Objectives: The objective of this study is to determine the prevalence of Candida albicans in a population of Moroccan completely edentulous patients before and after prosthetic rehabilitation. Materials and Methods: Sixteen completely edentulous patients who consulted the CCTD in Casablanca for prosthetic rehabilitation. Samples were collected using sterile swabs prior to denture insertion from saliva, the maxillary mucosa, and the mandibular mucosa. Samples were collected at 2 and 4 months after prosthesis placement from saliva, the maxillary mucosa, the mandibular mucosa, the maxillary prosthesis, and the mandibular prosthesis. These samples were cultured in Petri dishes using Sabouraud medium. Colony isolates were identified using the Api Candida gallery. Results: Identification confirmed the presence of Candida albicans in the samples collected. The prevalence of Candida albicans was higher at T2 (4 months after denture insertion) than at T0 (before denture insertion) at all sampling sites. Conclusion: The prevalence of Candida albicans is significantly higher among edentulous individuals who wear dentures than among edentulous individuals who do not wear dentures. The combination of factors such as denture wear and reduced salivary flow contributes to the creation of a microenvironment conducive to the growth of Candida albicans. These results underscore the crucial importance of maintaining rigorous oral and denture hygiene to minimize fungal colonization and associated complications. Regular dental care and patient education on proper cleaning techniques are essential for reducing the risk of Candida albicans-related infections.
Cite this paper
Abidi, H. E. A. E. , Ghazzar, F. Z. , Zaim, N. and Bellemkhannate, S. (2026). Oral Candida albicans Colonization in Completely Edentulous Individuals before and after Complete Denture Rehabilitation. Open Access Library Journal, 13, e16095. doi: http://dx.doi.org/10.4236/oalib.1116095.
Martins, M., Henriques, M., Ribeiro, A.P., Fernandes, R., Gonçalves, V., Seabra, Á., <i>et al</i>. (2010) Oral Candida Carriage of Patients Attending a Dental Clinic in Braga, Portugal. <i>Revista</i><i> Iberoamericana de </i><i>Micología</i>, 27, 119-124. <br>https://doi.org/10.1016/j.riam.2010.03.007
Fajri, L., Benfdil, F., Merzouk, N., El Mohtarim, B. and Abdedine, A. (2008) Diagnostic et Gestion des Lésions Muqueuses d’origine Prothétique Chez L’édenté Complet. <i>Actualités</i> <i>Odonto</i>-<i>Stomatologiques</i>, 243, 225-238. <br>https://doi.org/10.1051/aos:2008033
Al-Mobeireek, A. (2003) Qualitative Changes in Oral Flora before and after the Insertion of Removable Prosthesis. <i>Pakistan Oral & D</i><i>ental Journal</i>, 23, 51-56.
Marsh, P.D., Percival, R.S. and Challacombe, S.J. (1992) The Influence of Denture-Wearing and Age on the Oral Microflora. <i>Journal</i> <i>of</i> <i>Dental</i> <i>Research</i>, 71, 1374-1381. <br>https://doi.org/10.1177/00220345920710070501
Daniluk, T., Tokajuk, G., Stokowska, W., Fiedoruk, K., Sciepuk, M., Zaremba, M.L., <i>et al</i>. (2006) Occurrence Rate of Oral <i>Candida </i><i>albicans</i> in Denture Wearer Patients. <i>Advances in Medical Sciences</i>, 51, 77‑80.
Wei, X., Zhou, X.D., Li, B.Q., Li, J.Y. and Xiao, X.R. (2006) Correlation of Oral <i>Candida spp</i>. and Denture-Wearing in Healthy Elderly. <i>West China Journal of Stomatology</i>, 24, 39‑41+47.
Jafari, A.A. (2014) The Comparison of Predominant Oral Micro-Flora in Subjects with and without Complete Denture Referred to Yazd Dentistry Department. <i>Journal of Community Health Research</i>, 3, 196-204.
Nair, V.V., Karibasappa, G.N., Dodamani, A. and Prashanth, V.K. (2016) Microbial Contamination of Removable Dental Prosthesis at Different Interval of Usage: An in Vitro Study. <i>The</i> <i>Journal</i> <i>of</i> <i>Indian</i> <i>Prosthodontic</i> <i>Society</i>, 16, 346-351. <br>https://doi.org/10.4103/0972-4052.176536
Yanishen, I.V. (2017) Microecology of the Oral Cavity in the Period of Adaptation to Removable Dentures. <i>International Scientific and</i> <i>Practical Conference</i>, 6, 13-17.
Mousa, M.A., Lynch, E. and Kielbassa, A.M. (1985) Denture-Related Stomatitis in New Complete Denture Wearers and Its Association with Candida Species Colonization: A Prospective Case-Series. <i>Quintessence International</i>, 51, 554‑565.
Avon, S.L. (2019) Comparaison de deux techniques de prélèvement <i>in </i><i>V</i><i>ivo</i> et la dynamique du développement de la plaque prothétique chez des porteurs de prothèse sains et atteints de stomatite prothétique associée à <i>Candida </i><i>albicans</i>. Université de Laval.
Carvalho, J.F., Maurício, P.J., Proença, L. and do Nascimento, T.M.S. (2011) Changes in Oral-Microflora of Patients with Prosthesis on Hygiene Protocol. <i>Journal of Dental Research</i>, 90, 477.
Nikhath, S., Ahmed, S., Nandini, V.V., Lathief, J. and Boruah, S. (2023) An <i>in </i><i>Vitro</i> Comparison of Microbial Adhesion on Three Different Denture Base Materials and Its Relation to Surface Roughness. <i>Cureus</i>, 15, e37085.
