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Archive of "Cell Death and Differentiation".

ISSN Print: 1350-9047

ISSN Online:

Website: https://www.ncbi.nlm.nih.gov/pmc/journals/1474/

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Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis

Alexander Poltorak,Amy Y. Tang,Anton Buzdin,Beiyun C. Liu,Chi G. Weindel,Hayley I. Muendlein,Irina Smirnova,Joseph Sarhan,Katherine A. Fitzgerald,Maxim Sorokin,Vladimir Ilyukha

Mutant p53 as a guardian of the cancer cell

Fiamma Mantovani,Giannino Del Sal,Licio Collavin

Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids

Eric Hoste,Tom Vanden Berghe

Necroptosis in anti-viral inflammation

Francis Ka-Ming Chan,Himani Nailwal

The UbL-UBA Ubiquilin4 protein functions as a tumor suppressor in gastric cancer by p53-dependent and p53-independent regulation of p21

Changzhi Huang,Dongdong Li,Hong Lin,Jia Wang,Lanfen Li,Mei Zhao,Min Liu,Qiao Zhang,Shengkai Huang,Weiyan Huang,Wenjie Wang,Xin Dong,Xinghua Yuan,Yan Li,You Li,Yuan Li

Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications

Francesca Nazio,Francesco Cecconi,Franco Locatelli,Matteo Bordi,Valentina Cianfanelli

Autophagy in endothelial cells and tumor angiogenesis

Diede Houbaert,Marco B. Schaaf,Odeta Me？e,Patrizia Agostinis

Nucleophagy: from homeostasis to disease

Margarita-Elena Papandreou,Nektarios Tavernarakis

lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation

Hongkun Liu,Hongwei Yang,Junwei Hao,Lijuan Zhang,Long Jia,Qi Zhang,Rongxin Zhang,Wen Li,Xiangdong Guo,Yan Li,Ying Liu,Yinghui Ren,Yurong Da,Zhenyi Xue,Zhi Yao,Zhihui Zhang,Zimu Zhang

The cisd gene family regulates physiological germline apoptosis through ced-13 and the canonical cell death pathway in Caenorhabditis elegans

Chipo F. Gray,Luhua Song,Pamela A. Padilla,Rachel Nechushtai,Ron Mittler,Skylar D. King,Tina L. Gumienny

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

Eef Parthoens,Hanne Van Gorp,Mohamed Lamkanfi,Nathalia M. de Vasconcelos,Nina Van Opdenbosch

MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration

Boreum Hwang,Eunju Lee,Inhwa Hwang,Je-Wook Yu,Junghyun Son,Sangjun Park,Sujeong Hong,Yoeseph Cho

Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity

Anne-Claire Compagnion,Annette Koulakoff,Chenju Yi,Christian Giaume,Etienne C. Hirsch,Frank W Pfrieger,Fran？ois Tronche,Layal Maatouk,Luc Leybaert,Maria-Angeles Carrillo-de Sauvage,Pascal Ezan,Sheela Vyas,Stéphane Hunot

Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

Changyin Yu,Chao Qu,Daxun Piao,Fengqin Lin,Juan Huang,Junfei Jin,Meihua Lin,Qiang Huang,Qin Wu,Tian Yu,Xiaolong Xie,Xiaoqi Xie,Xingfeng Qiu,Xuehui Hong,Yanwei Xing,Yanyan Jia,Yuanfu Lu,Yuekun Zhu,Yunmei Luo,Zhiyong Zhang

Death and fire—the concept of necroinflammation

Andreas Linkermann

Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2

Ann Janssens,Claudio Martines,Dimitar G. Efremov,Geert Bultynck,Giampaolo Morciano,Haidar Akl,Humbert De Smedt,Jan B. Parys,Kathia Dubron,Katja Rietdorf,Katsuhiko Mikoshiba,Kirsten Welkenhuyzen,Luca Laurenti,Mart Bittremieux,Martin D. Bootman,Myriam Baes,Paolo Pinton,Peter Vandenberghe,Rita M. La Rovere

Why do BCL-2 inhibitors work and where should we use them in the clinic?

