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Feb 03, 2026Open    Access

Characterization of Species of the Anopheles gambiae Complex in Kintele and Djoumouna (Brazzaville, Congo)

Grace Odera Tainsie Nianga Bikouta,Dia Ibrahima,Patrick Bitsindou,Mireille Belle Mbou Okassa,Valentin Dibangou,Mawlouth Diallo,Arsene Lenga
The effectiveness of implementing vector control strategies for malaria is assessed by monitoring vector dynamics and their role in malaria transmission. This study was carried out between September 2016 and August 2017 in Kintele and Djoumouna, and in August 2019 in Djoumouna alone. The objective of this study was to identify the Anopheles species involved in malaria transmission, their dynamics over time, and to evaluate the entomological indices based on the types of bedrooms investigated. An...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114734


Oct 11, 2025Open    Access

Diagnostic Correlation of Antinuclear Antibodies Detected by ELISA and Indirect Immunofluorescence in Patients Attending a Private Laboratory in Ciudad Bolívar, Venezuela

Abimael E. Gómez-Sifontes,Jesús E. T. García Terrizzi,Anthony R. Cremona-Dávila,Carmen Rodríguez,Gey E. Partidas-Uribe,Carmen G. Cuba-Garrido,Arnaldo R. Saavedra-Duque
Background and Objectives: Antinuclear antibodies (ANA) are immunoglobulins directed against nuclear and cytoplasmic components of autologous cells, reflecting the loss of immunological tolerance and having a multifactorial origin. This study relates antinuclear antibodies by ELISA and indirect immunofluorescence (IFA) in patients attended at Ciudad Bolívar, Venezuela 2022. Patients and Methods: A descriptive and cross-sectional study was conducted to relate antinuclear antibodies by ELISA and i...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1114221


Sep 28, 2025Open    Access

Autoimmune Myasthenia Gravis: Diagnosis and Management in a Young Patient Seen for Consultation at the National Reference General Hospital of N’Djamena (Chad)

Adoum Hamad Zenal Abidine,Boubacar Soumaila,Madjirabé Christian,Mht Alkher Ousmane,Guelngar Othon Carlos,Alhadj Mht Moustapha,Adoum Hamat Kaltam,Adoum Hamat Alfaris,Tahir Aiba,Abdel-Madjid Zakaria Zakaria,Toure Kamadore
Introduction: Myasthenia gravis is a neuromuscular junction disorder characterized by fatigability, muscle weakness affecting the oculomotor, bulbar, and skeletal muscles, worsening with exertion and resolving at rest. It is an autoimmune neurological disease that can be life-threatening due to respiratory muscle damage. Clinical Case: This is a 20-year-old male XL patient with no particular history who presents with muscle fatigue during exercise associated wit...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1113994


Sep 28, 2025Open    Access

Exploring Demographic and Clinical Trends in Postural Orthostatic Tachycardia Syndrome (POTS): Insights from Public Database Analysis

Vasisht Karri,Dennis Wolff
Postural Orthostatic Tachycardia Syndrome (POTS) is a heterogeneous disorder characterized by an excessive increase in heart rate upon standing without significant orthostatic hypotension. While recognized as a major autonomic dysfunction, its epidemiology and treatment patterns remain underexplored on a population level. This study utilizes two public health databases—the National Inpatient Sample (NIS) and the National Health and Nutrition Examination Survey (NHANES)—to analyze demographic dis...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1114134


Sep 18, 2025Open    Access

Cardiac Manifestations during Systemic Lupus Erythematosus at Conakry University Hospital (Guinea)

Thierno Amadou Wann,Djibril Sylla,Amadou Kake,Mamadou Bassirou Bah,Mamadou Aliou Kante,Mamadou Diakhaby,Mamadou Lamine Yaya Bah
Introduction: Systemic lupus erythematosus (SLE) is a non-organ-specific disease. Cardiac involvement is present in 25% - 82% of cases and represents one of the leading causes of mortality. Materials and Methods: Systemic lupus erythematosus (SLE) is a non-organ-specific disease. Cardiac involvement is present in 25% - 82% of cases and represents one of the leading causes of mortality. We included all patients with lupus who met at least four criteria of the American College of Rheumatology (ACR...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1114118


