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International Journal of Medicinal Chemistry

ISSN Print: 2090-2069

ISSN Online:

主页: http://www.hindawi.com/journals/ijmc/

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Syntheses and Biological Activity of Some Derivatives of C-9154 Antibiotic

Isaac Asusheyi Bello,George Iloegbulam Ndukwe,Joseph Olorunju Amupitan,Rachael Gbekele Ayo,Francis Oluwole Shode

Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N-Diethyl-Substituted Amido Moieties

Olayinka O. Ajani,Oluwole B. Familoni,Feipeng Wu,Johnbull O. Echeme,Zheng Sujiang

Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors

Stéphane L. Raeppel,Frédéric Gaudette,Hannah Nguyen,Normand Beaulieu,James Wang,Christiane Maroun,Jeffrey M. Besterman,Arkadii Vaisburg

Aurones: A Promising Heterocyclic Scaffold for the Development of Potent Antileishmanial Agents

Marina Roussaki,Sofia Costa Lima,Anna-Maria Kypreou,Panagiotis Kefalas,Anabela Cordeiro da Silva,Anastasia Detsi

AutoGPA: An Automated 3D-QSAR Method Based on Pharmacophore Alignment and Grid Potential Analysis

Naoyuki Asakawa,Seiichi Kobayashi,Junichi Goto,Noriaki Hirayama

Development of 5-Substituted N-Methylmorphinan-6-ones as Potent Opioid Analgesics with Improved Side-Effect Profile

Helmut Schmidhammer,Mariana Spetea

In Silico Inhibition Studies of Jun-Fos-DNA Complex Formation by Curcumin Derivatives

Anil Kumar,Utpal Bora

Secondary Structural Preferences of Some Antibacterial Cyclooctapeptides in the Presence of Calcium(II)

Tarshona Stevens,Nykia McNeil,Xiuli Lin,Maria Ngu-Schwemlein

Synthesis, Characterization, and Biological Evaluation of Some New Functionalized Terphenyl Derivatives

Seranthimata Samshuddin,Badiadka Narayana,Balladka Kunhanna Sarojini,Divya N. Shetty

A DFT and Semiempirical Model-Based Study of Opioid Receptor Affinity and Selectivity in a Group of Molecules with a Morphine Structural Core

Tamara Bruna-Larenas,Juan S. Gómez-Jeria

A DFT and Semiempirical Model-Based Study of Opioid Receptor Affinity and Selectivity in a Group of Molecules with a Morphine Structural Core

Tamara Bruna-Larenas,Juan S. Gómez-Jeria

Secondary Structural Preferences of Some Antibacterial Cyclooctapeptides in the Presence of Calcium(II)

Tarshona Stevens,Nykia McNeil,Xiuli Lin,Maria Ngu-Schwemlein

Synthesis, Characterization, and Biological Evaluation of Some New Functionalized Terphenyl Derivatives

Seranthimata Samshuddin,Badiadka Narayana,Balladka Kunhanna Sarojini,Divya N. Shetty,Nalilu Suchetha Kumari

In Silico Inhibition Studies of Jun-Fos-DNA Complex Formation by Curcumin Derivatives

Anil Kumar,Utpal Bora

Differential Effect of the Dopamine Agonist ( )-7-Hydroxy-2-(N,N-di-n-propylamino) Tetralin (7-OH-DPAT) on Motor Activity between Adult Wistar and Sprague-Dawley Rats after a Neonatal Ventral Hippocampus Lesion

Sonia Guzmán-Velázquez,Linda Garcés-Ramírez,Gonzalo Flores,Fidel De La Cruz,Sergio R. Zamudio

Pyrazolo Derivatives as Potent Adenosine Receptor Antagonists: An Overview on the Structure-Activity Relationships

Siew Lee Cheong,Gopalakrishnan Venkatesan,Priyankar Paira,Ramasamy Jothibasu,Alexander Laurence Mandel,Stephanie Federico,Giampiero Spalluto,Giorgia Pastorin

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors

Ashraf H. Abadi,Jochen Lehmann,Gary A. Piazza,Mohammad Abdel-Halim,Mohamed S. M. Ali

Pharmacophore Modelling and Synthesis of Quinoline-3-Carbohydrazide as Antioxidants

Mustapha El Bakkali,Lhassane Ismaili,Isabelle Tomassoli,Laurence Nicod,Marc Pudlo,Bernard Refouvelet

Studies on 16 -Hydroxylation of Steroid Molecules and Regioselective Binding Mode in Homology-Modeled Cytochrome P450-2C11

Hamed I. Ali,Morio Yamada,Yukihisa Fujita,Mitsuko Maeda,Eiichi Akaho

Design, Synthesis, and Antifungal Activity of New α-Aminophosphonates

Zahra Rezaei,Soghra Khabnadideh,Kamiar Zomorodian,Keyvan Pakshir,Setareh Nadali,Nadia Mohtashami,Ehsan Faghih Mirzaei

Inhibition of RNA Helicases of ssRNA+ Virus Belonging to Flaviviridae, Coronaviridae and Picornaviridae Families

Irene Briguglio,Sandra Piras,Paola Corona,Antonio Carta

Synthesis of the Nakanishi Ring-Locked Retinoid

Jamie B. C？té,Tan D. Quach,Andrey P. Demenev,David S. Garvey,Judd M. Berman

Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells

S. Lakshmi,G. Padmaja,P. Remani

The Discovery of Novel Selective D1 Dopaminergic Agonists: A-68930, A-77636, A-86929, and ABT-413

Yvonne Connolly Martin

Evaluation of a Set of C9 N-acyl Neu5Ac2en Mimetics as Viral Sialidase Selective Inhibitors

Sadagopan Magesh,Nongluk Sriwilaijaroen,Setsuko Moriya,Hiromune Ando,Taeko Miyagi,Yasuo Suzuki,Hideharu Ishida,Makoto Kiso

Dopamine Receptors and Parkinson's Disease

Shin Hisahara,Shun Shimohama

Comparative Study on the MDR Reversal Effects of Selected Chalcones

A. B. Ivanova,D. I. Batovska,I. T. Todorova,B. A. Stamboliyska,J. Serly,J. Molnar

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