OALib Journal
  OALib Journal is an all-in-one open access journal (ISSN Print: 2333-9705, ISSN Online: 2333-9721). It accepts a manuscript for the peer-review processing, typesetting, publication and then allocated to one of the 322 subject areas. The article processing charge for publishing in OALib journal is Only $99. For more details, please contact service@oalib.com. Submit now
               Articles    |    Aims & Scope    |    Instructions for Author     |    Editorial Board     |    Publishing Price    |    Indexing             


Oct 26, 2021Open    AccessArticle

Seroprevalence and Risk Factors of the Helicobacter pylori Infection in Bukavu City in the Democratic Republic of Congo

Patrick de Jésus Ngoma, Benjamin Longo-Mbenza, Evariste Tshibangu-Kabamba, Bellarmin Matungo, David Lupande, Christian Malu, Pitchou Kengibe, Antoine Tshimpi, René Fiasse, Dahma Hafid, Jeff Kabinda, Yoshio Yamaoka, Aliocha Nkodila, Yvette Mienje
The prevalence of Helicobacter pylori (H. pylori) infection is high in Africa. However, local surveys are still needed to be conducted for filling up the gap existing in understanding the epidemiological situation of the infection within the continent. This study aimed to assess the seroprevalence of H. pylori and its determinant factors in Bukavu, the capital city of Southern Kivu Province in Eastern part of the Democratic Republic of Congo (DRC). A cross-sectional communit...
Open Access Library J. Vol.8, 2021

Sep 18, 2021Open    AccessArticle

Electrophoresis of Proteins in the Biochemistry Laboratory of the University Hospital of Brazzaville

Fylla Koumou Onanga, Jeanne Kibah Gambomi, Monde Ikia, Rod Ibara-Okabande, Barnes Yoyo, C. R. Dobhat-Doukakini, Reine F. Eboka-Loumingou Sakou, Childerick Lekana, Aliocha Natuhoyila Nkodila, Etienne Mokondjimobé, Benjamin Longo Mbenza
Background and aim: The electrophoresis of serum proteins is one of the examinations requested at the Biochemistry laboratory, with a view to highlight various pathologies. The aim of our study is to analyze the different electrophoretic profiles encountered in our current practice. Methods: This is a retrospective study of 350 serum samples collected at the biochemistry laboratory of the University Hospital Center (CHU) of Brazzaville. The electrophoresis of serum proteins was carried out on a ...
Open Access Library J. Vol.8, 2021

Jun 28, 2021Open    AccessArticle

Wnt5a Role in Cisplatin Effect and Selectivity Augmentation in Cancer Therapy

Waleed O. Atta, Ahmed Z. Abdel Azeiz
Wnt5a is a representative protein ligand that activates a beta catenin independent pathway in Wnt signaling in cancer progression and spread in the palmitoylated form. So that its synthesis is augmented through promotion of its gene transcription in the malignant cells. Cisplatin is an important chemotherapeutic drug used in treatment of different types of advanced cancer. However, its usage is limited due to severe dose-limiting side effects, due to the lack of targeting therapy of cisplatin. O...
Open Access Library J. Vol.8, 2021

May 28, 2021Open    AccessArticle

Probing of Interaction between Alogliptin Benzoate and Human Serum Albumin Using Multi-Spectral Methods and Molecule Docking Technique

Nan Zhang, Jianbo Chen, Zhuowei Han
The interaction of alogliptin benzoate with human serum albumin had been characterized under physiological conditions using multi-spectral methods and molecular docking technique. The work presented in this paper focused on the interaction mechanism, the conformational changes of HSA and the binding sites of alogliptin benzoate with human serum albumin. The binding distance, binding constants, the number of binding sites and the binding forces had been investigated through fluorescence and spect...
Open Access Library J. Vol.8, 2021

Dec 31, 2020Open    AccessArticle

Selection and Analysis of Protein Circular Dichroism Spectra Using an Expansion of Spectral Factors

