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Feb 05, 2025Open    Access

Acute Toxicity of Ciprofloxacin, Norfloxacin and Florfenicol to Misgurnus anguillicaudatus

Zhen Wang,Jinqing Wang,Yan Chen,Xiaorui Yu,Xiaohui Ni,Jincheng Wang,Haiyan Sun,Yuzhuo Dai,Zeyu Li,Zhanyu Wang
This study was conducted to investigate the acute toxic effects of ciprofloxacin, norfloxacin and florfenicol, which are widely used antibacterial drugs, on loach. Through a well-planned experimental design, we systematically monitored the physiological and behavioral characteristics of loach under different drug concentrations and exposure time, and evaluated the toxic effects of these drugs. Under specific test conditions, i.e. water temperature is maintained at (10.0 ± 2.0)℃, and the pH value...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112850


Jan 08, 2025Open    Access

Advancement in Nanoparticle-Based NIRF Probes for Precision Visualization in Oncology

Michael Adeniyi
Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, hold significant promise for in vivo visualization, due to their ability to access biological tissues and significantly reduce background interference from autofluorescence. Nanoparticles integrated with IR dyes have undergone extensive investigation regarding their pharmacokinetic behavior, including biodistribution patterns and clearance mechanisms. These nanoparticles exhibit a remarkable ability to prefere...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112471


Jul 31, 2024Open    Access

Measurement of Ankle Joint Kinematics Using IMUs during Countermovement Jumps and Lateral Skater Jumps

Ifeoluwa Olawore
This study compared Inertial Measurement Unit (IMU) and Optical Motion Capture (OMC) systems in measuring peak ankle angles and Range of Motion (ROM) during Countermovement Jumps (CMJ) and Lateral Skater Jumps (LSJ). Data during these agility movements were analyzed and the ankle angles in pitch, roll, and yaw for the IMU were determined using algorithms which integrated gyroscope data, aligned it with foot flat reference, and fused it with accelerometer-derived inclination angles using a comple...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111809


Jul 25, 2024Open    Access

Smartphone Oximeter SpO2 Integrated Measurement

Yahweh Van Ram Sri
Smartphone-based Oximetry device as early healthcare detection is a technological frontier. Smartphone oximetry devices offer a convenient method for remote SpO2 monitoring and early detection of critical health issues, especially during pandemics when vital indicators are necessary. Rising healthcare demands, and the COVID-19 pandemic are recent causes necessitating the prevalence for accessible early detection tools. This research investigates smartphone oximetry device as a conveni...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111580


Jul 03, 2024Open    Access

Gold-Based Core@shell Heteronanostructured Materials for Biomedical Engineering Application: Recent Trends & New Perspectives

Déogratias Ntirikwendera,Solange Mukeshimana,Jean Claude Uwamahoro
Core@shell nanoparticles are advanced functional materials with modified properties combined into a single unity leading to their enhanced physico-chemical properties. In biomedical field, bi/tri/or multi-metallic Gold-Based Nanocrystals (GBNCs) and metamaterials, with core@shell heteronanostructures exhibit superior plasmonic properties with a broad range from sensing technology to nanomedicine. In this review paper, we investigated the recent trends of gold nanoparticles with a particular focu...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111603


May 31, 2024Open    Access

Inhibitory Effect of Medicinal Secondary Compounds on Carcinogenic Cell-Lines

Yousef M. Almutairi,Elbert Lewis Myles,Waeel H. Alramadhan,Naif M. Alhawiti
There are various methods used to treat cancer including the use of natural compounds. This paper describes the investigation of the cytotoxic effects of the plant Senna’s secondary compounds when exposed to different types of cancer cells. Cassia angustifolia (senna) is a native plant of Yemen, Somalia and Arabia. It is used medicinally in other parts of the world. The practical experiments carried out aim at showing the rate of growth inhibition of the cancer cells after their exposure to the ...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111593


May 08, 2024Open    Access

Production and Characterization of Keratinase Enzyme from Natural Isolate Bacillus Strains

Aboubacar Sidiki Dansoko
Bacillus sp is microorganism’s species which can produce keratinase enzyme.The enzyme has ability to degrade keratine substrate and it belongs to extraceluler inducible enzyme group. In this study, proteolitic activities of Bacillus strains isolated from soil contaminated with poultry farm waste were determined on Skim milk Agar. 63 Bacillus strains were identified as proteolytic. Nine of these strains showed activity with the keratin-azure substrate and were determined to be keratinolytic. Amon...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111184


Mar 05, 2024Open    Access

Production and Process Optimization of an Emulsifier as a Tradition Food Salt (Nikki) from Musa paradisiaca (Plantain) Waste Peels Enriched with Ficus Waste Peels Ash and Evaluation of Its Effect on the Emulsification, Stabilisation and Sensory Properties of Yellow Achu-Soup

Kere Sinia Mboseh,Pride Ndasi Ngwasiri,Calister Wingang Makebe,Adanmengwi Vivian Akah,Ngwabie Martin Ngwa,Martin Benoit Ngassoum
Yellow achu-soup, an emulsion of red palm oil and water is a traditional delicacy in the grass field of Cameroon, which faces a problem of its stability due to the quality of the emulsifier used to emulsify and stabilize it. This study was designed for the optimization of the production of an emulsifier (Nikki) from Musa paradisiaca (Plantain) Peels enriched with Ficus Peels as a traditional food salt for the emulsification and stabilisation of yellow achu-soup. A fact...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111217


Mar 01, 2024Open    Access

Embryonic Development in Light of Controlled Chaos Dynamics and Quantum Electrodynami

Claudio Messori
Biological systems are necessarily dissipative structures in the long run, and dissipative structures are far from equilibrium and homeostasis: order (periodicity) and disorder (non-linear variability) are “coexisting dynamic states”. The common epistemological habit of modern molecular biology is to reduce an observed phenotype or function to a molecular entity, such as a gene, protein or pathway, which have become the embodiment of causation in biology. In the emerging framework of ge...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111264


Aug 18, 2023Open    Access

Biotechnological Drug Development—The Role of Proteins, Genes, In-Silico, and Stem Cells in Designing Models for Enhanced Drug Discovery

Taofik Ahmed Suleiman, Ann Christopher Francis, Abdulwasiu Ibrahim, Adedoyin Owolade Jonn-Joy, Ebenezer Adebiyi, Daniel Tweneboah Anyimadu
The application of biotechnology in drug discovery has been discovered to be a promising and resourceful approach for the discovery of novel therapeutic candidates that comes with less time and cost than the traditional ways of drug discovery. This has additionally endowed researchers with the necessary understanding of diseases, which offers exceptional methods for treating patients. Additionally, diagnosis and treatment are becoming increasingly intertwined with the help of biotechnology. Toda...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110520


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