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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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Network Structure and City Size

David Levinson

Spatial Modeling of Vesicle Transport and the Cytoskeleton: The Challenge of Hitting the Right Road

Michael Klann, Heinz Koeppl, Matthias Reuss

The Protein Kinase C Inhibitor Enzastaurin Exhibits Antitumor Activity against Uveal Melanoma

Xinqi Wu, Meijun Zhu, Jonathan A. Fletcher, Anita Giobbie-Hurder, F. Stephen Hodi

An Investigation into the Determining Factors of Zoo Visitor Attendances in UK Zoos

Andrew William Whitworth

Amyloid-Mediated Sequestration of Essential Proteins Contributes to Mutant Huntingtin Toxicity in Yeast

Natalia V. Kochneva-Pervukhova, Alexander I. Alexandrov, Michael D. Ter-Avanesyan

Additive Contributions of Two Manganese-Cored Superoxide Dismutases (MnSODs) to Antioxidation, UV Tolerance and Virulence of Beauveria bassiana

Xue-Qin Xie,Fang Li,Sheng-Hua Ying,Ming-Guang Feng

Electrostatic Contribution of Surface Charge Residues to the Stability of a Thermophilic Protein: Benchmarking Experimental and Predicted pKa Values

Chi-Ho Chan,Cecily C. Wilbanks,George I. Makhatadze,Kam-Bo Wong

Is Primatology an Equal-Opportunity Discipline?

Elsa Addessi,Marta Borgi,Elisabetta Palagi

RhoE Is Regulated by Cyclic AMP and Promotes Fusion of Human BeWo Choriocarcinoma Cells

Gavin P. Collett,Xue Fang Goh,Elizabeth A. Linton,Christopher W. G. Redman,Ian L. Sargent

The Translation Elongation Factor eEF-1Bβ1 Is Involved in Cell Wall Biosynthesis and Plant Development in Arabidopsis thaliana

Zakir Hossain,Lisa Amyot,Brian McGarvey,Margaret Gruber,Jinwook Jung,Abdelali Hannoufa

Stabilisation of the Fc Fragment of Human IgG1 by Engineered Intradomain Disulfide Bonds

Gordana Wozniak-Knopp, Johannes Stadlmann, Florian Rüker

LIPH Expression in Skin and Hair Follicles of Normal Coat and Rex Rabbits

Mathieu Diribarne, Xavier Mata, Julie Rivière, Stéphan Bouet, Anne Vaiman, Jér？me Chapuis, Fabienne Reine, Renaud Fleurot, Gérard Auvinet, Séverine Deretz, Daniel Allain, Laurent Schibler, Edmond-Paul Cribiu, Gérard Guérin

AFM-Detected Apoptotic Changes in Morphology and Biophysical Property Caused by Paclitaxel in Ishikawa and HeLa Cells

Kyung Sook Kim, Chang Hoon Cho, Eun Kuk Park, Min-Hyung Jung, Kyung-Sik Yoon, Hun-Kuk Park

Structural Basis for GTP-Dependent Dimerization of Hydrogenase Maturation Factor HypB

Kwok-Ho Chan, Ting Li, Ching-On Wong, Kam-Bo Wong

Metabolic Regulation of Invadopodia and Invasion by Acetyl-CoA Carboxylase 1 and De novo Lipogenesis

Kristen E. N. Scott, Frances B. Wheeler, Amanda L. Davis, Michael J. Thomas, James M. Ntambi, Darren F. Seals, Steven J. Kridel

The Healing Process of Intracorporeally and In Situ Devitalized Distal Femur by Microwave in a Dog Model and Its Mechanical Properties In Vitro

Zhenwei Ji, Yunlei Ma, Wei Li, Xiaoxiang Li, Guangyi Zhao, Zhe Yun, Jixian Qian, Qingyu Fan

Association of Vitamin B12 Deficiency with Fatigue and Depression after Lacunar Stroke

Marjolein Huijts, Annelien Duits, Julie Staals, Robert J. van Oostenbrugge

HIV-Induced T-Cell Activation/Exhaustion in Rectal Mucosa Is Controlled Only Partially by Antiretroviral Treatment

