Sep 01, 2020Open AccessArticle
An important feature of blockchain technology is that all participants jointly maintain transaction data and can achieve mutual trust relationships without integrated control, which relies on distributed consensus algorithms. Practical Byzantine Fault Tolerant algorithm (PBFT) is a fault-tolerant algorithm based on state machine replication, which solves the Byzantine error, that is, the malicious behavior of nodes. In PBFT, all participating nodes are divided into the primary node and backup no...
Jun 24, 2020Open AccessArticle
Human cancer, which has complex pathogenesis, is generally relative to the dysfunction of biological systems. Thus, our research is not at molecular level, but at system level, i.e. molecular network. In this paper, specially, we use PPI network. In order to construct a PPI network, we used the SSN method which is proposed by Professor X. Liu and others. The SSN method is distinct from the traditional network methods, especially in screening differential expressed genes. Besides, the traditional...
Mar 15, 2018Open AccessArticle
In silico analysis can be useful to infer about the
horizontal gene transfer (HGT) as well as to deduce about the evolutionary
relations of catabolic genes. In this study, we performed the analysis of two
housekeeping genes (fabD and rpoD) and two catabolic gene
Mar 12, 2018Open AccessArticle
The imbalance between oxidant molecules and
antioxidant agents is characterized as oxidative stress (OS) and may lead to
severe damage to the organism. In contrast, the physical training of aerobic
and resistive character promotes increases of the antioxidant response,
resulting in a balance and/or minimizing damage. Therefore, the objective of
the study is to verify the effect of aerobic training, resistive training and
Jul 29, 2016Open AccessArticle
Genetic epidemiological studies have suggested that several genetic
variants increase the risk for hypertension.
It is likely that a number of genes rather than a single gene account for
the heritability of this complex disorder. However, the genetic analysis of
hypertension produced complex, inconsistent
and nonreproducible results, which makes it difficult to draw conclusions
about the association between specific genes
Mar 30, 2016Open AccessArticle
Motif discovery is one of the fundamental problems that have important applications
in identifying drug targets and regulatory sites. Regulatory sites on DNA
sequence normally correspond to shared conservative sequence patterns among the
regulatory regions of correlated genes. These conserved sequence patterns are
called motifs. Identifying motifs and corresponding instances is very
important, so biologists can investigate the interactions between DNA and
proteins, gene regulation, cell developm...
Sep 24, 2014Open AccessArticle
The Wisconsin Breast Cancer Dataset has been heavily cited as a benchmark dataset for classification. Neural Network techniques such as Neural Networks, Probabilistic Neural Networks, and Regression Neural Networks have been shown to perform very well on this dataset. However, despite its obvious practical importance and implications for cancer research, a thorough investigation of all modern classification techniques on this dataset remains to be done. In this paper we examine the efficacy of c...
Jun 05, 2014Open AccessArticle
In this study, the chromosome karyotype of Plumbago auriculata was analyzed by using a chro-mosome mounting technique with the primary root tip of seed germination. The aim was to find out the most suitable method for Plumbago auriculata by comparing the effect of different pretreatment and dissociation time on chromosome. The results showed that the best pretreatment was 0.05% colchicine solution under 0℃ - 4℃ or 2 h and then 1 mol/L HCL under 60℃ water for 6 min. Karyotype analysis of Plumbago...