All Title Author
Keywords Abstract

Publish in OALib Journal
ISSN: 2333-9721
APC: Only $99


Study of Precancerous Cervical Lesions and Associated Factors among Women Aged between 18 and 65 Years in Koumpentoum (Senegal)

DOI: 10.4236/oalib.1109508, PP. 1-11

Subject Areas: Women’s Health, Gynecology & Obstetrics

Keywords: Cervix, Cancer, Screening, Koumpentoum, Senegal

Full-Text   Cite this paper   Add to My Lib


Introduction: Cervical cancer can be prevented by papillomavirus vaccination and screening for precancerous lesions. Initiated in the district in 2018, screening has never been studied. The objective of this research was to investigate the frequency of precancerous lesions and associated factors. Methods: This was a descriptive and analytical cross-sectional study. Data were collected from screening registers. Sociodemographic characteristics, medical history, macroscopic data and therapeutic aspects were explored. Logistic regression was used in the multivariate analysis. Results: A total of 385 women aged between 18 and 65 years were included. Almost all (95.58%) were married. The majority (79.48%) had no formal education. Almost all (91.17%) had no income-generating activity. The average age was (30 ± 9.68) years. The median age was 30 years. The frequency of sexually transmitted infections was (29.35%; 95% CI: 25.02 - 34.09) and that of precancerous lesions was (5.45%; 95% CI: 3.59 - 8.19). Factors significantly associated with the presence of precancerous cervical lesions were: age ≥ 40 years (ORa = 17.52 (4.51 - 67.14); p < 0.001) and the history of sexually transmitted infections (ORa = 10.15 (3.46 - 29.85); p < 0.001). Conclusion: Early detection and routine treatment of sexually transmitted infections combined with screening for precancerous cervical lesions in sexually active women can reduce the incidence of cervical cancer.

Cite this paper

Diop, E. H. C. A. , Ndiaye, A. A. and Bop, M. C. (2022). Study of Precancerous Cervical Lesions and Associated Factors among Women Aged between 18 and 65 Years in Koumpentoum (Senegal). Open Access Library Journal, 9, e9508. doi:


