This paper describes a male infant in whom linear growth slowed after taking Leonurus artemisia motherwort tablets during his mother’s breastfeeding period. Examination ruled out common endocrine, nutritional, and genetic causes, and the case was therefore classified as idiopathic short stature. It is concluded that bioactive compounds through milk may have disrupted signalling pathways related to growth. It advocates minimizing the use of drugs during breastfeeding.
Cite this paper
Zhang, J. (2025). Analysis of a Case of Infant Growth Retardation Caused by a Lactating Mother’s Use of Motherwort. Open Access Library Journal, 12, e13670. doi: http://dx.doi.org/10.4236/oalib.1113670.
Chen, W., Liu, H., Liu, J., et al. (2019) Etiology and Genetic Diagnosis of Short Stature in Children. Chinese Journal of Contemporary Pediatrics, 21, 381-386.
Gagnier, J.J., Kienle, G., Altman, D.G., Moher, D., Sox, H. and Riley, D. (2013) The CARE Guidelines: Consensus-Based Clinical Case Reporting Guideline Development. Global Advances in Health and Medicine, 1, 38-43.
Yang, T.L. (2023) Clinical Efficacy of Oxytocin Combined with Motherwort Granules in the Treatment of Postpartum Vaginal Bleeding. Medical Journal of Liaoning, 37, 50-52.
Li, Z. and Liu, L. (2015) Clinical Analysis of Compound Yimu Capsules in the Treatment of Postpartum Abdominal Pain. Journal of North Pharmacy, 12, 74-75.
Yang, Y., Zhang, L.L. and Sheng, F.Y. (2022) Etcpotential Molecular Mechanism Study of Motherwort in the Treatment of Postpartum Abdominal Pain Based on Network Pharmacology. Natural Product Research and Development, 34, 294-304.
Xia, W., Zhou, H., Wang, Y., et al. (2020) Motherwort Injection in Preventing Post-Abortion Hemorrhage after Induced Abortion: A Multi-Center, Prospective, Randomized Controlled Trial. Explore: The Journal of Science and Healing, 16, 110-115. https://doi.org/10.1016/j.explore.2019.08.004
Li, C.L. and Wang, B.L. (2018) Analysis of the Mechanism of Action of Motherwort Based on Network Pharmacology. Chinese Journal of Information on Traditional Chi-nese Medicine, 25, 102-106.
Qiao, J.J., Wu, Q.N., Xue, M., et al. (2018) Advances in the Study of Chemical Constitu-ents and Pharmacological Effects of Motherwort. Chinese Herbal Medicine, No. 23, 5691-5704.
Liu, Z.Z., Song, Y.P., Zheng, X.D., et al. (2023) Effect of Motherwort on Chemosensitivity of Breast Cancer Cells by Regulating JAK2/STAT3 Sig-naling Pathway. Chinese Journal of Birth Health & Heredity, 31, 1973-1979.
Huang, C., Fang, X.G., Chen, L., et al. (2023) The Effect of Motherwort Alkaloids Regulating the Akt/MDM2/P53 Signaling Pathway on the Malignant Biological Behavior of Glioma Cells. Journal of Difficult Diseases, 22, 1090-1097.
Liang, Y. and Luo, X.P. (2020) Challenges and Opportunities for Genetic Diagnosis of Children with Short Stature. Chinese Journal of Pe-diatrics, 58, 443-446.
