OALib Journal
  OALib Journal is an all-in-one open access journal (ISSN Print: 2333-9705, ISSN Online: 2333-9721). It accepts a manuscript for the peer-review processing, typesetting, publication and then allocated to one of the 322 subject areas. The article processing charge for publishing in OALib journal is Only $99. For more details, please contact service@oalib.com. Submit now
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May 07, 2021Open    AccessArticle

A Novel Strategy for Preventing and Treating Cancer: Alteration of Cancer-Associated Chromatin Configuration

Gao-De Li
The hallmarks of cancer are determined by cancer-associated gene expression pattern that is determined by cancer-associated chromatin configuration (CACC). Using non-carcinogenic genotoxic drugs (NCGDs) to alter CACC could change cancer-associated gene expression pattern, which in turn, might cause disappearance of some or whole hallmarks of cancer and as a result, cancer cells could be killed by either apoptosis or immune destruction. Therefore, cancer could be prevented and treated by administ...
Open Access Library J. Vol.8, 2021

Apr 16, 2021Open    AccessArticle

Intimal Sarcoma of the Pulmonary Artery, Case Report

Emad M. Barsoum, Ashraf M. Habib, Nouran M. Roby
Intimal sarcoma is a rare type of mesenchymal tumor that arises from the intima of large and small vessels. Most commonly it arises from the pulmonary artey or the thoracic aorta. We report a case diagnosed with right pulmonary artery intimal sarcoma after CT guided biopsy. The patient underwent surgical excision of the tumor successfully without residual and no post-operative complications, then received adjuvant chemotherapy. Patient was disease free till her last follow up in 12/2020. Conclus...
Open Access Library J. Vol.8, 2021

Dec 31, 2020Open    AccessArticle

Early Complications Following Modified Radical Mastectomy—Among Breast Cancer Patients Admitted to AL Gomhory Teaching Hospital, Sana’a, Yemen between Jan. 2019-Jan. 2020

Yasser Abdurabbo Obadiel, Mohammed Noaman Al-Ba’adani, Qannaf Hayel Haidar
Background: Breast cancer is the most common cancer in women worldwide. Breast cancer represents about 13% of all new cancer cases in both male and female yearly and represents about 22.8% of cancer cases among female patients in Yemen. Objective: To study the early complications following modified radical mastectomy among patients diagnosed with breast cancer and evaluate some risk factors and associated comorbidity. Methods: The present prospective and observational study was conducted in Al-G...
Open Access Library J. Vol.7, 2020

Nov 20, 2020Open    AccessArticle

Neuroendocrine Carcinoma of the Cervix with Sister Mary Joseph's Nodule: About a Case and Literature Review

Khadija Darif, Karima Oualla, Reda El Hazzaz, Othmane Zouiten, Oumaima Siyouri, Nisrine Acharfi, Raihana Boujarnija, Lamiae Amaadour, Zineb Benbrahim, Samia Arifi, Nawfel Mellas
Neuroendocrine tumors are a rare and aggressive histological variant of the cervix, and they have several differences compared to other types of cervical cancer, in prognosis, diagnosis and treatment. In this paper we report the case of a 39-year-old patient that was taken care of in the medical oncology department at the Hassan II University Hospital Center, for an advanced neuroendocrine carcinoma of the cervix with a Sister Mary Joseph’s nodule. The aim of this work is to highlight this rare ...
Open Access Library J. Vol.7, 2020

Oct 23, 2020Open    AccessArticle

Breast Cancer: A Review of Mammography and Clinical Breast Examination for Early Detection of Cancer

Gadafi Iddrisu Balali, Denis Dekugmen Yar, Vera Gobe Afua Dela, Emmanuel Effah-Yeboah, Philip Asumang, Justice Delali Akoto, Fuseini Abdallah
Worldwide, breast cancer is one of the most common causes of death among women. Undoubtedly, early detection of breast cancer is one of the best ways to manage and treat the disease. According to literature, Mammography and Clinical breast exams are known to be some of the best methods in early detection of breast cancer. Hence information on these two detection methods is very important for planning health policies. This study therefore aimed at reviewing the literature on breast cancer as well...
Open Access Library J. Vol.7, 2020

