OALib Journal
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Jun 17, 2022Open    AccessArticle

Somite and Brain Nociceptive Coupling in Evolution of Nociceptive-Sympathetic Coupling for Pain Sensations by NBA

Zi-Jian Cai
In May 2016, it was proposed by the US athletes of the National Basketball Association (NBA) on television that the nociceptive-sympathetic coupling be required for pain sensations. Later, it was demonstrated that, via the activation of sympathetic outputs directly by the nociceptive neurons in laminae I and V of the dorsal spinal horn as well as those in periaqueductal grey (PAG) of brain, it was completed the nociceptive-sympathetic coupling in vertebrates. In this article, for the evolutionar...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108867


Sep 17, 2019Open    AccessArticle

Influencing Relaxation by a Low Intensity Transcranial Pulsed Magnetic Stimulation Applying the Entrainment Model

Igor Jerman, Primoz Dovc, Petra Ratajc
Relaxation is becoming increasingly important in modern stressful times. Besides special psychological practices or consuming pharmaceuticals, one can achieve a more relaxed state also by applying an appropriate magnetic field stimulation of the head (low-intensity rTMS). Following the entrain-ment model, we did the research using carefully chosen frequencies of modest MF intensity that followed the principles of clinical trials.
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Open Access Library J.   Vol.6, 2019
Doi:10.4236/oalib.1105741


Mar 15, 2018Open    AccessArticle

Detection of Horizontal Transfer of Housekeeping and Hydrocarbons Catabolism Genes in Bacterial Genus with Potential to Application in Bioremediation Process

Edmo Montes Rodrigues, Fernanda de Souza Freitas, Tatiane de Paula Siqueira
In silico analysis can be useful to infer about the horizontal gene transfer (HGT) as well as to deduce about the evolutionary relations of catabolic genes. In this study, we performed the analysis of two housekeeping genes (fabD and rpoD) and two catabolic gene
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Open Access Library J.   Vol.5, 2018
Doi:10.4236/oalib.1104454


Jan 23, 2017Open    AccessArticle

What Nanobacteria and Nanovesicles May Tell Us about the Origin of Life?

Igor Jerman
In contemporary, established biology life is almost exclusively treated as a molecular phenomenon. Therefore, the mystery of the origin of life is sought in molecular terms and processes. But according to certain advanced researches and considerations, life has also other essential “ingredients”: active and diffused organized information and a specific physical as well as physicochemical state of matter characterized
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Open Access Library J.   Vol.4, 2017
Doi:10.4236/oalib.1103348


Feb 03, 2016Open    AccessArticle

Regulation of Both Cell State and Gene Expression with Nutrient Gradient as Conserved Mechanism Differentiating the Cell Fates for Embryonic Gastrulation: A Theory

Zi-Jian Cai
In this article, it is newly suggested the regulation from nutrient gradient on both cell metabolic state and expressional gene classes as the conserved mechanism differentiating the cell fates for formation of the three germ layers of gastrula in animals. As a new theory, it is supported by the totipotency and pluripotency of early embryonic cells and cultured stem cells to be regulated by nutrients, as well as by the universal formation of nutrient gradient during gastrulation in various anima...
Open Access Library J.   Vol.3, 2016
Doi:10.4236/oalib.1102348


Jun 25, 2015Open    AccessArticle

Termination of Organogenesis as Intrinsic Constraint on Animal Development and Evolution: A Theory

Zi-Jian Cai
In this article, it is pointed out with integrative analysis that organogenesis manifests limitation in time and possession of termination, while infinite cell proliferation called as cancer and tumor is lethal. Besides, it is reversely demonstrated from a few notable constant outgrowing skin derivatives that termination is required for organogenesis inside the animal. Accordingly, it is suggested that the requirement for organogenetic termination would be the new intrinsic constraint for animal...
Open Access Library J.   Vol.2, 2015
Doi:10.4236/oalib.1101646


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