Cesar Mauricio Rueda,Paula Andrea Velilla,Claire A. Chougnet,Carlos Julio Montoya,Maria Teresa Rugeles

Over-Expression of Leptin Receptors in Hypothalamic POMC Neurons Increases Susceptibility to Diet-Induced Obesity

Kevin M. Gamber, Lihong Huo, Sangdeuk Ha, Joyce E. Hairston, Sarah Greeley, Christian Bj？rb？k

Amoebal Endosymbiont Protochlamydia Induces Apoptosis to Human Immortal HEp-2 Cells

Atsushi Ito,Junji Matsuo,Shinji Nakamura,Asahi Yoshida,Miho Okude,Yasuhiro Hayashi,Haruna Sakai,Mitsutaka Yoshida,Kaori Takahashi,Hiroyuki Yamaguchi

Immunogenic Comparison of Chimeric Adenovirus 5/35 Vector Carrying Optimized Human Immunodeficiency Virus Clade C Genes and Various Promoters

Masaki Shoji,Shinji Yoshizaki,Hiroyuki Mizuguchi,Kenji Okuda,Masaru Shimada

Altered Neural and Behavioral Dynamics in Huntington's Disease: An Entropy Conservation Approach

S. Lee Hong, Scott J. Barton, George V. Rebec

Gene-Expression Signature Predicts Postoperative Recurrence in Stage I Non-Small Cell Lung Cancer Patients

Yan Lu, Liang Wang, Pengyuan Liu, Ping Yang, Ming You

eNOS Protects from Atherosclerosis Despite Relevant Superoxide Production by the Enzyme in apoE？/？ Mice

Padmapriya Ponnuswamy, Angelika Schr？ttle, Eva Ostermeier, Sabine Grüner, Paul L. Huang, Georg Ertl, Ulrich Hoffmann, Bernhard Nieswandt, Peter J. Kuhlencordt

Validation of a New Method for Testing Provider Clinical Quality in Rural Settings in Low- and Middle-Income Countries: The Observed Simulated Patient

Tin Aung, Dominic Montagu, Karen Schlein, Thin Myat Khine, Willi McFarland

Analysis of Global Sumoylation Changes Occurring during Keratinocyte Differentiation

Phillip R. Heaton, Andres Santos, Germán Rosas-Acosta, Van G. Wilson

LPS Regulates SOCS2 Transcription in a Type I Interferon Dependent Autocrine-Paracrine Loop

Jin Hu, DaoHua Lou, Berit Carow, Malin E. Winerdal, Martin Rottenberg, Ann-Charlotte Wikstr？m, Gunnar Norstedt, Ola Winqvist

Coordinated Activity of Ventral Tegmental Neurons Adapts to Appetitive and Aversive Learning

Yunbok Kim, Jesse Wood, Bita Moghaddam

SASqPCR: Robust and Rapid Analysis of RT-qPCR Data in SAS

Daijun Ling

Probing Amphotericin B Single Channel Activity by Membrane Dipole Modifiers

Olga S. Ostroumova,Svetlana S. Efimova,Ludmila V. Schagina

Bone Marrow-Derived Cells from Male Donors Do Not Contribute to the Endometrial Side Population of the Recipient

Irene Cervelló,Claudia Gil-Sanchis,Aymara Mas,Amparo Faus,Jaime Sanz,Federico Moscardó,Gema Higueras,Miguel Angel Sanz,Antonio Pellicer,Carlos Simón

Environmental Factors Affecting the Expression of pilAB as Well as the Proteome and Transcriptome of the Grass Endophyte Azoarcus sp. Strain BH72

Lena Hauberg-Lotte, Hannah Klingenberg, Christian Scharf, Melanie B？hm, J？rg Plessl, Frauke Friedrich, Uwe V？lker, Anke Becker, Barbara Reinhold-Hurek

Metabolic State Determines Sensitivity to Cellular Stress in Huntington Disease: Normalization by Activation of PPARγ

Youngnam N. Jin, Woong Y. Hwang, Chulman Jo, Gail V. W. Johnson

Protein Kinase D1 Maintains the Epithelial Phenotype by Inducing a DNA-Bound, Inactive SNAI1 Transcriptional Repressor Complex

