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Jun 09, 2025Open    Access

Clinical Strategies for Managing Anticholinergic Toxicity in Overdose vs. Neuroleptic Malignant Syndrome: Diagnostic Challenges and Therapeutic Interventions

Rocco de Filippis,Abdullah Al Foysal
Neuroleptic Malignant Syndrome (NMS) and anticholinergic toxicity are two different but clinically similar disorders that are commonly seen in neuropsychiatric and emergency toxicological settings. Rapid differential diagnosis is made more difficult by the symptoms of both disorders, which frequently include delirium, heat, and autonomic instability. Interventions that result from misidentification may be detrimental or ineffectual. Using a machine learning-driven methodology, this work attempts...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1113510


Mar 25, 2025Open    Access

Verification of Quantitative Analytical Methods for Routine Clinical Biochemistry Analytes on Alinity ci Series and Architect ci 8200 at the Mohammed VI University Hospital of Oujda (Morocco)

Oussama Rahhab,Dounia El-Moujtahide,El-Houcine Sebbar,Mohammed Choukri
This study aimed to independently assess the analytical performance of 56 routine clinical biochemistry parameters on the ABBOTT Alinity ci Series and Architect ci 8200 automated systems, ensuring compliance with ISO 15189 standards. The verification followed Scope A criteria from the Medical Biology Method Verification/Validation Guide, focusing on repeatability and reproducibility. The coefficient of variation (CV) was compared to limits established by recognized learned societies such as the ...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1113040


Feb 17, 2025Open    Access

AI-Driven Pneumonia Diagnosis Using Deep Learning: A Comparative Analysis of CNN Models on Chest X-Ray Images

Abdullah Al Foysal,Sumaiya Sultana
Pneumonia remains a significant cause of morbidity and mortality worldwide, particularly in vulnerable populations such as children and the elderly. Early detection through chest X-ray analysis plays a crucial role in timely treatment; however, reliance on radiologists can lead to variability, delays, and diagnostic errors. This paper presents a convolutional neural network (CNN) designed to automate pneumonia diagnosis from chest X-ray images, addressing the need for faster and more consistent ...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112899


Jan 08, 2025Open    Access

Advancement in Nanoparticle-Based NIRF Probes for Precision Visualization in Oncology

Michael Adeniyi
Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, hold significant promise for in vivo visualization, due to their ability to access biological tissues and significantly reduce background interference from autofluorescence. Nanoparticles integrated with IR dyes have undergone extensive investigation regarding their pharmacokinetic behavior, including biodistribution patterns and clearance mechanisms. These nanoparticles exhibit a remarkable ability to prefere...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112471


Nov 08, 2024Open    Access

The Role of Artificial Intelligence in Diagnostic Medicine: A Narrative Review

Ali Abdin
Artificial intelligence (AI) has been with us since the 1950s and has long since undergone major developments in its capabilities and complexities, but it has recently evolved to a point where its capabilities have been substantially enhanced, all thanks to technological advances in the field of AI and modern hardware. While AI has already found applications in medicine, new revolutionary uses for it are emerging that could profoundly impact the future of healthcare for both clinicians and patie...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1112432


Jul 25, 2024Open    Access

Smartphone Oximeter SpO2 Integrated Measurement

Yahweh Van Ram Sri
Smartphone-based Oximetry device as early healthcare detection is a technological frontier. Smartphone oximetry devices offer a convenient method for remote SpO2 monitoring and early detection of critical health issues, especially during pandemics when vital indicators are necessary. Rising healthcare demands, and the COVID-19 pandemic are recent causes necessitating the prevalence for accessible early detection tools. This research investigates smartphone oximetry device as a conveni...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111580


Mar 01, 2024Open    Access

Correlation of High-Resolution Ultrasonography and Conventional Radiography in the Evaluation of Heel Pain at Kenyatta National Hospital

Suhaila Salim Abeid,Gladys Nthambi Mwango,Callen Kwamboka Onyambu
Background: The recent improvements in ultrasound technology coupled with wide availability, safety, portability, cost-effectiveness, non-ionizing with high spatial resolution renders it the initial choice of imaging for the evaluation of most musculoskeletal diseases. Ultrasound is a particularly useful tool to quickly and accurately localize and characterize pathologies of the sole. Heel pain is a common presenting complaint and affects a wide range of the adult population. Pl...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111174


Jan 24, 2024Open    Access

Comparison of Magnetic Resonance Imaging and Arthroscopy Findings in the Diagnosis of Meniscus and Anterior Cruciate Ligament Injuries

Branko Baljak, Jovana Baljak, Miodrag Vranjes, Milan Tosic, Tanja Lakic, Srdan Ninkovic
The knee joint injuries are one of the most common injuries of the human body. Since the medical examination is often insufficient to make a clinical diagnosis, we use additional diagnostic methods such as magnetic resonance imaging and arthroscopy. The aim of this work is to compare a magnetic resonance imaging and arthroscopic examination in meniscal and anterior cruciate ligament injury diagnosis. The study included 100 patients treated by knee arthroscopy with previously performed magnetic r...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111116


Nov 15, 2023Open    Access

Recurrent Thymoma with Lung, Pleural, and Splenic Metastases Demonstrated on F-18 FDG PET/CT

Deverly Tumapon, E. Edmund Kim
Thymomas are rare, slow-growing, and less aggressive anterior mediastinal tumors of epithelial origin. Its propensity for extra-thoracic spread is uncommon. Regional assessment by chest CT-scan has been the imaging modality of choice for disease staging and restaging. However, there are reported cases of hematogenous metastases to the brain, liver, pancreas, and kidneys but very rarely to the spleen. We reported a case of recurrent thymoma with metastases to the lung, pleura, and spleen. F-18 FD...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110817


Jul 21, 2023Open    Access

Atopic Dermatitis Related to RNF31 Genetic Variant

César Daniel Alonso-Bello, Sonia del Carmen Chávez-Ocana, Carol Vivian Moncayo-Coello, María Isabel Rojo-Gutierrez
Atopic dermatitis is a chronic and inflammatory skin disease and the most severe forms could strongly impact the patient’s quality of life. Skin barrier dysfunction is considered the first step in the atopic march. RNF31 deficiency significantly changes the skin structure and increases its thickness. The keratinocytes show decreased expression of K10 and loricrin. In this way, RNF31 deficiency alters the proper functioning of the skin by altering the homeostasis of keratinocytes. W...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110339


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