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Oct 18, 2024Open    Access

Two-Sample Mendelian Randomization Analysis of the Causal Relationship between Intestinal Flora and Childhood Obesity

Dewei Xu,Hong Wang
Objective: To evaluate the potential causal relationship between 182 gut microbiota and childhood obesity by two-sample Mendelian randomization. Methods: The data source was the summary data of genome-wide association study (GWAS), and 182 intestinal microbiota contained 874 single nucleotide diversity (SNPs). The childhood obesity data contained 2,442,739 SNPs. Mendelian randomization analysis was performed using three methods: inverse variance weighting (IVW), weighted median,...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1112342


Jun 28, 2024Open    Access

Comparative Study of Microbiological and Molecular Diagnosis (Bac Multi-Screen-Real-TMkit) of Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus pneumoniae, and Streptococcus spp. Strains from Urinary and Vaginal Secretions in Ouagadougou (Burkina Faso)

Bagora Bayala,Léa Nikiema,Prosper Bado,Salif Sombié,Marc Donald Wilfried Adico,Arouna Soré,Jacques Simporé
Introduction: The last few decades have seen considerable progress in the diagnosis and medical management of infectious diseases. Among these diseases, urogenital infections caused by Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus pneumoniae and Streptococcus spp. remain a major cause of morbidity and mortality in Ouagadougou (Burkina Faso). The aim of this study was to evaluate the performance of the Bac Multi-Screen-Real-TMkit com...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111569


May 10, 2024Open    Access

Prevalence, Antimicrobial Susceptibility Profile of Citrobacter and Risk Factors Associated with Diarrheal Diseases in Water Wells in Urban West Region, Zanzibar

Gharibu A. Ibrahim,Alexanda Mzula,Isaac Makundi,Elisa Mwega
Citrobacter are Gram-negative bacteria that give public health challenges due to their zoonotic infections. Diarrheal diseases and antimicrobial resistance are global concerns that increase the burden of implementing infectious disease monitoring, especially in poor economic countries. This study was conducted to determine the prevalence and antimicrobial susceptibility and assess the risk factors of diarrheal diseases caused by bacteria from drinking water wells in the Urban West Regio...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111232


Oct 26, 2023Open    Access

One-Way Analysis and Correlation Analysis of Design Parameter’s Influence on the Work Condition of Vermifilter

Fatima Hamed, Meiyan Xing
Vermifilter, based on earthworm-microorganism synergistic action, could simultaneously achieve the reduction and stabilization of excess sludge environment-friendly. To make vermifilter work more efficiently and steadily, the diameter of ceramsite, filter height, and influent concentration were investigated in this study. The results showed that though larger ceramicite may decrease the rate of suspended solids (SS) reduction and volatile suspended solids (VSS) reduction slightly, it can improve...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110771


Sep 01, 2023Open    Access

Osteopetrosis Case Series from Tanzania

Lee Kapalisya Mwakalinga, Rogers Joachim Temu, Honest Massawe, Mathias Ncheye, Zawadi Mahumbuga, Octavian Allexander Shirima, Mubashir Jusabani, Regnald Shoo, Anthony Japhet Pallangyo
Osteopetrosis is a rare group of sclerosing bone dysplasia characterized by diminished skeletal resorption. Typical osteopetrosis has the hallmark symptom of increased bone mass with related symptoms resulting from increased bone density. The mainstay of diagnosis is clinical and largely depends on the radiographic appearance of the skeleton. In our case series, three adults were studied, presented with history of recurrent fractures on the extremities sustained after low energy injuries, histor...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110052


Aug 23, 2023Open    Access

Detection of blaVIM Gene in β-Lactam Resistant E. coli Isolated from Clinical Samples in Ouagadougou, Burkina Faso

Abdoul Karim Ouattara, Blandine Ouédraogo, Rahimatou Yasmine Wendkuni Tiemtoré, Amana Mètuor Dabiré, Serge Sougué, Jacques Simporé
Escherichia coli, a Gram-negative bacterium, is commonly associated community and hospital-acquired infections, with significant antibiotic resistance implications for public health. This study aimed to detect the blaVIM gene in E. coli strains isolated from the Centre Hospitalier Universitaire Pédiatrique Charles De Gaulle (CHUP-CDG) in Ouagadougou, Burkina Faso. E. coli strains were isolated from various biological samples (urine, pus, blood, stool, and c...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110534


Apr 20, 2023Open    Access

Melioidosis a Rare Cause of Infective Endocarditis: A Case Report

Chun Kiat Ng, Anuradha P. Radhakrishnan
Burkholderia pseudomallei is an unusual causative organism of infective endocarditis. We present a case of Melioidosis mitral valve endocarditis with dissemination to the liver and kidney in a young woman with underlying SLE with lupus nephritis. Despite the delay in reaching a diagnosis, the patient was successfully treated with intravenous Ceftazidime and oral trimethoprim-sulfamethoxazole and was discharged well. The identification of the specific aetiologic organism is important for t...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110004


Aug 22, 2022Open    Access

The Ancestors of Cryptococci Appeared on Earth 600 Million Years Ago

Petr Nikolayevich Kolosov
The purpose of the research is to study the early forms of life in the Neoproterozoic. To achieve this goal, the author has conducted the search for microfossils in stromatolites and has systematically identified the detected forms. In Eastern Siberia, 600-million-year-old Neoproterozoic rocks host columnar stromatolites. They were formed in the sublittoral areas of the warm sea and consisted almost entirely of mineralized (silicified) remains of yeast fungi that, during their life cycle, parasi...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109125


Jul 14, 2022Open    Access

Antibiotic Resistance and Phynotypic Detection of AmpC Beta-Lactamase Producing Escherichia coli from Urine of Students Attending Fulafia Clinic

Usman S. Okposhi, Kabiru A. Shuaibu, Chuku Aleruchi, Fatima A. Yusuf, Naja’atu S. Hadi
Escherichia coli also known as E. coli are gram-negative facultative anaerobic, rod-shaped, Coliform bacteria, commonly found in the lower intestine of warm-blooded organisms. This study was designed to determine the antibiotic susceptibility and the phenotypic detection of AmpC beta-lactamase producing Escherichia coli from the urine of students attending FuLafia Clinic, Nasarawa State, Nigeria. A total of 22 urine samples were collected from the students. Eleven (50%) E...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108550


Jun 10, 2022Open    Access

Taxonomy and Characterization of Fungi Isolated from Cocoa Beans during Fermentation in Saf’s Agroforestry System in the Amazon

Mateus Cardoso Barros, Jeferson Santana Quadros, Magnun Antonio Penariol da Silva, Raquel Soares Casaes Nunes
Agroforestry systems (SAFs) are an alternative for sustainable development as they enable the recovery of degraded areas and reduce deforestation, contributing to breaking the cycle of traditional family farming, so common in the Amazon region, which enables the recovery of soils, the increase of organic matter and soil fertility. Cocoa beans are grown and fermented in SAFs. According to the research, the significant appearance of endophytic microorganisms such as fungi in the cocoa bean can ben...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108825


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