Antivral and antiparasitic activities of various substituted triazole derivatives: A mini review

The presence of three nitrogen hetero-atoms in five-membered ring systems defines an interesting class of compounds, the triazole. This may be of two types, the 1,2,3-triazoles and the 1,2,4-triazoles. Out of the two triazoles, 1,2,4-triazole have drawn great attention due to its wide variety of activities, low toxicities and good pharmacokinetic and pharmacodynamic profiles. Chemistry of triazoles and their fused heterocyclic derivatives has received considerable attention owing to their effective biological activities such as anti inflammatory, analeptic, sedatives, antianxiety, antimicrobial, antimycotic and other pharmacological and chemical properties. In this article, antiviral and antiparasitic activities of triazole derivatives are discussed.