Introduction: The volumetric capnography (VCap) is a quick, simple, cheap, and effective test for distal airways. The test is based on the volumetric concentration of expired CO2 and tidal volume (CV) flow over a single exhalation. Literature Review: The exam makes it possible to observe the curve of expired CO2, considering its concentration. These CO2 curves are plotted, showing the inspired volume point by point, and the dead space volume can be calculated among the elimination of CO2 with each breath, showing us the different phases of breathing, seen in slopes, from 1 to 3. Discussion: Several authors found valuable data when comparing volumetric capnography with other established tests, such as spirometry. Conclusion: Despite the countless discoveries using capnography, we still need more tests and comparisons in other pathologies to better understand their most diverse peculiarities. Not forgetting that capnography is a complementary exam. We need other tests, such as computed tomography (CT), to make a diagnosis and define an appropriate treatment for subjects.
Cite this paper
Diniz, O. H. G. (2022). Volumetric Capnography: History, Function and Clinical Uses. Open Access Library Journal, 9, e9175. doi: http://dx.doi.org/10.4236/oalib.1109175.
Kremeier, P., Böhm, S.H. and Tusman, G. (2020) Clinical Use of Volumetric Capnography in Mechanically Ventilated Patients. Journal of Clinical Monitoring and Computing, 34, 7-16. https://doi.org/10.1007/s10877-019-00325-9
Jaffe, M.B. (2008) Infrared Measurement of Carbon Dioxide in the Human Breath: “Breathe-Through” Devices from Tyndall to the Present Day. Anesthesia & Analgesia, 107, 890-904. https://doi.org/10.1213/ane.0b013e31817ee3b3
Balogh, A.L., Petak, F., Fodor, G.H., Tolnai, J., Csorba, Z. and Babik, B. (2016) Capnogram Slope and Ventilation Dead Space Parameters: Comparison of Mainstream and Sidestream Techniques. British Journal of Anaesthesia, 117, 109-117.
https://doi.org/10.1093/bja/aew127
Verscheure, S., Massion, P.B., Verschurem, F., Damas, P. and Magder, S. (2016) Volumetric Capnography: Lessons from the Past and Current Clinical Applications. Critical Care, 20, Article No. 184. https://doi.org/10.1186/s13054-016-1377-3
Romero, P.V., Lucangelo, U. and Lopez, J. (1997) Physiologically Based Index of Volumetric Capnography in Patients Receiving Mechanical Ventilation. European Respiratory Journal, 10, 1309-1315. https://doi.org/10.1183/09031936.97.10061309
Ribeiro, M.Â., Silva, M.T., Ribeiro, J.D., Moreira, M.M., Almeida, C.C., Almeida-Junior, A.A., et al. (2012) Volumetric Capnography as a Tool to Detect Early Peripheric Lung Obstruction in Cystic Fibrosis Patients. The Journal of Pediatrics, 88, 509-517.
Pereira, D.J., Moreira, M.M., Paschoal, I.A., Martins, L.C., Metze, K. and Moreno Junior, H. (2011) Near-Fatal Pulmonary Embolism in an Experimental Model: Hemodynamic, Gasometric and Capnographic Variables. Revista Brasileira de Cirurgia Cardiovascular, 26, 462-468.
Qi, G.-S., Gu, W.-C., Yang, W.-L., Xi, F., Wu, H. and Liu, J.-M. (2014) The Ability of Volumetric Capnography to Distinguish between Chronic Obstructive Pulmonary Disease Patients and Normal Subjects. Lung, 192, 661-668.
https://doi.org/10.1007/s00408-014-9615-4
Schwardt, J.D., Neufeld, G.R., Baumgardner, J.E. and Scherer, P.W. (1994) Noninvasive Recovery of Acinar Anatomic Information from CO2 Expirograms. Annals of Biomedical Engineering, 22, 293-306. https://doi.org/10.1007/BF02368236
Weibel, E.R. (2001) Why Measure Lung Structure? American Journal of Respiratory and Critical Care Medicine, 163, 314-315.
https://doi.org/10.1164/ajrccm.163.2.hh12-00
Hansen, J.E. and Ampaya, E.P. (1975) Human Air Space Shapes, Sizes, Areas, and Volumes. Journal of Applied Physiology, 38, 990-995.
https://doi.org/10.1152/jappl.1975.38.6.990
Schwardt, J.D., Gobran, S.R., Neufeld, G.R., Aukburg, S.J. and Scherer, P.W. (1991) Sensitivity of CO2 Washout to Changes in Acinar Structure in a Single-Path Model of Lung Airways. Annals of Biomedical Engineering, 19, 679-697.
https://doi.org/10.1007/BF02368076
Paschoal, I.A., Mello, M.M., Terzi, R., Pereira, M.C., Hermini, A. and Baird, G. (2002) Capnografia volumétrica na bronquectasia: Obtenção de informações anatômicas acinares de forma não invasiva. Revista Portuguesa de Pneumologia, 8, 504.
Diniz, O.H.G., Pereira, M.C., Da Silva, S.M.D., Santos, M.K., Paschoal, I.A. and Moreira, M.M. (2022) Correlations between Volumetric Capnography and Automated Quantitative Computed Tomography Analysis in Patients with Severe COPD. Journal of Respiration, 2, 13-24. https://doi.org/10.3390/jor2010002
Luiz, L.C., Marson, F.A.L., Almeida, C.C.B., Toro, A.A.D.C., Nucci, A. and Ribeiro, J.D. (2019) Analysis of Motor and Respiratory Function in Duchenne Muscular Dystrophy Patients. Respiratory Physiology & Neurobiology, 262, 1-11.
https://doi.org/10.1016/j.resp.2019.01.009