David A. Haner
Techniques are presented to develop spectroscopic factors directly from circular dichroism spectra of proteins using singular value decomposition on a small database. Four spectra of maximum spectral variability are chosen to characterize the database. These selected protein spectra are then factored by singular values into component spectra, which are collected as comparative vector characteristics used as factor fractions. The necessary standardization for comparison is achieved using unit nor...
Open Access Library J. Vol.7, 2020

Nov 27, 2020Open    AccessArticle

Response Surface Methodology to Optimize Degradation on Phenol by Pseudomonas stutzeri ZH-1

Yong Yan, Qingping Hu
In order to obtain the optimal conditions for the degradation of phenol by Pseudomonas stutzeri ZH-1, based on the single factor experiment, the Box Behnken design test of Response Surface Method was used. Four variables of glucose concentration (0.4, 0.6, 0.8 g/L), inoculation concentration (3%, 5%, 7%), pH (6, 7, 8) and temperature (35°C, 37.5°C, 40°C) were used to identify the significant effects and interactions in the batch studies. A second order polynomial regression mo...
Open Access Library J. Vol.7, 2020

Oct 29, 2020Open    AccessArticle

Evaluation of the Protective Effect of Citrullus lanatus (Water Melon) Fruit-Parts Extracts on the Liver of Acetaminophen-Intoxicated Albino Rats

M. O. Enemali, M. E. Asogwa, C. C. Nweze, G. S. Haruna, A. U. Ijeomah
There is always the need to study the bioactive components present in the various parts of edible fruits. This will go a long way to providing an idea of its potential biological benefits when consumed. The current study evaluated the protective effect of C. lanatus fruit’s endocarp/exocarp, mesocarp and seed extracts on the liver of albino rats. The qualitative and quantitative phytochemical analysis was also done following standard methods. The albino rats were divided into nine groups of five...
Open Access Library J. Vol.7, 2020

Jun 24, 2020Open    AccessArticle

Study on Preparation of Bio-Oil from Wheat Straw by Hydrothermal Liquefaction

Dongyu Guo, Jun Wang
Wheat straw is an ideal green renewable resource, which is widely used as fertilizers, feedstuffs, edible funguses, industrial raw materials and fuels. Hydrothermal liquefaction of biomass that works under normal or slightly pressurized conditions results in higher oil quality. We summarize the technical principles of hydrothermal liquefaction, analyze the difficulties and problems in the utilization of various technologies, and put forward the development trend of promoting the application of b...
Open Access Library J. Vol.7, 2020

May 29, 2020Open    AccessArticle

Effects of Light on Saccharide Wastewater Treatment and Resource Recovery by Proteiniphilum acetatigenes PSB-W

Qingping Hu, Xiaoli Gao
Photosynthetic bacteria (PSB) wastewater treatment is a new method with great resource recovery potential. In order to improve the biomass and valuable resources of bacteria in the wastewater treatment of photosynthetic bacteria, the effects of different light conditions on the efficiency of Proteiniphilum acetatigenes PSB-W in the treatment of sugar wastewater and the production of bacteria and carotenoids in the wastewater were analyzed from three aspects of light source, light intensity and l...
Open Access Library J. Vol.7, 2020

Mar 17, 2020Open    AccessArticle

Assessment of Serum Electrolyte Levels & HbA1C Levels among Type 2 Diabetic Sudanese Patients with Macrovascular Complications in Khartoum State

Ragda Hafaz Ramadan, Abdulmwla Muhammed Abdullah
Background: Recently epidemiological studies have shown that type 2 diabetes mellitus is great a risk factor for cardiovascular mortality. Electrolyte abnormalities are commonly encountered in chronic diabetes mellitus type 2 patients. Aim: The aim of this study was to estimate serum electrolyte levels & HbA1C levels among Sudanese diabetic Patients with macrovascular complications in Khartoum State, Sudan. Materials & Methods: In this case, control hospital based study conducted in Khartoum sta...
Open Access Library J. Vol.7, 2020


Contact Us



微信:OALib Journal