OALib Journal
  OALib Journal is an all-in-one open access journal (ISSN Print: 2333-9705, ISSN Online: 2333-9721). It accepts a manuscript for the peer-review processing, typesetting, publication and then allocated to one of the 322 subject areas. The article processing charge for publishing in OALib journal is Only $99. For more details, please contact service@oalib.com. Submit now
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Aug 10, 2023Open    Access

Antiviral Theory Might Help to Develop Drug-Resistance-Free Antimalarial Drugs

Gao-De Li
Based on a novel antiviral theory, the reason why a virus can infect its target cells is because the gene expression pattern in the target cells is suitable for viral infection. Therefore, the alteration of the gene expression pattern in target cells means a reduced susceptibility to all viral infections. Analogously, the reason why sporozoites of malaria parasites can infect hepatocytes is because the gene expression pattern in hepatocytes is suitable for sporozoite infection. If a drug could b...
Open Access Library J.   Vol.10, 2023

Feb 09, 2021Open    Access

Bluetongue Virus Infection in Ruminants: A Review Paper

Mateus de Oliveira Vial, Brennda Vitorino Corrêa, Ana Clara Malegoni, Tayná Bolsam da Silva, Lara Cassaro, Luiz Alexandre Moscon, Diogo Almeida Rondon, Clairton Marcolongo Pereira
Bluetongue is an infectious, viral, non-contagious disease, caused by the virus of the genus Orbivirus and family Reoviridae, being transmitted by hematophagous vectors of the genus Culicoides to domestic and wild ruminants. The disease mainly affects sheep. The infection is related to the climatic conditions of high temperatures and high humidity, which favor the proliferation of vectors. The disease is characterized by systemic hemorrhagic viral fever, caused by vascular injury a...
Open Access Library J.   Vol.8, 2021

Mar 05, 2020Open    Access

Problem of the Management of Haemorrhagic Fevers: Experience of Ebola Virus Disease in the Province of North Kivu and Ituri (DR Congo) and the Importance of Early Diagnosis

Criss Koba Mjumbe, Isabelle Kasongo Omba, Benjamain Kabyla Ilunga, Oscar Luboya Nuymbi
Ebola is a serious, often fatal disease with a fatality rate of up to 90%. The short-term objective of this letter to the listeners is to make known the signs of the Ebola virus to the population and to promote the early diagnosis in our environment. We applied an observation of the cases of the Ebola epidemic in our environment. It is not always possible to quickly identify patients with Ebola virus disease. For this reason, it is important that health workers apply the usual precautions to all...
Open Access Library J.   Vol.7, 2020

May 18, 2017Open    Access

Adenoviruses Type D in Patients with Respiratory Tract Infection Symptoms

Naeme Javid, Abdolvahab Moradi, Alireza Mohebbi, Majid Talkhabifard, Mishar Kelishadi, Alijan Tabarraei
Different Human Adenoviruses (HAdV) serotypes are associated with epidemic respiratory infections. The aim of this study was to detect HAdV from patients with respiratory symptoms and typing virus circulating in North of IRAN. Four hundred nasopharyngeal aspirate samples were obtained from patients with respiratory symptoms. Clinical data were collected. After DNA extraction, Polymerase Chain Reaction (PCR) was done for conserved
Open Access Library J.   Vol.4, 2017

Mar 25, 2016Open    Access

Herpes Simplex Virus 1, Cytomegalovirus and Epstein Barr Virus Detection in Patients with Chronic and Aggressive Periodontitis

Harold H. Hernández, Andreína S. Fernandes, Laura A. Escalona, María Correnti
Recent investigations suggest that the viruses of the family Herpesviridae are associated with periodontal disease, demonstrating a possible association with the presence of Human Cytomegalovirus (HCMV), Herpes Simplex Virus 1 (HSV-1) and Epstein Barr Virus (EBV) in periodontal tissues. Aim: To analyze the association between the presence of HSV-1, HCMV and EBV in patients with chronic or aggressive periodontitis. Methods: Crevicular fluid samples were collected from 11 patients with aggressive ...
Open Access Library J.   Vol.3, 2016

Feb 26, 2016Open    Access

Viral Gastroenteritis among Children under 5 Years in Dutsinma Local Government Area, Katsina State, North-West Nigeria, West Africa

Gnimintakpa Joseph, Adejo Godwin
Rotaviruses and adenoviruses conjointly form the leading cause of epidemic gastroenteritis in developed and developing countries. The prevalence of this array of human viral pathogens in under five years children of Dustin-ma Local Government Area of Katsina State, North-west Nigeria was investigated on diarrheal stool samples of 152 patients of acute viral gastroenteritis by Reverse Transcription Polymerase Chain Reaction (RT-PCR) as approved by the state committee on ethics after parental agre...
Open Access Library J.   Vol.3, 2016

Aug 27, 2015Open    Access

The Significance of Procalcitonin and C-Reactive Protein in Diagnostic Tests for Respiratory Adenovirus Infections in Children

Wolfgang Kunze, Thorsten Klemm, Jan-Peter Streidl
Background: This study aims to answer the question if procalcitonin tests allow distinguishing bacterial from AdV infections in cases in which acute phase values are significantly elevated. Methods: 40 patients of infant and toddler age were divided into two patient groups (n = 23) and (n = 17) for comparison based on PCT 0.5 μg/L. AdV was determined by polymerase-chain-reaction. Results: The PCT value in Group 1 is 0.21 ± 0.12 μg/L, median 0.2, and 1.56 ± 1.07 μg/L, median 1.3 (p = 0.000...
Open Access Library J.   Vol.2, 2015

Jul 22, 2014Open    Access

Bell’s Palsy “Laqwa”: Survey Based Study

Safila Naveed, Hafiza Nimal Tasleem

Bell’s palsy is an acute disorder of the facial nerve in which full or partial loss of the movement on one side of face occurs. The Bell’s palsy gets better without treatment in most, but not all, people. Swelling or inflammation of this nerve can also cause Bell’s palsy. Physical therapies exercise, massage, laser, electrotherapy and thermotherapy used to hasten recovery. Many people who have a Bell’s palsy at first think that they have a stroke. Bell’s

Open Access Library J.   Vol.1, 2014


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