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Apr 11, 2025Open    Access

Anti-C1q Antibodies as Markers of Renal Involvement in Patients with Systemic Lupus Erythematosus, Bolivar City, Venezuela

Abimael Esaul Gómez-Sifontes,Jesus Alejandro Diaz-Tablero,Yvan Jose García Gonzalez Rodriguez
Background and objectives: Lupus nephritis is one of the most common complications of Systemic Lupus Erythematosus, due to the accumulation of immunocomplexes of antigens and antibodies at the renal level. In the laboratory, serum anti-C1q antibody levels have become an important tool for monitoring and management of this disease. This study evidences the levels of anti-C1q as a marker of renal involvement in patients with SLE. Patients and methods: The study wa...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112987


Jan 09, 2025Open    Access

Multiple Myeloma in Young African Woman with Systemic Lupus Erythematosus and Sjögren Syndrome: A Case Report

Mounib M. Sabounji,Coumba Ndiaye
Background: Systemic lupus erythematosus (SLE) and Sjögren Syndrome (SS) are chronic autoimmune diseases with a spectrum of clinical and serological presentations. Multiple myeloma (MM) has been demonstrated in the course of these diseases. However, the occurrence of MM in young patients under 30 years with SLE and SS has never been described. Case presentation: We describe the first documented case of a 27-year-old Senegalese woman who presented MM after t...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112574


Oct 31, 2024Open    Access

Application of the 2019 PRINTO Classification Criteria for Juvenile Idiopathic Arthritis at a Tertiary Hospital in Senegal, West Africa

Mounib M. Sabounji,Babacar Diakhate,Aïssatou Ndiaye,Saïdou Diallo
Background: In 2019, PRINTO proposed new classification criteria for Juvenile idiopathic arthritis (JIA) that make the classification more homogeneous than ILAR criteria. Objectives: We aimed to describe the profile of JIA in Senegal according to these new classification criteria and compare the findings to other populations. Methods: We conducted a mixed cohort study by reviewing the medical records of patients diagnosed with JIA with an age of...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1112314


Apr 20, 2023Open    Access

Melioidosis a Rare Cause of Infective Endocarditis: A Case Report

Chun Kiat Ng, Anuradha P. Radhakrishnan
Burkholderia pseudomallei is an unusual causative organism of infective endocarditis. We present a case of Melioidosis mitral valve endocarditis with dissemination to the liver and kidney in a young woman with underlying SLE with lupus nephritis. Despite the delay in reaching a diagnosis, the patient was successfully treated with intravenous Ceftazidime and oral trimethoprim-sulfamethoxazole and was discharged well. The identification of the specific aetiologic organism is important for t...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110004


Nov 17, 2022Open    Access

Management of Adhesive Capsulitis of the Shoulder: Recommendation for Home Exercises Program during COVID-19 Pandemic

Amine Kalai, Mohamed Guedria, Amr Chaabeni, Zohra Ben Salah Frih, Anis Jellad
Adhesive capsulitis (AC) of the shoulder is a painful condition in which active and passive range of motion (ROM) of the shoulder becomes restricted. Severe pain and ROM restriction may last approximately 1 to 3 years with incomplete resolution leading to an impairment of daily living and professional activities and quality of life with a consequent social and economic burden. Since health care services have been shifted to the fight against the deadly coronavirus disease 2019 (COVID-19), a mini...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109443


Nov 08, 2022Open    Access

Acute Pericarditis as the Initial Manifestation of Antisynthetase Syndrome: A Case Report

Mounib M. Sabounji, Aissatou Ndiaye, Sekouba Sagna
Antisynthetase syndrome (AS) is a rare systemic autoimmune disease characterized by the presence of anti-tRNA synthetase antibodies. Cardiac involvement (pericarditis) in AS is uncommon. Here, we present the case of a young African female who presented with acute pericarditis as an initial manifestation of AS. She was diagnosed with anti-Jo1 antisynthetase syndrome based on Connors criteria. Treatment with corticosteroids and azathioprine improved symptoms. This case underlines the importance fo...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109451


Nov 07, 2022Open    Access

Temporomandibular Joint Disorder in Systemic Sclerosis: A Case Report

Maria do Socorro Teixeira Moreira Almeida, Mariana Lima Mousinho Fernandes, Thais Cristina Araújo Moreira
Orofacial manifestations occur frequently in rheumatic diseases and usually represent early signs of disease or of its activity that are still neglected in clinical practice. Among the autoimmune rheumatic diseases with potential for oral manifestations, rheumatoid arthritis (RA), inflammatory myopathies (IM), systemic sclerosis (SSc), systemic lupus erythematosus (SLE), relapsing polychondritis (RP) and Sjögren’s syndrome (SS) can be cited. Signs and symptoms such as oral hyposalivation, x...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109434


Oct 11, 2022Open    Access

Analysis of Auto Antibodies, Mortality and Epidemiology of Hospitalized Patients for Systemic Sclerosis in a University Hospital

Maria do Socorro Teixeira Moreira Almeida, Liana Nara Oliveira Moreira
Introduction: Systemic sclerosis (SSc) is a chronic autoimmune disease of the connective tissue marked by fibrosis, which can have different clinical forms and variations in the number of cases between populations. Objective: Analyze the clinical and epidemiological characteristics of patients, the profile of autoantibodies and mortality from SSc at the Universitary Hospital of Teresina, PI, Brazil. Methods: Review of electronic medical records, with results presented in tables of absolute and r...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109295


Jul 07, 2021Open    Access

Purtscher-Like Retinopathy as First Presentation in a Newly Diagnosed Systemic Lupus Erythematosus Patient and Its Response to Treatment

Ng Chun Ruh, She Poh Fong, Ong Ming Jew, Loh Yet Lin
Impaired visual acuity was the first presentation in a 32-year-old lady who was subsequently diagnosed as systemic lupus erythematosus (SLE) at 6 mon- ths post delivery. We report a rare case of Purtscher-like retinopathy in a SLE patient, its clinical presentation, funduscopic findings and response to steroid, panretinal photocoagulation and mycophenolate mofetil (MMF).
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107485


Nov 23, 2020Open    Access

Analysis of 31 Cases of Female Sjogren’s Syndrome Patients with Changes in Muscle Mass

Yubao Zhang, Meng Wang
Objective: To observe and analyze the changes in muscle mass in patients with Sjogren’s syndrome and sarcopenia. Methods: From October 2016 to December 2018, the muscle mass of 31 female patients with Sjogren’s syndrome who underwent DXA testing in Linyi City People’s Hospital was tested, and the changes in muscle mass of patients with Sjogren’s syndrome were investigated. Results: The incidence of decreased skeletal muscle mass in patients with Sjogren’s syndrome was lower. The upper and lower ...
Open Access Library J.   Vol.7, 2020
Doi:10.4236/oalib.1106872


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