinoma of the stomach is a rare and highly aggressive malignancy with a poor prognosis. Early detection and novel therapeutic strategies are crucial for improving patient outcomes.
Cite this paper
Soukaina, B. , Chaimae, A. , Salma, N. , Meryem, B. , Hind, M. , Saber, B. , Ibrahim, E. G. and Hassan, E. (2024). Sarcomatoid Carcinoma of the Stomach: A Case Report. Open Access Library Journal, 11, e1992. doi: http://dx.doi.org/10.4236/oalib.1111992.
Zhou, D., Gao, B., Zhang, W., Qian, X., Ying, L. and Wang, W. (2019) Sarcoma-toid Carcinoma of the Pancreas: A Case Report. World Journal of Clinical Cases, 7, 236-241. https://doi.org/10.12998/wjcc.v7.i2.236
Liu, Y., Liang, P., Feng, K., Chen, K., Yue, S., Ji, J., et al. (2020) Computed Tomography Features and Clinicopathological Characteristics of Gastric Sarcomatoid Carcinoma. Fron-tiers in Oncology, 10, Article No. 1611. https://doi.org/10.3389/fonc.2020.01611
Cirocchi, R., Trastulli, S., De-siderio, J., Grassi, V., Barillaro, I., Santoro, A., et al. (2012) Gastric Carcinosar-coma: A Case Report and Review of the Literature. Oncology Letters, 4, 53-57. https://doi.org/10.3892/ol.2012.699
Yoshida, H. (2012) Rapidly De-forming Gastric Carcinosarcoma with Osteoblastic Component: An Autopsy Case Report. World Journal of Gastroenterology, 18, Article No. 4064. https://doi.org/10.3748/wjg.v18.i30.4064
Huang, S., Shen, S. and Li, X. (2013) Pulmonary Sarcomatoid Carcinoma: A Clinicopathologic Study and Prognostic Analysis of 51 Cases. World Journal of Surgical Oncology, 11, Article No. 252. https://doi.org/10.1186/1477-7819-11-252
Lee, J.K., Ghosh, P., McWhorter, V., Payne, M., Olson, R., Krinsky, M.L., et al. (2008) Evidence for Colorectal Sarcomatoid Carcinoma Arising from Tubulovillous Adenoma. World Journal of Gastroenterology, 14, Article No. 4389. https://doi.org/10.3748/wjg.14.4389
Kang, K.A., Yoon, J. and Kang, G. (2013) Sarcomatoid Carcinoma of the Small Intestine: A Case Report and Re-view of the Literature. Journal of the Korean Society of Radiology, 69, Article No. 295. https://doi.org/10.3348/jksr.2013.69.4.295
Izumi, H., Yazawa, N., Furukawa, D., Masuoka, Y., Yamada, M., Mashiko, T., et al. (2016) Carcino-sarcoma of the Ampulla of Vater: A Case Report and Literature Review. Surgical Case Reports, 2, Article No. 102. https://doi.org/10.1186/s40792-016-0233-7
Yam, J.L., Rai, M.P., Ne-makayala, D.R. and Atti, V. (2018) Sarcomatoid Carcinoma of the Duodenum. BMJ Case Reports, 2018, bcr2017223991. https://doi.org/10.1136/bcr-2017-223991
Kwok, C. (2016) Sarcoma-toid Carcinoma of the Jejunum with Gastric Metastases: A Case Report and Re-view of the Literature. International Journal of Surgery Case Reports, 28, 161-164. https://doi.org/10.1016/j.ijscr.2016.09.046
Randjelovic, T. (2007) Carcinosarcoma of the Stomach: A Case Report and Review of the Liter-ature. World Journal of Gastroenterology, 13, Article No. 5533. https://doi.org/10.3748/wjg.v13.i41.5533
Zhang, B., Cheng, B., Wang, L., Zhao, K., Zhuo, G. and Ding, J. (2016) Primary Sarco-matoid Carcinoma of the Jejunum with Massive Intra-Abdominal Hemorrhage: A Case Report and Review of the Literature. Molecular and Clinical Oncology, 4, 811-816. https://doi.org/10.3892/mco.2016.809
