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Apr 11, 2025Open Access
Background and objectives: Lupus nephritis is one of the most common complications of Systemic Lupus Erythematosus, due to the accumulation of immunocomplexes of antigens and antibodies at the renal level. In the laboratory, serum anti-C1q antibody levels have become an important tool for monitoring and management of this disease. This study evidences the levels of anti-C1q as a marker of renal involvement in patients with SLE. Patients and methods: The study wa...
Jan 09, 2025Open Access
Background: Systemic lupus erythematosus (SLE) and Sjögren Syndrome (SS) are chronic autoimmune diseases with a spectrum of clinical and serological presentations. Multiple myeloma (MM) has been demonstrated in the course of these diseases. However, the occurrence of MM in young patients under 30 years with SLE and SS has never been described. Case presentation: We describe the first documented case of a 27-year-old Senegalese woman who presented MM after t...
Oct 31, 2024Open Access
Background: In 2019, PRINTO proposed new classification criteria for Juvenile idiopathic arthritis (JIA) that make the classification more homogeneous than ILAR criteria. Objectives: We aimed to describe the profile of JIA in Senegal according to these new classification criteria and compare the findings to other populations. Methods: We conducted a mixed cohort study by reviewing the medical records of patients diagnosed with JIA with an age of...
Apr 20, 2023Open Access
Burkholderia pseudomallei is an unusual causative organism of infective endocarditis. We present a case of Melioidosis mitral valve endocarditis with dissemination to the liver and kidney in a young woman with underlying SLE with lupus nephritis. Despite the delay in reaching a diagnosis, the patient was successfully treated with intravenous Ceftazidime and oral trimethoprim-sulfamethoxazole and was discharged well. The identification of the specific aetiologic organism is important for t...
Nov 17, 2022Open Access
Adhesive capsulitis (AC) of the shoulder is a painful condition in which active and passive range of motion (ROM) of the shoulder becomes restricted. Severe pain and ROM restriction may last approximately 1 to 3 years with incomplete resolution leading to an impairment of daily living and professional activities and quality of life with a consequent social and economic burden. Since health care services have been shifted to the fight against the deadly coronavirus disease 2019 (COVID-19), a mini...
Nov 08, 2022Open Access
Antisynthetase syndrome (AS) is a rare systemic autoimmune disease characterized by the presence of anti-tRNA synthetase antibodies. Cardiac involvement (pericarditis) in AS is uncommon. Here, we present the case of a young African female who presented with acute pericarditis as an initial manifestation of AS. She was diagnosed with anti-Jo1 antisynthetase syndrome based on Connors criteria. Treatment with corticosteroids and azathioprine improved symptoms. This case underlines the importance fo...
Nov 07, 2022Open Access
Orofacial manifestations occur frequently in rheumatic diseases and usually represent early signs of disease or of its activity that are still neglected in clinical practice. Among the autoimmune rheumatic diseases with potential for oral manifestations, rheumatoid arthritis (RA), inflammatory myopathies (IM), systemic sclerosis (SSc), systemic lupus erythematosus (SLE), relapsing polychondritis (RP) and Sjögren’s syndrome (SS) can be cited. Signs and symptoms such as oral hyposalivation, x...
Oct 11, 2022Open Access
Introduction: Systemic sclerosis (SSc) is a chronic autoimmune disease of the connective tissue marked by fibrosis, which can have different clinical forms and variations in the number of cases between populations. Objective: Analyze the clinical and epidemiological characteristics of patients, the profile of autoantibodies and mortality from SSc at the Universitary Hospital of Teresina, PI, Brazil. Methods: Review of electronic medical records, with results presented in tables of absolute and r...
Jul 07, 2021Open Access
Impaired visual acuity was the first presentation in a 32-year-old lady who was subsequently diagnosed as systemic lupus erythematosus (SLE) at 6 mon- ths post delivery. We report a rare case of Purtscher-like retinopathy in a SLE patient, its clinical presentation, funduscopic findings and response to steroid, panretinal photocoagulation and mycophenolate mofetil (MMF).
Nov 23, 2020Open Access
Objective: To observe and analyze the changes in muscle mass in patients with Sjogren’s syndrome and sarcopenia. Methods: From October 2016 to December 2018, the muscle mass of 31 female patients with Sjogren’s syndrome who underwent DXA testing in Linyi City People’s Hospital was tested, and the changes in muscle mass of patients with Sjogren’s syndrome were investigated. Results: The incidence of decreased skeletal muscle mass in patients with Sjogren’s syndrome was lower. The upper and lower ...
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