Ligia I. Bastea, Heike D？ppler, Bolanle Balogun, Peter Storz

In vivo Expansion of Na？ve CD4+CD25high FOXP3+ Regulatory T Cells in Patients with Colorectal Carcinoma after IL-2 Administration

Marc Beyer, Beatrix Schumak, Martin R. Weihrauch, Bettina Andres, Thomas Giese, Elmar Endl, Percy A. Knolle, Sabine Classen, Andreas Limmer, Joachim L. Schultze

Early Alterations in Hippocampal Circuitry and Theta Rhythm Generation in a Mouse Model of Prenatal Infection: Implications for Schizophrenia

Guillaume Ducharme, Germaine C. Lowe, Romain Goutagny, Sylvain Williams

Transcriptional Regulation Is a Major Controller of Cell Cycle Transition Dynamics

Alessandro Romanel, Lars Juhl Jensen, Luca Cardelli, Attila Csikász-Nagy

Structure-Function Studies of DNA Binding Domain of Response Regulator KdpE Reveals Equal Affinity Interactions at DNA Half-Sites

Anoop Narayanan, Lake N. Paul, Sakshi Tomar, Dipak N. Patil, Pravindra Kumar, Dinesh A. Yernool

Modeling the Spread of Methicillin-Resistant Staphylococcus aureus in Nursing Homes for Elderly

Farida Chamchod, Shigui Ruan

The Epidermal Growth Factor Receptor Is Involved in Angiotensin II But Not Aldosterone/Salt-Induced Cardiac Remodelling

Smail Messaoudi, An Di Zhang, Violaine Griol-Charhbili, Brigitte Escoubet, Junichi Sadoshima, Nicolette Farman, Frederic Jaisser

CD40-Activated B Cells Can Efficiently Prime Antigen-Specific Na？ve CD8+ T Cells to Generate Effector but Not Memory T cells

Mélissa Mathieu, Natacha Cotta-Grand, Jean-Fran？ois Daudelin, Salix Boulet, Réjean Lapointe, Nathalie Labrecque

Tigers Need Cover: Multi-Scale Occupancy Study of the Big Cat in Sumatran Forest and Plantation Landscapes

Sunarto Sunarto, Marcella J. Kelly, Karmila Parakkasi, Sybille Klenzendorf, Eka Septayuda, Harry Kurniawan

Clinical Pharmacists on Medical Care of Pediatric Inpatients: A Single-Center Randomized Controlled Trial

Chuan Zhang, Lingli Zhang, Liang Huang, Rong Luo, Jin Wen

Plasmid-Cured Chlamydia caviae Activates TLR2-Dependent Signaling and Retains Virulence in the Guinea Pig Model of Genital Tract Infection

Lauren C. Frazer, Toni Darville, Kumar Chandra-Kuntal, Charles W. Andrews, Matthew Zurenski, Margaret Mintus, Yasser M. AbdelRahman, Robert J. Belland, Robin R. Ingalls, Catherine M. O'Connell

The Prosensory Function of Sox2 in the Chicken Inner Ear Relies on the Direct Regulation of Atoh1

Joana Neves, Masanori Uchikawa, Anna Bigas, Fernando Giraldez

miR-16 Targets Transcriptional Corepressor SMRT and Modulates NF-kappaB-Regulated Transactivation of Interleukin-8 Gene

Rui Zhou, Xiaoqing Li, Guoku Hu, Ai-Yu Gong, Kristen M. Drescher, Xian-Ming Chen

Vitamin D Binding Protein and Monocyte Response to 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D: Analysis by Mathematical Modeling

Rene F. Chun, Bradford E. Peercy, John S. Adams, Martin Hewison

The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1high Leukemia

Norio Yamakawa, Kazuko Kaneda, Yusuke Saito, Emi Ichihara, Kazuhiro Morishita

Alternate Estrogen Receptors Promote Invasion of Inflammatory Breast Cancer Cells via Non-Genomic Signaling

Kazufumi Ohshiro, Arnold M. Schwartz, Paul H. Levine, Rakesh Kumar

A Comparative Study of Gene-Expression Data of Basal Cell Carcinoma and Melanoma Reveals New Insights about the Two Cancers

Kun Xu, Xizeng Mao, Minesh Mehta, Juan Cui, Chi Zhang, Ying Xu

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