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Apr 28, 2023Open Access
Psychological mechanisms are often adopted by cancer patients to cope with the disease. This work aimed to describe the coping strategies adopted by cancer patients and to verify the psychometric properties of a Moroccan Arabic version of the Coping Strategies (AKU) questionnaire. A cross-sectional study was conducted on patients with breast and cervical cancer. Data collection was based on a questionnaire containing elements of the AKU’s adaptation strategies. Internal reliability was assessed ...
Apr 24, 2023Open Access
Obesity-induced hematologic changes in children in sub-Saharan Africa are poorly documented. The aim of this study is to determine obese adolescents’ hematological profiles and analyze the associations between some anthropometric and hematological parameters. A cross-sectional and comparative study was carried out in Brazzaville among adolescents attending school. A total of 82 adolescents (aged 11 - 17 years: mean age: 14.9 years), were enrolled in the study and were divided into 45 obese, 17 o...
Mar 14, 2023Open Access
The epithelioid angiomyolipoma (EAML) is a variant of angiomyolipoma with predominant epithelioid component which has a potentially malignant behavior. We report a 40-year-old woman with the synchronous renal and hepatic epithelioid angiomyolipoma with preoperative papillary thyroid carcinoma. She had been operated to remove the tumors in her liver and kidney. The histopathological and immunohistochemical results of surgical specimens were concordant with epithelioid angiomyolipoma. Her thyroid ...
Jan 18, 2023Open Access
Aneurysm of the vein of Galen is a pseudo-aneurysmal dilation of the ampulla of Galen with one or more arteriovenous fistulas, discovered ante or postnatally. We report two cases for which the diagnoses of aneurysm of the vein of Galen were made in the neonatal period at 5 and 17 days of life in front of clinical signs of heart failure and an intracranial murmur. Cardiac ultrasound remains a tool that can guide the diagnosis objectifying the ascending diastolic flow at the level of the arch of t...
Jan 17, 2023Open Access
Introduction: A combination of chemotherapy regimen and biologics in patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) resulted in improvements in survival. However, the optimal choice of initial biologic therapy in previously untreated patients remains challenging. Aim: The objective of this study is to compare the efficacy and safety outcomes of first-line epidermal growth factor receptor (EGFR) inhibitors versus vascular endothelial growth factor (VEGF) inhibitors in patien...
Dec 31, 2022Open Access
This study aims to compare 3DCRT & IMRT plans for two groups of prostate cancer patients i.e. “Prostate Only (PO) group” means the planning target volume includes the prostate & a margin of 1 cm from all sides except 0.6 cm from the posterior side & “Prostate Seminal Vesicles (PSV) group” means the PTV includes Prostate & Seminal Vesicles surrounded with a margin of 1 cm from all sides except 0.6 cm from the posterior side. Total of 17 patients has been studied. Among them, 9 patients belong t...
Dec 23, 2022Open Access
Autophagy is an important biological mechanism to transport proteins in organelles to lysosome for degradation, maintaining a stable physiological balance of the body. Acute Myeloid Leukemia (AML) refers to hematological malignancy caused by a disorder of myeloid hematopoietic stem cells. Recent studies have shown that the expression of some autophagy-related genes in AML patients is closely related to the prognosis and leukocyte formation of AML patients. Therefore, we can use autophagy as a po...
Oct 21, 2022Open Access
Breast cancer is the most common and deadliest cancer in women. The association of breast cancer and pregnancy is relatively rare and has a poor prognosis due to often late diagnosis and a high potential for lymphatic dissemination. It poses many diagnostic, therapeutic, prognostic and psychological problems. We report a case of ductal carcinoma of the breast associated with pregnancy in a 27-year-old patient. The diagnosis was late as well as the care which began 4 weeks after delivery. Obstetr...
Aug 19, 2022Open Access
Background: Salivary duct carcinoma (SDC) is one of the most aggressive malignant salivary gland tumors resembling high-grade mammary ductal carcinoma, with frequent local recurrence and regional lymph node and distant metastasis. SDC is often the absence of estrogen receptor and progesterone receptor, and Her2/neu overexpression. Treatment with molecular targeted therapy correlated well with long-term survival and therapeutic response in SDC patients. Purpose: We presented the clinicopathologic...
Jun 29, 2022Open Access
Neuroendocrine carcinoma (NEC) is a malignant tumor with a poor prognosis and can grow at many different sites in the body, but the colon is a very rare site. Clinical Case: We report a case of a 62-year-old man operated on for a tumor of the cecum, which was diagnosed as a high-grade neuroendocrine carcinoma. An immunohistochemical study showed positive marking with synaptophysin. No cancer metastasis was found. Postoperative chemotherapy was applied but the patient died after ...
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