%0 Journal Article %T Synthesis and Characterization of Zinc Oxide and Zinc Oxide Doped with Chlorine Nanoparticles as Novel <i>¦Á</i>-Amylase Inhibitors %A A. Al-Arfaj Ahlam %A N. Abd El-Rahman Soheir %J Food and Nutrition Sciences %P 308-318 %@ 2157-9458 %D 2021 %I Scientific Research Publishing %R 10.4236/fns.2021.123024 %X In this study we used a chemical solution method from oxalic acid (OX. acid) and zinc acetate (ZnAc) to prepare Zinc Oxide nanoparticles (ZnONPs) and Zinc Oxide nanoparticles doped with Chlorine (Cl:ZnONPs). The characterizations (FTIR, X-ray, SEM, TEM) of ZnONPs and Cl:ZnONPs were determined. Amylase inhibitors of ZnONPs and Cl:ZnONPs also were determined. SEM indicated that the ZnONPs and Cl:ZnONPs have an average particle size of 46.65 - 74.64 nm. TEM images of the ZnONPs and Cl:ZnONPs showed the round shaped. Compounds b, d and e exhibited significant inhibitory activity against amylase enzyme (from 69.21 ¡À 1.44 to 76.32 ¡À 0.78), respectively, and were comparable with that of acarbose (86.32 ¡À 0.63) at 1000 ¦Ìg, thereby, projecting ZnONPs and Cl:ZnONPs as ¦Á-amylase inhibitors. %K Zinc Oxide Nanoparticles %K Zinc Oxide Nanoparticles Doped with Chlorine %K Crystallinity %K Anti-Diabetic Activity %K ¦Á-Amylase Inhibitors %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=108047