[1]  World Health Organization. Cervical Cancer.
[2]  Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R.L., Torre, L.A. and Jemal, A. (2018) Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 68, 394-424.
[3]  Bouassa, R.S.M., Prazuck, T., Lethu, T., Meye, J.F. and Bélec, L. (2017) Cervical Cancer in Sub-Saharan Africa: An Emerging and Preventable Human Papillomavirus Associated Disease. Tropical Medicine and Health, 27, 16-22.
[4]  World Health Organization. Senegal. Source: Globcan 2020.
[5]  Dem, A., Traoré, B., Dieng, M.M., Diop, P.S., Ouajdi, T., Lalami, M.T., Diop, M., Dangou, J.M. and Touré, P. (2008) Les Cancers Gynécologiques et Mammaires à l’Institut du Cancer de Dakar. Cahiers d’études et de Recherches Francophones, 18, 25-29.
[6]  Zhang, J., Qin, Z., Lou, C., Huang, J. and Xiong, Y. (2021) The Efficacy of Vaccination to Prevent Human Papilloma Viruses Infection at Anal and Oral: A Systematic Review and Metaanalysis. Public Health, 196, 165-171.
[7]  World Health Organization. WHO Guidelines for Screening and Treatment of Precancerous Cervical Lesions. (In French)
[8]  Haute Autorité de Santé, H.A. (2013). Dépistage et prévention du cancer du col de l’utérus. Actualisation du référentiel de pratiques de l’examen périodique de santé (EPS). Collège de la Haute Autorité de Santé, Paris.
[9]  World Health Organization. Cervical Cancer Control. Essential Practices Guide. 2nd Edition. (In French)
[10]  Keshavarzi, F., Nankali, A., Fakheri, T., Mansour, R., Rezaei, M., Khoshay, A., Eslamizadeh, N. and Bookani, N.S. (2013) Cervical Visual Inspection with Acetic Acid as an Alternative Screening Test for Cervical Cancer Detection. International Journal of Collaborative Research on Internal Medicine & Public Health, 5, 60-66.
[11]  Catarino, R., Schafer, S., Vassilakos, P., Petignat, P. and Arbyn, M. (2017) Accuracy of Combinations of Visual Inspection Using Acetic Acid or Lugol Iodine to Detect Cervical Precancer: A Meta-Analysis. BJOG: An International Journal of Obstetrics & Gynaecology, 125, 545-553.
[12]  World Health Organization (2020) Global Strategy to Accelerate the Elimination of Cervical Cancer as a Public Health Problem.
[13]  République du Sénégal. Normes et protocoles pour le dépistage du précancer du col de l’utérus et la détection du cancer du sein. Division de lutte contre les maladies non transmissibles. Ministère de la Santé et de l’Action Sociale, République. 52 p.épistage-des-lésions-précancéreuses-du-col-de-l’utérus-et-de
[14]  Economic and Social Situation of the Tambacounda Region in 2019. Agency National Agency of Demography and Statistics. 97 p. (In French)
[15]  Sakamoto, Y., Ishiguro, M. and Kitagawa, G. (1986) Akaike Information Criterion Statistics. D. Reidel, Dordrecht.
[16]  Hosmer, D., Lemeshow, S. and May, S. (2000) Applied Survival Analysis: Regression Modeling of Time to Event Data. Journal of the American Statistical Association, 95, 681-682.
[17]  Thiam, H. (n.d.) Factors Associated with HPV Vaccination in the Region of Kédougou. University Cheikh Anta Diop, Institute of Health and Development, Dakar, 52 p.
[18]  Faye, A., Mbengue, T. and Tall-Dia, A. (2017) Factors Associated with Cervical Cancer Screening in Rural Senegal. Journal of Epidemiology and Public Health, 5, 464-468.
[19]  Guèye, I., Diallo, A.I., Sangho, O., Sawadogo, B. and Tine, J.A.D. (2021) Factors Associated with the Practice of Cervical Cancer Screening in the Health District of Joal, Senegal, 2018: Household Survey. Journal of Interventional Epidemiology and Public Health, 4, 1-11. (In French)
[20]  Cunningham, M.S., Skrastins, E., Fitzpatrick, R., Jindal, P., Oneko, O., Yeates, K., Booth, C.M., Carpenter, J. and Aronson, K.J. (2015) Cervical Cancer Screening and HPV Vaccine Acceptability among Rural and Urban Women Kilimanjaro Region, Tanzania. BMJ Open, 5, e005828.
[21]  Andrianampy, H.A., Rakotomahenina, H., Rakotondraisoa, J.M., Solofomalala, G.D. and Andrianampanalinarivo, H.R. (2014) Cancer du col de l’utérus: Etat des lieux après lancement d’un programme de lutte. Journal Africain du Cancer, 6, 85-90.
[22]  Ngowa, J.D.K., Ngassam, A., Meka, E.N.U., Tsuala, J.F., Tagne, J.C., Sando, Z., Mendounga, J.T.N. and Kasia, J.M. (2015) Screening for Cervical Cancer by Visual Cervical Inspection after Application of Acetic Acid in Yaounde, Cameroon. Health Sciences and Disease, 16, 1-5.
[23]  Tebeu, P.M., Sando, Z., Ndoumba, A., Sandjong, I., Mawech-Fauceglia, P. and Doh, A.S. (2013) Prevalence and Geographical Distribution of Precancerous Lesions of the Uterine Cervix in Cameroon. Journal of Cytology & Histology, 4, Article ID: 1000183.
[24]  Nkegoum, B., Priso, E.B., Mbakop, A. and Bell, E.G. (2001) Precancerous Lesions of the Uterine Cervix in Cameroonian Women. Cytological and Epidemiological Aspects of 946 Cases. Gynaecology Obstetrics & Fertility, 29, 15-20.
[25]  Biaye, B. (2017) Screening for Cervical Cancer Using the Visual Inspection Method (IVA) at the Nabil Choucair Health Centre in Dakar. Dissertation for DES Gynaecology-Obstetrics. Cheikh Anta Diop University of Dakar, Dakar, 300 p.
[26]  Moukassa, D., N’Golet, A., Lingouala, L.G., Eouani, M.L., Samba, J.B., Mambou, J.V. and Taty Pambou, E. (2007) Cervical Cancer Precancerous Lesions in Pointe-Noire: Situation Analysis. Tropical Medicine, 67, 57-60.
[27]  Keita, M., Bourama, C., Saoudatou, T., Samaké, A., et al. (2020) Screening for Pre-Cancerous and Cancerous Lesions and Cancerous Lesions by Visual Tests at Commune VI of the Districtde Bamako. Health Science Disease, 21, 84-89.
[28]  Enquête Démographique et de Santé à Indicateurs Multiples (EDS-MICS) 2010-2011.
[29]  Ly, F., Guéye, N., Samb, N.D., Sow, P.S., Ndiaye, B. and Mahé, A. (2006) Prospective Study of Infections in Dakar, Senegal. Tropical Medicine, 66, 64-68. (In French)
[30]  World Health Organization. Guidelines for the Management of Symptomatic Sexually Transmitted Infections.
[31]  Woodman, C.B.J., Collins, S.I. and Young, L.S. (2007) The Natural History of Cervical HPV Infection: Unresolved Issues. Nature Reviews Cancer, 7, 11-22.
[32]  Hu, S.Y., Rhezake, R., Chen, F., Zhang, X., et al. (2020) Outcomes in Women with Biopsy Confirmed Cervical Intraepithelial Neoplasia Grade 1 or Normal Cervix and Related Cofactors: A 15-Year Population Based Cohort Study from China. Gynecologie and Oncologie, 156, 616-623.
[33]  Thakur, A., Gupta, B., Gupta, A. and Chauhan, R. (2015) Risk Factors for Cancer Cervix among Rural Women of a Hilly State: A Case-Control Study. Indian Journal of Public Health, 59, 45-48.


comments powered by Disqus

Contact Us