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Apr 22, 2026Open Access
Background: Left ventricular hypertrophy (LVH) is an early marker of cardiac involvement and a predictor of heart failure and mortality. This study aimed to determine the incidence of LVH, describe its progression trajectory after initiation of antiretroviral therapy (ART), and identify risk factors for LVH among people living with HIV (PLHIV). Methods: This retrospective cohort study included 154 adults living with HIV who were followed at the University Clinics of Kinshasa between 2000 and 200...
Sep 04, 2024Open Access
Introduction: It is complicated for regulation of growth hormone (GH) secretion. Herein, it is considered the effects of slow-wave sleep (SWS) on GH secretion and related homeostatic aging, and their implications to other complicated GH secretions. Methods: It was best and most convincing to integratively review the literatures in various fields, especially the relationship among GH, SWS, aging, evolution, etc., and then discuss and summarize to deal with such a...
Jun 17, 2022Open Access
In May 2016, it was proposed by the US athletes of the National Basketball Association (NBA) on television that the nociceptive-sympathetic coupling be required for pain sensations. Later, it was demonstrated that, via the activation of sympathetic outputs directly by the nociceptive neurons in laminae I and V of the dorsal spinal horn as well as those in periaqueductal grey (PAG) of brain, it was completed the nociceptive-sympathetic coupling in vertebrates. In this article, for the evolutionar...
Sep 17, 2019Open Access
Relaxation is becoming increasingly important in modern stressful times. Besides special psychological practices or consuming pharmaceuticals, one can achieve a more relaxed state also by applying an appropriate magnetic field stimulation of the head (low-intensity rTMS). Following the entrain-ment model, we did the research using carefully chosen frequencies of modest MF intensity that followed the principles of clinical trials. ...
Mar 15, 2018Open Access
In silico analysis can be useful to infer about the
horizontal gene transfer (HGT) as well as to deduce about the evolutionary
relations of catabolic genes. In this study, we performed the analysis of two
housekeeping genes (fabD and rpoD) and two catabolic gene ...
Jan 23, 2017Open Access
In contemporary, established biology life
is almost exclusively treated as a molecular phenomenon. Therefore, the mystery of the origin
of life is sought in molecular terms and processes. But according to certain advanced
researches and considerations, life
has also other essential “ingredients”: active and diffused organized
information and a specific physical as well as physicochemical state of matter
characterized ...
Feb 03, 2016Open Access
In this article, it is newly suggested the regulation from nutrient
gradient on both cell metabolic state and expressional gene classes as the
conserved mechanism differentiating the cell fates for formation of the three
germ layers of gastrula in animals. As a new theory, it is supported by the totipotency
and pluripotency of early embryonic cells and cultured stem cells to be
regulated by nutrients, as well as by the universal formation of nutrient
gradient during gastrulation in various anima...
Jun 25, 2015Open Access
In this article, it is pointed out with integrative analysis that organogenesis
manifests limitation in time and possession of termination, while infinite cell
proliferation called as cancer and tumor is lethal. Besides, it is reversely demonstrated
from a few notable constant outgrowing skin derivatives that termination is
required for organogenesis inside the animal. Accordingly, it is suggested that
the requirement for organogenetic termination would be the new intrinsic
constraint for animal...
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