Antony Letai,Joan Montero

Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM

Kurt Engeland

Mechanisms of transcriptional regulation by p53

Joaquin M Espinosa,Kelly D Sullivan,Matthew D Galbraith,Zdenek Andrysik

Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis

Deborah Chiabrando,Emanuela Tolosano,Federico Mussano,Fiorella Altruda,Francesca Vinchi,Giada Ingoglia,Giorgio Roberto Merlo,Lorenzo Silengo,Luca Munaron,Sara Petrillo,Stefano Carossa,Tullio Genova,Veronica Fiorito

Sumoylation of Notch1 represses its target gene expression during cell stress

Cecilia Sahlgren,Christian J. M. Antila,Henri A. Blomster,Johan Holmberg,K？the M. Dahlstr？m,Lea Sistonen,Tiina A. Salminen,Vilma Rraklli

Mammalian endoreplication emerges to reveal a potential developmental timer

Alberto Gandarillas,Natalia Sanz-Gómez,Rut Molinuevo

Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism

Alice Nemajerova,Gerry Melino,Ivano Amelio,Jakob Gebel,Ute M Moll,Volker D？tsch

Mutant p53 partners in crime

Guillermina Lozano,Michael P Kim

Necroptosis in microglia contributes to neuroinflammation and retinal degeneration through TLR4 activation

Bing Cheng,Chang He,Mei Li,Tian Zhou,Xialin Liu,Xiaowei Sun,Yingfeng Zheng,Zijing Huang

BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells

Lionel Rohner,Michaela Fux,Ramona Reinhart,Simone Wicki,Thomas Kaufmann

A miR-20a/MAPK1/c-Myc regulatory feedback loop regulates breast carcinogenesis and chemoresistance

Chang Bao,Chenggong Li,Chengyong Du,Danni Chen,Donghai Jiang,Jiaying Shen,Jie Pan,Junchi Cheng,Liang Xu,Minya Yao,Peifen Fu,Weimin Fan,Wengong Si,Xidong Gu

Resolution of inflammation and sepsis survival are improved by dietary Ω-3 fatty acids

Andreas K？rner,Hannes Frohnmeyer,Julia Theurer,Marieke Heijink,Martin Giera,Martin Schlegel,Michael Adolph,Peter Rosenberger,Valbona Mirakaj

The tango of ROS and p53 in tissue stem cells

Changshun Shao,Keli Liu,Youguo Chen,Yufang Shi

BOK promotes chemical-induced hepatocarcinogenesis in mice

Andreas Villunger,Daniel Bachmann,Deborah Stroka,Giulio Loforese,Matteo Montani,Simone Wicki,Tatiana Rabachini,Thomas Kaufmann,Valentina Sladky,Yuniel Fernandez-Marrero,Zhaoyue He

Diacylglycerol triggers Rim101 pathway–dependent necrosis in yeast: a model for lipotoxicity

Andreas Zimmermann,Campbell W. Gourlay,Didac Carmona-Gutierrez,Frank Madeo,Guido Kroemer,Ines Foessl,Joakim Franz,Julia Ring,Jutta Diessl,Martin Smolnig,Mina Bashir,Muhammad J. Khan,Oskar Knittelfelder,Patrick Rockenfeller,René Rost,Ronald P. Kühnlein,Sabrina Büttner,Sepp D. Kohlwein,Stephan J. Sigrist,Tobias Eisenberg,Vera Schmiedhofer,Wolfgang F. Graier

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Aaron Ciechanover,Abhishek D. Garg,Adi Kimchi,Alexey V. Antonov,Ana J. García-Sáez,Andreas Linkermann,Andreas Strasser,Andreas Villunger,Andrew Oberst,Andrew Thorburn,Antonella Sistigu,Atan Gross,Bertrand Joseph,Beth Levine,Boris Turk,Boris Zhivotovsky,Brent R. Stockwell,Brian D. Dynlacht,Carlos López-Otín,Carmen Garrido,Catherine Brenner,Cecilia M.P. Rodrigues,Christoph Borner,Claudio Hetz,Colin S. Duckett,Cristina Mu？oz-Pinedo,Daniel J. Klionsky,Daolin Tang,David C. Rubinsztein,David M. Pereira,David W. Andrews,David Wallach,Didac Carmona-Gutierrez,Dieter Adam,Domagoj Vucic,Douglas R. Green,Edward A. Miao,Eleonora Candi,Eli Arama,Emad S. Alnemri,Emily H. Cheng,Emre Sayan,Enrico Lugli,Eric H. Baehrecke,Erwin F. Wagner,Evripidis Gavathiotis,Eyal Gottlieb,Feng Shao,Francesca Bernassola,Francesco Cecconi,Francesco Di Virgilio,Francis K.-M. Chan,Frank Madeo,Gabriel A. Rabinovich,Gabriel Nu？ez,Gerald M. Cohen,Gerry Melino,Gian Maria Fimia,Guido Kroemer,Gwenola Manic,Gyorgy Hajnoczky,Gyorgy Szabadkai,Hamsa Puthalakath,Hans-Uwe Simon,Henning Walczak,Herbert W. Virgin,Hidenori Ichijo,Hinrich Gronemeyer,Ilio Vitale,Isaac S. Harris,Ivano Amelio,J. Marie Hardwick,James A. Wells,Jan Paul Medema,Jean-Christophe Marine,Jean-Claude Martinou,Jeffery D. Molkentin,Jerry E. Chipuk,Jochen H.M. Prehn,John A. Cidlowski,John J. Lemasters,John M. Abrams,John Silke,John W. Elrod,Josef M. Penninger,Juan R. Cubillos-Ruiz,Junying Yuan,Karen H. Vousden,Katiuscia Bianchi,Kevin M. Ryan,Klas Blomgren

