Ischio rectal chordoma is a rare bone tumor. The optimal therapeutic strategy for ischio rectal chordoma remains surgery. This case describes a 32-year-old adult with ischio rectal chordoma. Given the potential impact on quality of life and the technical platform available, the patient did not undergo tumor resection. The patient was treated with exclusive radiotherapy. The patient developed pulmonary metastases three months after the end of radiotherapy. This case highlights a minimally invasive strategy for the treatment of these rare tumors. The radiographic and histopathological features of chordomas are also reviewed, and the various treatment options reported in the literature are discussed.
Cite this paper
Mhirech, S. , Tnifasse, N. , Akotegnon, F. , Kanouni, N. , Medyouni, H. , Chouef, J. , Farhane, F. Z. , Alami, Z. and Bouhafa, T. (2024). Ischio Rectal Chordoma: A Case Report and Literature Review. Open Access Library Journal, 11, e1458. doi: http://dx.doi.org/10.4236/oalib.1111458.
Mcmaster, M.L., Goldstein, A.M., Bromley, C.M., Ishibe, N. and Parry, D.M. (2001) Chordoma: Incidence and Survival Patterns in the United States, 1973-1995. Cancer Causes Control, 12, 1-11. https://doi.org/10.1023/A:1008947301735
Eriksson, B., Gunterberg, B. and Kindblom, L.-G. (2009) Chordoma: A Clinicopathologic and Prognostic Study of a Swedish National Series Acta Orthopaedica Scandinavica, 52, 49-58. https://doi.org/10.3109/17453678108991758
Hidebrandt, V. and Feifel, G. (1985) Preoperative Staging of Rectal Cancer by Intrarectal Ultrasound. Diseases of the Colon & Rectum, 28, 42-46. https://doi.org/10.1007/BF02553906
El Khannoussi, B., Harmouch, A., Boumezaoued, M., Maher, M. and Sefiani, S. (2010) Les Chordomes: A Propos De Sept Cas. Oncologie, 12, S66-S70. https://doi.org/10.1007/s10269-010-1966-8
Pillaia, S. and Govenderb, S. (2018) Sacral Chordoma: A Review of Literature. Journal of Orthopaedics, 15, 679-684. https://doi.org/10.1016/j.jor.2018.04.001
Brunel, H., Peretti-Viton, P. and Benguiguicharmeau, V. (2002) L’IRM: Un examen indispensable dans la prise en charge des chordomes sacrococcygiens étude de cinq cas. The Neuroradiology Journal, 29, 15-22.
Georgea, B., Bressona, D., Bouazzaa, S., Froelicha, S., Mandonneta, E., Hamdia, S., Orabia, M., Polivkab, M., Cazorlab, A., Adle-Biassetteb, H., Guichardc, J.-P., Duetd, M., Gayate, E., Valléee, F., Canovaf, C.-H., Rietf, F., Bollef, S., Calugaruf, V., Dendalef, R., Mazeronf, J.-J., Feuvretf, L., Boissierf, E., Vignotf, S., Pugetg, S., Sainte-Roseg, C. And Beccariag, K. (2014) Les Chordomes. Neurochirurgie, 60, 63-140. https://doi.org/10.1016/j.neuchi.2014.02.003
Dauty, M.R., Fame, A., Le Neels, J.C., et al. (2000) Chordome Sacré: Une Pathologie Rare. Annals of Physical and Rehabilitation Medicine, 43, 84-88. https://doi.org/10.1016/S0168-6054(00)88732-2
Preda, L., Stoppa, D., Fiore, M.R., Fontana, G., Camisa, S., Sacchi, R., et al. (2018) Mri Evaluation of Sacral Chordoma Treated with Carbon Ion Radiotherapy. Alone Radiotherapy and Oncology, 128, 203-208. https://doi.org/10.1016/j.radonc.2017.11.029
Catton, C., O’sullivan, B., Bell, R., Laperriere, N., Cummings, B., Fornasier, V. and Wunder, J. (1996) Chordoma: Long-Term Follow-Up after Radical Photon Irradiation. Radiotherapy and Oncology, 41, 67-72. https://doi.org/10.1016/S0167-8140(96)91805-8
Brada, M., Pijls-Johannesma, M. and De Ruysscher, D. (2007) Proton Therapy in Clinical Practice: Current Clinical Evidence. Journal of Clinical Oncology, 25, 965-970. https://doi.org/10.1200/JCO.2006.10.0131
Schulz-Ertner, D., Karger, C.P., Feuerhake, A., Nikoghosyan, A., Combs, S.E., Jakel, O., et al. (2007) Effectiveness of Carbon Ion Radiotherapy in the Treatment of Skull Base Chordomas. International Journal of Radiation Oncology, Biology, Physics, 68, 449-457. https://doi.org/10.1016/j.ijrobp.2006.12.059
Stacchiotti, S., Longhi, A., Ferraresi, V., Grignani, G., Comandone, A., Stupp, R., et al. (2012) Phase Ii Study of Imatinib in Advanced Chordoma. Journal of Clinical Oncology, 30, 914-920. https://doi.org/10.1200/JCO.2011.35.3656
Stacchiotti, S., Marrari, A., Tamborini, E., Palassini, E., Virdis, E., Messina, A., et al. (2009) Response to Imatinib Plus Sirolimus in Advanced Chordoma. Annals of Oncology, 20, 1886-1894. https://doi.org/10.1093/annonc/mdp210
