Objective: To explore the correlation between abdominal Visceral Fat (VAT) area, Subcutaneous Fat (SAT) area and Aortic Dissection (AD) based on Quantitative CT (QCT). Methods: A total of 99 patients with AD diag-nosed by CT angiography from January 2019 to April 2023 were retrospec-tively collected as the dissection group. The subjects were frequen-cy-matched by age and gender. From the patients who underwent whole ab-dominal CT plain scan for non-specific abdominal pain, routine physical examination or other non-cardiovascular emergencies during the same peri-od, 85 subjects without AD were selected as the control group. Their absence of aortic disease was confirmed by reviewing the imaging data and medical records. Collect the general clinical data of the two groups, and measure the liver fat fraction (Fat%-QCT) and the area of abdominal VAT and SAT at the L2/3 intervertebral space level based on QCT. Conduct a multivariate Lo-gistic regression analysis to identify the independent factors associated with the occurrence of AD. Results: Univariate analysis showed that the propor-tions of smoking history, drinking history, and hypertension in the dissec-tion group were significantly higher than those in the control group (all P < 0.05), as were Fat%-QCT, VAT area, and SAT area. Spearman rank correlation analysis showed that smoking history, drinking history, hypertension, Fat%-QCT, SAT area, and VAT area were positively correlated with AD oc-currence (R = 0.349, 0.366, 0.427, 0.185, 0.276, 0.227). Multivariate Logistic regression analysis showed that smoking history, drinking history, hyper-tension, and SAT area (OR = 0.238, 0.150, 0.138, 1.010) were independent risk factors for AD occurrence (all P < 0.05), while VAT area (P = 0.486) and Fat%-QCT (P = 0.105) were not independent influencing factors. Conclusion: An increase in abdominal subcutaneous fat area is independently as-sociated with the occurrence of aortic dissection and is a new independent risk indicator in addition to traditional risk factors (smoking, drinking, and hypertension). Controlling body weight and reducing abdominal subcutaneous fat accumu-lation may help reduce the risk of AD.
Cite this paper
Liu, X. and Wang, J. (2026). A Study on the Correlation between Abdominal Subcutaneous Fat Area and Aortic Dissection Based on Quantitative CT. Open Access Library Journal, 13, e15126. doi: http://dx.doi.org/10.4236/oalib.1115126.
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