Sep 27, 2020Open    AccessArticle

HPV-Positive Laryngeal Carcinomas: Epidemiological, Virological and Progressive Features

H. B. Otouana Dzon, G. C. Ngouoni, S. Diembi, G. W. Ondzotto, A. Tsierie-Tsoba, F. A. Itiere Odzili, G. Ondzotto
Objective: The aim of this work was to determine the molecular prevalence of the Human Papilloma Virus (HPV) in carcinomas of the larynx and to identify its circulating genotypes. Patients and Methods: This was a descriptive, retrospective study of 20 years which included all the patients followed in otolaryngology department for laryngeal carcinoma. The virological analysis was done on the laryngeal biopsy pieces included in paraffin using the Gene Xpert technique. This technique uses real-time...
Open Access Library J. Vol.7, 2020

Jul 31, 2020Open    AccessArticle

Biomarker Driven Cancer Therapeutics: Existing Tools and Remaining Gaps

Sasi Shanmugam Senga, Jemma Arakelyan
Advancements in technology such as proteomics, genomics have led to the concept of personalized medicine wherein the integration of biomarkers into clinic directs cancer therapeutics. Traditional staging has a stochastic element which can only predict the outcome without actual consideration of intrapatient heterogeneity. In this review, we will look at the biomarkers that prove to be valuable tools for the personalization of cancer therapeutics among lung and breast cancer patients.
Open Access Library J. Vol.7, 2020

Apr 20, 2020Open    AccessArticle

Orbito-Ethmoidal Rhabdomyosarcoma in an Adult Patient: A Case Report

Nguyen Tien Quang, Pham Tuan Anh, Hoang Thu Hang, Nguyen Phuong Anh
Rhabdomyosarcomas (RMS) is one of the most common sarcomas in children but rare in adults. It can occur in any anatomic location but most often presents in the head and neck region. Herewith, we report a rare case of primary orbito-ethmoidal rhabdomyosarcoma in a 29-year-old female. The patient underwent induction chemotherapy and achieved surprising results.
Open Access Library J. Vol.7, 2020

Jan 08, 2020Open    AccessArticle

Incidence of Chemotherapy-Induced Amenorrhea in Premenopausal Patients with Breast Cancer Following Adjuvant Chemotherapy with Anthracycline and Taxane

Nguyen Tien Quang, Pham Tuan Anh, Le Van Quang, Nguyen Van Hai, Nguyen Duc Huan, Nguyen Cong Tin, Nguyen Thi Thanh Tam, Hoang Thu Hang, Nguyen Thi Thuy, Do Thi Thanh Mai, Tran Hoang Nam, Le Thi Hanga
Breast cancer (BC) is the second incidence and the fifth leading cause to cancer death in the worldwide. In developing countries, the number of BC cases is still increased annually accompanied with the changes of lifestyle and screening programs. Nevertheless, the majority of BC patients are diagnosed as non-curative stage. Thereby, systemic therapy always plays an important role in BC treatment strategies. Among chemotherapy regi
Open Access Library J. Vol.7, 2020

Aug 15, 2019Open    AccessArticle

Knowledge of Risk Factors of Health Professionals towards Colorectal Cancer at the Mohammed VI Center of Casablanca for the Treatment of Cancers

Fatima Ezzahra Imad, Houda Drissi, Nezha Tawfiq, Driss Radallah, Karima Bendahhou
Introduction: Colorectal cancer (CRC) is a major public health problem in Morocco. Knowledge of risk factors is the first step in raising awareness. The objective of this work was to evaluate the knowledge of health professionals working at the Mohammed VI center for the treatment of cancers on risk factors of colorectal cancer. Patients and methods: We conducted a cross-sectional, descriptive, exhaustive study of the hospital per
Open Access Library J. Vol.6, 2019


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