Identification, Prevalence, and Outcome of Complex Percutaneous Coronary Intervention (C-PCI)—A Single Center Experience

Introduction: Despite the shift in PCI application, the underlying criteria of complex PCI and its impact on clinical outcomes remain unexplained. Methods: Single-center retrospective observational study of complex PCI characteristics and 1-year outcome. Complex PCI was defined as any of the following: three-vessel disease, bifurcation lesion, left main disease, and moderate to severe calcification by angiography and CTO. Results: The study cohort includes 551 patients who had PCI over a two-month period. 101 (20%) of all patients fulfilled the criteria for complex PCI: 20% have 3VD, 33% have LM disease, 38% have bifurcation, 43% have severe Calcification and 35% have CTO. Combined MACE was more common in C-PCI (40% vs 12.4% <0.001), all individual components were more common in C-PCI (Repeated Revascularization 7.9%Vs 3.7%, P 0.071), Rehospitalization for ACS (1.9% vs 2.2%, p 0.8), Recurrent Angina (9% vs 8%, p 0.071), and HF (7% vs 3.7%, p 0.161). Conclusion: Complex PCI is prevalent in everyday practice (20% of total patients) across all clinical presentations, age groups, and gender. The consequence is dismal.