All Title Author
Keywords Abstract

Publish in OALib Journal
ISSN: 2333-9721
APC: Only $99

ViewsDownloads

Management of a Case of Male Breast Cancer in a Reference Hospital in Yaoundé: Clinical Case and Review of the Literature

DOI: 10.4236/oalib.1111734, PP. 1-6

Subject Areas: Gynecology & Obstetrics

Keywords: Management, Breast Cancer, Male

Full-Text   Cite this paper   Add to My Lib

Abstract

Breast cancer in men is a rare pathology. It represents approximately 1% of breast cancers and 1.2% of male cancers. We report the clinical case of a 54-year-old man referred from a health facility for the management of a non-painful right breast swelling that had been present for 2 months. A breast ultrasound was performed revealing an increase in the glandular parenchyma of the right breast, with the absence of a mass or nodule, classified ACR BI-RADS 2 (American College of Radiology—Breast Imaging Reporting & Data System). There was no significant past medical history. Clinical examination on admission revealed breast asymmetry on inspection, with the right breast being increased in size. On palpation, there was right retro-areolar tumefaction of about 3 cm, and right peri-areolar stiffness. Both breasts were non-tender, and there was no discharge nor palpable axillary lymph nodes bilaterally. The diagnosis of right gynecomastia was made with a differential of right breast cancer. A breast biopsy was done and histopathology analysis was in favor of a carcinoma. A right total mastectomy with axillary lymph node dissection was performed with favorable postoperative outcomes. The histopathological and immuno-histochemical analysis of the surgical specimen revealed foci of atypical ductal hyperplasia associated with cylindrical metaplasia with oestrogen, progesterone and HER2 (Human epidermal growth factor Receptor 2) receptors. The patient was put on Tamoxifen 25 mg 1 tab/day and adjuvant radio-chemotherapy started.

Cite this paper

Mol, H. L. , Ntsama, J. A. M. , Mendibi, S. , Mbia, C. H. and Ndoua, C. C. N. (2024). Management of a Case of Male Breast Cancer in a Reference Hospital in Yaoundé: Clinical Case and Review of the Literature. Open Access Library Journal, 11, e1734. doi: http://dx.doi.org/10.4236/oalib.1111734.

