In this study we used a chemical solution method from oxalic acid (OX. acid)
and zinc acetate (ZnAc) to prepare Zinc Oxide nanoparticles (ZnONPs) and Zinc
Oxide nanoparticles doped with Chlorine (Cl:ZnONPs). The characterizations
(FTIR, X-ray, SEM, TEM) of ZnONPs and Cl:ZnONPs were determined. Amylase
inhibitors of ZnONPs and Cl:ZnONPs also were determined. SEM indicated that the
ZnONPs and Cl:ZnONPs have an average particle size of 46.65 - 74.64 nm. TEM
images of the ZnONPs and Cl:ZnONPs showed the round shaped. Compounds b,d and e
exhibited significant inhibitory activity against amylase enzyme(from
69.21±1.44 to 76.32±0.78), respectively, and were comparable with that of acarbose (86.32 ±
0.63) at 1000μg, thereby, projecting ZnONPs and Cl:ZnONPs as α-amylase inhibitors.
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