Aug 11, 2025Open    Access

Humoral Immunity in Pediatric Patients with Recurrent Infections: A Study in the Pediatric II Service of the “Ruíz y Páez” University Hospital Complex, Ciudad Bolívar, Bolívar State, Venezuela

Abimael E. Gómez-Sifontes,Eddyz Emerson Mejías-Pereira,Pedro Alejandro Tabata-Rodríguez
Background: Infectious processes are the leading cause of pediatric consultation, and recurrent or severe infections may indicate primary immunodeficiencies (PIDs), which comprise more than 484 rare diseases affecting the immune response. The nature and severity of infections depend on the component of the immune system affected, with defects in humoral immunity being a frequent cause of severe respiratory infections. Evaluation of blood immunoglobulin (Ig) levels is essential for the identifica...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1113706


Apr 11, 2025Open    Access

Anti-C1q Antibodies as Markers of Renal Involvement in Patients with Systemic Lupus Erythematosus, Bolivar City, Venezuela

Abimael Esaul Gómez-Sifontes,Jesus Alejandro Diaz-Tablero,Yvan Jose García Gonzalez Rodriguez
Background and objectives: Lupus nephritis is one of the most common complications of Systemic Lupus Erythematosus, due to the accumulation of immunocomplexes of antigens and antibodies at the renal level. In the laboratory, serum anti-C1q antibody levels have become an important tool for monitoring and management of this disease. This study evidences the levels of anti-C1q as a marker of renal involvement in patients with SLE. Patients and methods: The study wa...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112987


Mar 17, 2025Open    Access

The Role of Human Herpesvirus-Encoded MicroRNA in Host Virus Interaction

Bandana Pandey
Human Herpesviruses (HHVs) are a group of large DNA viruses that can establish lifelong infections in their hosts. They achieve this by switching between two phases: the lytic phase, where the virus actively replicates, and the latent phase, where the virus remains dormant but can reactivate later. A key factor in this process is microRNAs (miRNAs)—small, non-coding RNA molecules that regulate gene expression. In human cells, miRNAs play a crucial role in controlling various biological processes...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1113043


Jul 26, 2024Open    Access

COVID-19 Vaccine Acceptance and Hesitancy among Healthcare Workers at a Teaching Hospital in Zambia: Findings and Implications

Steward Mudenda,Banji Moonga,Maisa Kasanga,Victor Daka,Ngoni Veddie Muzondo,Ruth Lindizyani Mfune,Shafiq Mohamed,Nathan Mugenyi,Manal Hadi Ghaffoori Kanaan,Billy Chabalenge
Introduction: The coronavirus disease (COVID-19) vaccines provided renewed hope in the fight against the COVID-19 pandemic. To promote extensive vaccination coverage, it is imperative to assess the inclination towards receiving vaccines and examine the influencing factors among healthcare workers (HCWs). This study evaluated COVID-19 vaccine acceptance and hesitancy among HCWs at a Teaching Hospital in Zambia. Materials and Methods: This cross-sectional study wa...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111827


May 11, 2024Open    Access

Ultrasound-Guided Stellate Ganglion Block on Sleep Disorders in Patients Recovered from COVID-19

Pu Chen,Yuping Hu,Nana Zhang
Objective: This study aimed to observe the therapeutic effect of ultra-sound-guided stellate ganglion block (U-SCG) on sleep disorders in pa-tients who have recovered from COVID-19. Methods: A retrospective analysis was conducted on 39 patients with post-COVID-19 sleep disorders treated at the Department of Anesthesiology, Fourth Affiliated Hospital of Nanjing Medical University. The treatment involved a 7-day course of U-SCG, and the improvement in sleep was as...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111525


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