Background: Collagenous Fibroma (CF) of the nail, particularly the finger, is exceedingly uncommon. Although uncommon, they should be included in the differential diagnosis of nail abnormalities. Early diagnosis and complete surgical excision lead to an excellent prognosis with a minimal risk of recurrence. Objective: To raise awareness of the rarity of this condition to improve its early diagnosis and management. Case Report: A 72-year-old woman presented with a painless, slowly enlarging subcutaneous mass for 2 years at the base of the right middle fingernail. She was treated surgically under digital block anesthesia and followed up for 12 months. Results: The patient recovered without complications, and follow-up visits showed no recurrence at 12 months post operative upon complete regrowth, clinical examination revealed well defined longitudinal groove. Conclusion: This case highlights the delayed presentation and the importance of complete excision of collagenous fibroma of the nail matrix, which can lead to a favorable prognosis when effectively managed.
Cite this paper
Ahmed, A. F. , Wu, L. and Zhong, J. (2026). A Case Report of Collagenous Fibroma of the Fingernail. Open Access Library Journal, 13, e14815. doi: http://dx.doi.org/10.4236/oalib.1114815.
Gao, S., Cai, Q., Yao, W., Wang, J., Zhang, P. and Wang, X. (2013) Desmoplastic (Collagenous) Fibroma of the Femur: A Case Report and Review of the Literature. Oncology Letters, 6, 1285-1288. https://doi.org/10.3892/ol.2013.1535
Yasuda, T., Amano, K., Kawamura, K., Cho, J., Kogo, M. and Tanaka, S. (2023) A Case of a Massive Desmoplastic Fibroblastoma on the Mandibular Gingiva. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 35, 172-177. https://doi.org/10.1016/j.ajoms.2022.08.012
Abzug, J.M. and Cappel, M.A. (2012) Benign Acquired Superficial Skin Lesions of the Hand. The Journal of Hand Surgery, 37, 378-393. https://doi.org/10.1016/j.jhsa.2011.11.025
Sung, Y.J. and Koo, J.B. (2011) Collagenous Fibroma (Desmoplastic Fibroblastoma) of the Finger: A Case Report. Journal of the Korean Society of Radiology, 64, Article 67. https://doi.org/10.3348/jksr.2011.64.1.67
Kim, J.H., Oh, D.Y., Kim, S.W., Lee, J.H., Ahn, S.T. and Rhie, J.W. (2012) Desmoplastic Fibroblastoma of the Finger Tip in an Adult. Archives of Plastic Surgery, 39, 84-86. https://doi.org/10.5999/aps.2012.39.1.84
Gong, L., Liu, W., Ding, Y., Geng, Y., Sun, X. and Huang, X. (2018) Diagnosis and Differential Diagnosis of Desmoplastic Fibroblastoma by Clinical, Radiological, and Histopathological Analyses. Chinese Medical Journal, 131, 32-36. https://doi.org/10.4103/0366-6999.221274
Miettinen, M. and Fetsch, J.F. (1998) Collagenous Fibroma (Desmoplastic Fibroblastoma): A Clinicopathologic Analysis of 63 Cases of a Distinctive Soft Tissue Lesion with Stellate-Shaped Fibroblasts. Human Pathology, 29, 676-682. https://doi.org/10.1016/s0046-8177(98)90275-1
Nishio, J., Iwasaki, H., Nishijima, T. and Kikuchi, M. (2002) Collagenous Fibroma (Desmoplastic Fibroblastoma) of the Finger in a Child. Pathology International, 52, 322-325. https://doi.org/10.1046/j.1440-1827.2002.01351.x
Nakayama, S., Nishio, J., Aoki, M., Nabeshima, K. and Yamamoto, T. (2021) An Update on Clinicopathological, Imaging and Genetic Features of Desmoplastic Fibroblastoma (Collagenous Fibroma). In Vivo, 35, 69-73. https://doi.org/10.21873/invivo.12233