%0 Journal Article
%T Synthesis and Characterization of Zinc Oxide and Zinc Oxide Doped with Chlorine Nanoparticles as Novel <i>¦Á</i>-Amylase Inhibitors
%A A. Al-Arfaj Ahlam
%A N. Abd El-Rahman Soheir
%J Food and Nutrition Sciences
%P 308-318
%@ 2157-9458
%D 2021
%I Scientific Research Publishing
%R 10.4236/fns.2021.123024
%X In this study we used a chemical solution method from oxalic acid (OX. acid)
and zinc acetate (ZnAc) to prepare Zinc Oxide nanoparticles (ZnONPs) and Zinc
Oxide nanoparticles doped with Chlorine (Cl:ZnONPs). The characterizations
(FTIR, X-ray, SEM, TEM) of ZnONPs and Cl:ZnONPs were determined. Amylase
inhibitors of ZnONPs and Cl:ZnONPs also were determined. SEM indicated that the
ZnONPs and Cl:ZnONPs have an average particle size of 46.65 - 74.64 nm. TEM
images of the ZnONPs and Cl:ZnONPs showed the round shaped. Compounds b, d and e
exhibited significant inhibitory activity against amylase enzyme (from
69.21 ¡À 1.44 to 76.32 ¡À 0.78), respectively, and were comparable with that of acarbose (86.32 ¡À
0.63) at 1000 ¦Ìg, thereby, projecting ZnONPs and Cl:ZnONPs as ¦Á-amylase inhibitors.
%K Zinc Oxide Nanoparticles
%K Zinc Oxide Nanoparticles Doped with Chlorine
%K Crystallinity
%K Anti-Diabetic Activity
%K ¦Á-Amylase Inhibitors
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=108047