Purpose: To evaluate the visual, refractive, and topographic improvement after deep anterior lamellar keratoplasty (DALK) in keratoconic patients. Setting: Benghazi Eye Teaching Hospital. Design: A prospective cohort study was done in the period from November 2023 to January 2024 and included 30 keratoconic eyes of 30 patients who underwent DALK. Methods: Thirty keratoconic eyes from 30 patients who underwent DALK. Preoperative data include uncorrected visual acuity (UCVA) and corrected distance visual acuity (CDVA), keratometry, and Q value. Postoperative UCVA and CDVA were evaluated at 7, 30, 60, and 90 days, with CDVA, keratometry, and Q-value using topography images at 90 days postoperatively. Inclusion Criteria: Moderate to severe keratoconus with the steepest K reading > 45 D based on the keratoconus study; age from 17 to 57 years; patients who can keep up follow-up for 3 months after surgery; minimum corneal thickness of 260 μm at the thinnest corneal location. Exclusion Criteria: Pregnancy or nursing, history of hydrops, retinal or macular diseases, optic nerve pathologies, trauma, or amblyopia, and evidence of infectious corneal disease in the eye to be operated on. Results: There were statistically improved postoperative compared to preoperative parameters in UCVA and CDVA at the first week (P < 0.05). Similarly, at 30, and 60 days. As well as at 90 days, parameters improved in the UCVA, CDVA, refractive, and topographic data. Conclusion: DALK is efficient for treating keratoconus. It improves UCVA and CDVA in patients with anterior corneal pathology. Faster wound healing is associated with a better donor-recipient fit.
Cite this paper
Elkeilani, E. M. , Elzarrug, H. K. H. A. and Yousif, M. O. (2024). Visual Outcome after Lamellar Keratoplasty at Benghazi Eye Teaching Hospital. Open Access Library Journal, 11, e2283. doi: http://dx.doi.org/10.4236/oalib.1112283.
Abdelaal, A.M., Alqassimi, A.H., Malak, M., Hijazi, H.T., Hadrawi, M. and Khan, M.A. (2021) Indications of Keratoplasty and Outcomes of Deep Anterior Lamellar Keratoplasty Compared to Penetrating Keratoplasty. Cureus, 13, e13825. https://doi.org/10.7759/cureus.13825
Weed, K.H., McGhee, C.N.J. and MacEwen, C.J. (2005) Atypical Unilateral Superior Keratoconus in Young Males. Contact Lens and Anterior Eye, 28, 177-179. https://doi.org/10.1016/j.clae.2005.10.002
Romano, V., Iovieno, A., Parente, G., Soldani, A.M. and Fontana, L. (2015) Long-Term Clinical Outcomes of Deep Anterior Lamellar Keratoplasty in Patients with Keratoconus. American Jour-nal of Ophthalmology, 159, 505-511. https://doi.org/10.1016/j.ajo.2014.11.033
Reinhart, W.J., Musch, D.C., Jacobs, D.S., Lee, W.B., Kaufman, S.C. and Shtein, R.M. (2011) Deep Anterior Lamellar Keratoplasty as an Alternative to Penetrat-ing Keratoplasty: A Report by the American Academy of Ophthalmology. Ophthalmology, 118, 209-218. https://doi.org/10.1016/j.ophtha.2010.11.002
Borderie, V.M., Sandali, O., Bullet, J., Gaujoux, T., Touzeau, O. and Laroche, L. (2012) Long-Term Results of Deep Anterior Lamellar versus Penetrating Keratoplasty. Ophthalmology, 119, 249-255. https://doi.org/10.1016/j.ophtha.2011.07.057
Koytak, A., Kubaloglu, A., Sari, E., Akyol, S., Kurnaz, E. and Ozerturk, Y. (2012) Corneal Endothelium after Deep Anterior Lamellar Keratoplasty and Penetrating Keratoplasty for Ker-atoconus: A Four-Year Comparative Study. Indian Journal of Ophthalmology, 60, 35-40. https://doi.org/10.4103/0301-4738.90490
Anwar, M. and Teichmann, K.D. (2002) Deep Lamellar Keratoplasty: Surgical Techniques for Anterior Lamellar Keratoplasty with and without Baring of Descemet’s Membrane. Cornea, 21, 374-383. https://doi.org/10.1097/00003226-200205000-00009
Lee, B.W. and Mathys, K.C. (2009) Traumatic Wound Dehiscence after Deep Anterior Lamellar Keratoplasty. Journal of Cataract and Refractive Surgery, 35, 1129-1131. https://doi.org/10.1016/j.jcrs.2009.01.037
Shimazaki, J. (2000) The Evolution of Lamellar Keratoplasty. Current Opinion in Ophthalmology, 11, 217-223. https://doi.org/10.1097/00055735-200008000-00002
Edwards, M., McGhee, C.N. and Dean, S. (2001) The Genetics of Keratoconus. Clinical & Experimental Ophthalmology, 29, 345-351. https://doi.org/10.1046/j.1442-9071.2001.d01-16.x
Nielsen, K., Hjortdal, J., Aagaard Nohr, E. and Ehlers, N. (2007) Incidence and Prevalence of Keratoconus in Denmark. Acta Ophthalmologica Scandinavica, 85, 890-892. https://doi.org/10.1111/j.1600-0420.2007.00981.x
Pajic, B., Müller, J., Pajic-Eggspuehler, B. and Ljubic, J. (2010) Lamellar Keratoplasty for Keratoconus. In: Garg, A., Malyugin, B., Pajic, B., et al., Eds., Surgical Techniques in Ophthalmolo-gy: Corneal Surgery, Jaypee Brothers Medical Publishers, 45-48. https://doi.org/10.5005/jp/books/11369_8
Vishak, G., Goins, K.M. and Afshari, N.A. (2007) Deep Anterior Lamellar Keratoplasty. American Academy of Ophthalmology. https://www.aao.org/eyenet/article/deep-anterior-lamellar-keratoplasty
Riss, S., Heindl, L.M., Bachmann, B.O., Kruse, F.E. and Cursiefen, C. (2012) Pentacam-Based Big Bubble Deep Anterior Lamellar Keratoplasty in Patients with Keratoconus. Cornea, 31, 627-632. https://doi.org/10.1097/ico.0b013e31823f8c85
Arantes, J.C.D., Coscarelli, S., Ferrara, P., Araújo, L.P.N., ávila, M. and Torquetti, L. (2017) Intrastromal Corneal Ring Segments for Astigmatism Correc-tion after Deep Anterior Lamellar Keratoplasty. Journal of Ophthalmology, 2017, Article 8689017. https://doi.org/10.1155/2017/8689017
Qin, Q., Yang, L., He, Z. and Huang, Z. (2017) Clinical Application of TICL Implantation for Ametropia Following Deep Anterior Lamellar Keratoplasty for Keratoconus: A CONSORT-Compliant Article. Medicine, 96, e6118. https://doi.org/10.1097/md.0000000000006118
Lu, Y., Shi, Y.H., Yang, L.P., Ge, Y.R., Chen, X.F., Wu, Y. and Huang, Z.P. (2014) Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty for Keratoconus and Keratectasia. International Journal of Ophthalmology, 7, 638-643. https://doi.org/10.3980/j.issn.2222-3959.2014.04.09
Huang, Z., Lu, Y., Chen, X., Yang, L. and Xue, C. (2016) Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty with Big-Bubble Technique for Keratoconus. Indian Journal of Ophthalmology, 64, 639-642. https://doi.org/10.4103/0301-4738.194326