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Aug 05, 2026Open Access
Introduction: The objectives of this study were to determine the prevalence of heart failure among patients with chronic kidney disease, to describe their sociodemographic, clinical, and echocardiographic characteristics, and to identify prognostic factors associated with heart failure in the context of chronic kidney disease. Methodology: We conducted a prospective, descriptive cross-sectional study from May 1 to October 31, 2024. We included all patients aged 18 yea...
Mar 20, 2026Open Access
Lithium remains the most effective long-term treatment for bipolar disorder, yet its therapeutic benefits are offset by a well-established risk of chronic kidney disease (CKD). Anticipating lithium-associated renal impairment is clinically challenging because the underlying mechanisms are subtle, multi-variate, and evolve dynamically with cumulative exposure. In this study, we develop a transparent, end-to-end machine-learning framework for early detection of lithium-induced kidney damage using ...
Mar 20, 2026Open Access
Long-term lithium therapy remains the most effective maintenance treatment for bipolar disorder, yet it poses a significant risk of progressive renal impairment in a subset of patients. Early recognition of individuals vulnerable to lithium-associated nephrotoxicity is clinically critical but challenging, given the heterogeneous evolution of renal biomarkers, nonlinear exposure effects, and complex interactions with comorbidities and concomitant medications. In this work, we introduce a multimod...
Nov 19, 2025Open Access
Background and Aim: Chronic Kidney Disease is a serious public health concern globally; however, it hits hard in resources constraint countries where health infrastructure is inadequate. Ghana’s prevalence is 13.3%, amidst poor access to life-saving interventions such as hemodialysis. Yet, less is known about the experiences of people seeking haemodialysis therapy in Northern Ghana. The authors sought to explore the experiences of people seeking hemodialysis therapy at a tertiary hospital in Gha...
Aug 12, 2025Open Access
Objective: To describe the clinical manifestations, anatomopathology and therapeutic management of patients. Methodology: This was a retrospective prospective descriptive and analytical study of ten (10) patients followed from November 2017 to September 2024 in the nephrology department of the Centre Hospitalier South Francilien for GNEC. All patients who underwent renal puncture-biopsy with confirmation of extracapillary glomerulonephritis (ECG) were included. Results: During the course of our ...
Aug 12, 2025Open Access
Introduction: Heart failure (HF) is a significant public health issue. The objective of this study was to investigate acute kidney injury in the cardiology department. Material and Methods: We conducted a cohort study in the cardiology department over a period of 6 months, from January 1 to June 30, 2024. We included all patients hospitalized for decompensated heart failure (HF) whose diagnosis of acute kidney injury (AKI) was confirmed by a sudden increase in creatinine associated with a urinar...
Jul 23, 2025Open Access
Introduction: The aim was to determine the prevalence of types of hypertension during pregnancy and to describe the sociodemographic and clinical characteristics of patients with hypertension during pregnancy in Conakry. Methodology: This was a prospective cross-sectional descriptive study lasting 6 months, from July 1 to December 31, 2022. carried out in the obstetrics and gynecology department of the Ignace Deen University Hospital. We included all women with ...
Jun 13, 2025Open Access
Introduction: The objective of this observational study on a local cohort was to report the prognostic interest of using a High Cut-Off membrane dialysis protocol in the management of MM (myeloma tubulopathy) in patients with severe dialysis-dependent acute kidney injury (AKI). Methodology: This was a retrospective study conducted over a one-year period from September 1, 2023, to August 31, 2024. All hospitalized patients with dialysis-dependent AKI diagnosed with MM were treated according to th...
Apr 11, 2025Open Access
Background and objectives: Lupus nephritis is one of the most common complications of Systemic Lupus Erythematosus, due to the accumulation of immunocomplexes of antigens and antibodies at the renal level. In the laboratory, serum anti-C1q antibody levels have become an important tool for monitoring and management of this disease. This study evidences the levels of anti-C1q as a marker of renal involvement in patients with SLE. Patients and methods: The study wa...
Mar 25, 2025Open Access
Background: Malaria is the leading cause of hospital admission in Africa and constitutes the greatest disease burden in the region. More than one hundred nations are affected worldwide with children and pregnant women being mostly vulnerable. Children under the age of five years suffer severe forms. Malaria is said to be severe when the acute illness is associated with a life-threatening event(s). Several organ systems including the kidney can be involved. In most cases, s...
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