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Jun 20, 2025Open Access
Background: Diabetes is one of the most widespread metabolic diseases worldwide and is responsible for approximately 4 million deaths per year in 2010. The global prevalence among adults was estimated at 4.6% affecting around 285 million people. This number rose to 371 million in 2012 and is projected to reach 552 million by 2030. Among the various factors that may influence the incidence of diabetes, infection with Helicobacter pylori has been increasingly studied for ...
Jun 03, 2025Open Access
Introduction: Paracetamol is the most common analgesic and antipyretic that is used in the hospital setting and as over the counter medication and is commonly preferred in pediatric patients. In pediatric population, the dosage error accounts for most cases of acetaminophen toxicity. Paracetamol poisoning may be as a single acute ingestion or as a result of the repeated use. Symptoms vary depending on the stage the patient is in. Serum ALT is routinely used in the diagnosis of hepatic injury fol...
May 27, 2025Open Access
Background: Despite the widespread use of lung ultrasound in clinical practice, there are no clear evidence-based guidelines for teaching lung ultrasound in the Democratic Republic of Congo (DRC). The aim of this study was to identify factors associated with the use of lung ultrasound by physicians in the DRC. Methods: Cross-sectional study, carried out online among 363 physicians in the DRC during the period from September to December 2024. Sociodemographic cha...
Mar 25, 2025Open Access
Background: Malaria is the leading cause of hospital admission in Africa and constitutes the greatest disease burden in the region. More than one hundred nations are affected worldwide with children and pregnant women being mostly vulnerable. Children under the age of five years suffer severe forms. Malaria is said to be severe when the acute illness is associated with a life-threatening event(s). Several organ systems including the kidney can be involved. In most cases, s...
Feb 24, 2025Open Access
Introduction: Pneumoperitoneum is a radiologic term denoting an abnormal collection of air in the peritoneal cavity. It reflects visceral perforation. Pneumoperitoneum without visceral perforation evidence after laparotomy is called spontaneous or idiopathic pneumoperitoneum. Case Report: We report a case of massive idiopathic pneumoperitoneum in a 3-day-old newborn. Unprepared abdominal x-ray revealed a massive pneumoperitoneum huge oval radiolucency delineated...
Oct 18, 2024Open Access
Objective: To evaluate the potential causal relationship between 182 gut microbiota and childhood obesity by two-sample Mendelian randomization. Methods: The data source was the summary data of genome-wide association study (GWAS), and 182 intestinal microbiota contained 874 single nucleotide diversity (SNPs). The childhood obesity data contained 2,442,739 SNPs. Mendelian randomization analysis was performed using three methods: inverse variance weighting (IVW), weighted median,...
Oct 17, 2024Open Access
Research Background: Birth asphyxia is a significant contributor to the overall neonatal mortality in Ghana and across the world, as it accounts for 900,000 deaths each year globally and 28% of the neonatal deaths in Ghana. Research Objectives: To determine the incidence of birth asphyxia, the maternal and neonatal associated factors, the outcome of birth asphyxia and duration of hospital stay of asphyxiated babies at St. Patrick’s Hospital, Of-finso, Ghana. ...
Sep 25, 2024Open Access
Introduction: Sickle cell anaemia, the most widespread genetic disease in the world, is an autosomal recessive hereditary disease characterised by the substitution of glutamic acid for valine in position 06 of the globin beta chain, giving rise to this aberrant haemoglobin S. The aim of this study is to determine the characteristics of patients with sickle cell anaemia admitted to the paediatric unit of Bogodogo University Hospital in Ouagadougou, Burkina Faso. Methods:...
Aug 22, 2024Open Access
A fifteen-year-old boy presented with a complex of clinical symptoms and signs of severe malaria; fever, convulsions, loss of consciousness, severe anaemia, hypoglycaemia and that of generalised tetanus; trismus, rigidity, reflex spasticity, tiny necrotic area on the plantar surface of the foot. The patient responded very poorly to intravenous artesunate, and blood transfusion among other measures for the management of severe malaria. A history of tetanus immunization could not be established. T...
Jul 03, 2024Open Access
Severe malaria is a major cause of mortality among children when not di-agnosed and treated at an early stage. It is classified as a medical emergency. In this study, the urinalysis was done using the dipstick method on 82 (50%) children with severe malaria and another 82 (50%) without severe malaria, serving as controls. Data collated during the study were analyzed using chi-square and p-value with the aid of SPSS 23 software. The study shows that the urine pH and specific gravity were normal i...
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