References

[1]  Elbachiri, M., Fatima, S., Bouchbika, Z., Benchekroun, N., Jouhadi, H., Tawfiq, N., et al. (2017) Cancer du sein chez l’homme: à propos de 40 cas et revue de la lit-térature. Pan African Medical Journal, 28, Article 287. https://doi.org/10.11604/pamj.2017.28.287.13527
[2]  Giordano, S.H., Cohen, D.S., Buzdar, A.U., Perkins, G. and Hortobagyi, G.N. (2004) Breast Carcinoma in Men. Cancer, 101, 51-57. https://doi.org/10.1002/cncr.20312
[3]  Lee, S. (2023) Cancer du sein chez l’homme. Société canadienne du cancer.
[4]  Taber, J., et al. (2010) Male Breast Cancer: Risk Factors, Diagnosis, and Management (Review). Oncology Reports, 24, 1115-1120. https://doi.org/10.3892/or_00000962
[5]  Elketroussi, F. and Benrabah, L. (2018) Profil épidémiologique des cancers du sein masculin à Oran, Algérie. Revue d’épidémiologie et de Santé Publique, 66, S158. https://doi.org/10.1016/j.respe.2018.03.106
[6]  Dabakuyo-Yonli, S., Cottenet, J., Mariet, A.S., Arveux, P. and Quantin, C. (2016) Cancer du sein chez l’homme en France. Revue d’épidémiologie et de Santé Publique, 64, S26. https://doi.org/10.1016/j.respe.2016.01.080
[7]  Weiss, J.R., Moysich, K.B. and Swede, H. (2005) Epidemiology of Male Breast Cancer. Cancer Epidemiology, Biomarkers & Prevention, 14, 20-26. https://doi.org/10.1158/1055-9965.20.14.1
[8]  Schlienger, J.L., Luca, F., Vinzio, S. and Pradignac, A. (2009) Obésité et cancer. La Revue de Médecine Interne, 30, 776-782. https://doi.org/10.1016/j.revmed.2009.04.007
[9]  Fentiman, I.S., Fourquet, A. and Hortobagyi, G.N. (2006) Male Breast Cancer. The Lancet, 367, 595-604. https://doi.org/10.1016/s0140-6736(06)68226-3
[10]  Thomas, D.B., Margarita Jimenez, L., McTieman, A., Rosenblatt, K., Stalsberg, H., Stemhagen, A., et al. (1992) Breast Cancer in Men: Risk Factors with Hormonal Implications. American Journal of Epidemiology, 135, 734-748. https://doi.org/10.1093/oxfordjournals.aje.a116360
[11]  Benchellal, Z., Wagner, A., Harchaoui, Y., Huten, N. and Body, G. (2002) Cancer du sein chez l’homme: à propos de 19 cas. Annales de Chirurgie, 127, 619-623. https://doi.org/10.1016/s0003-3944(02)00816-7
[12]  Alaoui Slimani, K., Deb-bagh, A., Sbitti, Y., Errihani, H. and Ichou, M. (2016) Cancer du sein chez l’homme au Maroc: épidémiologie et facteurs pronostiques. à propos de 140 cas. Gyné-cologie Obstétrique & Fertilité, 44, 636-640. https://doi.org/10.1016/j.gyobfe.2016.08.009
[13]  Laabadi, K., Jayi, S., Alaoui, F.F., Bouguern, H., Chaara, H., Melhouf, M.A., et al. (2013) Cancer du sein de l’homme: à propos de 6 cas. Pan African Medical Journal, 16, Article 70. https://doi.org/10.11604/pamj.2013.16.70.2345
[14]  Hali, F., Khadir, K., Idhammou, W., Bensardi, F., Lefriyekh, M., Benider, A., et al. (2011) Manifesta-tions cutanées du cancer du sein chez l’homme. La Presse Médicale, 40, e483-e488. https://doi.org/10.1016/j.lpm.2011.04.010
[15]  Oger, A.S., Boukerrou, M., Cutuli, B., Campion, L., Rousseau, E., Bussières, E., et al. (2015) Le cancer du sein chez l’homme: Approche épidémiologique, diagnostique, et thérapeutique: étude mul-ticentrique rétrospective à propos de 95 cas. Gynécologie Obstétrique & Fertilité, 43, 290-296. https://doi.org/10.1016/j.gyobfe.2015.02.010
[16]  Bohli, M., Tebra Mrad, S., Zrafi, I. and Bouaouina, N. (2017) Cancer du sein chez l’homme: Quelles particularités? Cancer/Radiothérapie, 21, 701. https://doi.org/10.1016/j.canrad.2017.08.049
[17]  Espié, M. (2020) Le sein, Du Normal Au Pathologique: Etat de L’art. éditions Eska.
[18]  Muir, D., Kanthan, R. and Kanthan, S.C. (2003) Male versus Female Breast Cancers. Archives of Pa-thology & Laboratory Medicine, 127, 36-41. https://doi.org/10.5858/2003-127-36-mvfb
[19]  Cutuli, B., Le-Nir, C.C., Serin, D., Kirova, Y., Gaci, Z., Lemanski, C., et al. (2010) Male Breast Cancer. Evolution of Treatment and Prognostic Factors: Analysis of 489 Cases. Critical Reviews in On-cology/Hematology, 73, 246-254. https://doi.org/10.1016/j.critrevonc.2009.04.002
[20]  Fayard, J. (2019) Cancer du sein chez l’homme: Caractéristiques cliniques, radiologiques, histologiques et thé-rapeutiques chez 60 patients. Université de Paris Diderot, 186p.

Full-Text


comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133

WeChat 1538708413