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Jan 08, 2025Open Access
Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, hold significant promise for in vivo visualization, due to their ability to access biological tissues and significantly reduce background interference from autofluorescence. Nanoparticles integrated with IR dyes have undergone extensive investigation regarding their pharmacokinetic behavior, including biodistribution patterns and clearance mechanisms. These nanoparticles exhibit a remarkable ability to prefere...
Dec 11, 2024Open Access
Introduction: The increased use of antibiotics in livestock production, particularly poultry, has prompted serious public health concerns due to the possibility of antibiotic residues in the food supply chain. This study examined the levels of tetracycline residues in broiler chicken meat samples including liver, small intestine, and thigh muscle tissues collected from two major markets in Zanzibar namely, Mwanakwerekwe and Darajani. An enzyme-linked immunosorbent assay test was...
Apr 30, 2024Open Access
Guillain-Barré syndrome (GBS) is an immune-mediated polyradiculoneuropathy. It is recognized as a serious condition, because it includes dysautonomia and respiratory affection. In fact, there have been an increasing number of reports about GBS vaccine-related vaccinations as the COVID-19 vaccination campaign goes on. Here, we report two cases of Guillain-Barré syndrome (GBS) following the first dose of the Oxford/AstraZeneca COVID-19 vaccine. Symptoms appeared 21 days after vaccination, with acu...
Mar 26, 2024Open Access
In medical practice, X-ray is mainly used as a diagnostic test and a type of radiation therapy for cancer and other diseases. However, the X-rays seem no use in the prevention of diseases. Since X-rays can alter gene expression patterns in host cells, it might have capacity to protect people from all viral infections based on our antiviral theory. We assume that X-ray irradiation on the upper respiratory tract could protect normal people from respiratory viral infections. If a low-dose X-ray irr...
Dec 08, 2023Open Access
Drug resistance in pathogens including cancer cells, bacteria, protozoa, fungi and viruses remains the major global health challenge. To deal with drug resistance in pathogens, an understanding of drug resistance development is of great importance. Recently, we published a hypothesis that drug resistance in malaria parasites could be determined by the altered 3D genome architecture which regulates many normal genes in malaria parasites to form a “specific antidrug group of protein combinations” ...
Nov 10, 2023Open Access
The occurrence of acute hemolysis in a patient with stable hemoglobinosis can be of corpuscular or extra-corpuscular origin. We report the case of a patient with sickle cell disease SS stable for twenty years, who is treated with levofloxacin for sepsis with a urinary starting point. Biology: hyperleukocytosis at 33,570/mm3 made up of 90% neutrophils and CRP at 160 mg/l, hemolytic, mechanical, nonthrombocytic microcytic anemia (Hb at 8.3 g/dl, VGM at 70 μm3, haptoglobulin collapsed ...
Aug 30, 2023Open Access
The formula for the natural frequency of torsional vibrations of the DNA helix is obtained by methods of mathematical physics. The data on the dependence of E. coli survival on the time of exposure to centimeter waves were analyzed, the numerical coefficient in the resulting formula was determined. According to this formula, the resonant frequency for the DNA of another strain of E. coli was found. When irradiated with centimeter waves of this frequency, a significant decrease in t...
Aug 28, 2023Open Access
Background: An accurate assessment of the spasticity in the spastic forms of cerebral palsy (CP) is important to establish the effectiveness of therapeutic management. The modified Ashworth scale (MAS) is the most frequently used method in the assessment of spasticity in clinical practice. However, this method does not allow an objective, precise and reliable assessment because of the lack of standardization and the low level of reliability. Elastosonography (ES) is an imaging method that assess...
Jul 31, 2023Open Access
In dentistry, herbal medicine naturally falls within the professional capacity of stomatologists or dental surgeons and can be particularly useful. The use of medicinal plants, for preventive, therapeutic purposes or for oral hygiene, falls within the professional capacity of doctors-stomatologists and dental surgeons. But they have to be competent in the matter, especially since no plant is harmless. After regulatory information, for documentary purposes, some examples of use are reported and, ...
Jun 13, 2023Open Access
The article theoretically and experimentally substantiates a new method in the free-radical theory of aging, where the target is not the free radicals but the DNA molecules; while radioprotectors are used as antioxidants, previously used to protect the body from radiation damage. A brief overview of various strategies and methods in gerontology is provided. In the quasicrystalline model of DNA, the role of impurity levels is considered. The electronic spectra of DNA bases were calculated by the ...
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