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Larger Scale Photochemical Bromination of Toluene, 1-Methylnaphthalene and Acetophenone in Aqueous Biphasic System and Applications of the Crude Products in Synthesis

DOI: 10.4236/oalib.1112872, PP. 1-21

Subject Areas: Organic Chemistry

Keywords: Alkylation, Anticancer, Photochemical Bromination, Phase Transfer Catalysis

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Abstract

Photochemical bromination of toluene up to 300 mmol per run in aqueous biphasic system formed benzyl bromide of sufficient purity to be used directly for benzylations without any purification. 1-Methylnaphthalene and acetophenone react similarly. An approach to (R) and (S) 1-O-triphenylmethyl-glycerol is presented based on L- and D-xylose.

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Lira, K. K. D. M. , Santos, H. N. L. D. , Nazarenko, A. Y. , Siqueira, E. C. D. and Doboszewski, B. (2025). Larger Scale Photochemical Bromination of Toluene, 1-Methylnaphthalene and Acetophenone in Aqueous Biphasic System and Applications of the Crude Products in Synthesis. Open Access Library Journal, 12, e2872. doi: http://dx.doi.org/10.4236/oalib.1112872.

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