Sex disparity in cancer: roles of microRNAs and related functional players

Alessandra Carè,Lucia Gabriele,Maria Bellenghi,Paola Matarrese,Stefano Salvioli,Walter Malorni

The BCL-2 arbiters of apoptosis and their growing role as cancer targets

Jerry M Adams,Suzanne Cory

BCL2: a 30-year tale of life, death and much more to come

Francesca Pentimalli

MOMP, cell suicide as a BCL-2 family business

Douglas R Green,Halime Kalkavan

Anti-apoptotic BCL-2 family members in development

Anisha Kothari,Joseph T Opferman

Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system

Chencheng Yao,Chong Li,Fan Zhou,Hong Wang,Hongyong Fu,Jingmei Hou,Liping Wen,Min Sun,Minghui Niu,Qingqing Yuan,Shaorong Gao,Wei-Qiang Gao,Zheng Chen,Zheng Li,Zuping He

Basal p53 expression is indispensable for mesenchymal stem cell integrity

Christopher L. Haga,Cori N. Booker,Donald G. Phinney,Jacqueline Strivelli,Siddaraju V. Boregowda,Veena Krishnappa

Anti-apoptotic A1 is not essential for lymphoma development in Eμ-Myc mice but helps sustain transplanted Eμ-Myc tumour cells

Cassandra J. Vandenberg,Marco J. Herold,Mark Mensink,Mikara Robati,Natasha S. Anstee,Robyn L. Schenk,Suzanne Cory

APP upregulation contributes to retinal ganglion cell degeneration via JNK3

Chao Liu,Cheng-Wu Zhang,Edward H. Koo,Gavin S. Dawe,Kah-Leong Lim,Lawrence W. Stanton,Liying Corinne Lee,Sung Ok Yoon,Tuck Wah Soong,Wan Qing Wong,Wanjin Hong,Wei Yi Ong,Xin-Yuan Fu,Yi Zhou,Zhi-Cheng Xiao

Turning an old GADDget into a troublemaker

Daniel D’Andrea,Daniela Verzella,Daria Capece,Federica Begalli,Francesca Zazzeroni,Guido Franzoso,Jason Bennett,Laura Tornatore

RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain

Jianwei Jiao,Qingli Liang,Wei Li,Wenlong Xia

Coordinated repression of BIM and PUMA by Epstein–Barr virus latent genes maintains the survival of Burkitt lymphoma cells

Andreas Strasser,Andrew I Bell,Andrew J Boyce,Catherine Chang,Deborah Croom-Carter,Gemma L Kelly,Leah Fitzsimmons,Marco J Herold,Martin Rowe,Rosemary J Tierney,Wenbin Wei

SIRT3/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress

Jiangang Long,Jiankang Liu,Jie Xu,Jing Gao,Jing Liu,Ke Cao,Lei Chen,Mengqi Zeng,Shujun Han,Weili Shen,Xueqiang Wang,Zhihui Feng,Zongfang Li

BCL-2 family proteins: changing partners in the dance towards death

David W Andrews,Elizabeth J Osterlund,Justin Kale

Updates from the TP53 universe

Francesca Pentimalli

A large shRNA library approach identifies lncRNA Ntep as an essential regulator of cell proliferation

Christian B？r,Dominique Kirste,Dongchao Lu,Felix Kleemi？,Julia Beermann,Katharina Iwanov,Katharina Schimmel,Regalla Kumarswamy,Thomas Thum

Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice

Carla Brancia,Cristian Antonio Caria,Ester Musu,Isadora Asunis,Lucia Perseu,Maria Francesca Manchinu,Maria Serafina Ristaldi,Michela Simbula,Susanna Porcu

The Bcl2a1 gene cluster finally knocked out: first clues to understanding the enigmatic role of the Bcl-2 protein A1

David A Hildeman,Ingolf Berberich

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