Context: For several decades, the introduction of AntiRetroViral (ARV) has allowed an improvement in the clinical signs of patients, a spectacular reduction in mortality and morbidity, an extension of life and an improvement in the quality of life of many People Living with HIV (PLHIV). Objective: The objective of this study was to determine the clinical profile of PLHIV starting ARV Treatment in Kinshasa in the era of Dolutegravir. Methods: This study is a descriptive cross-sectional study to determine the clinical profile of PLHIV starting ARV treatment in HIV Outpatient Treatment Centers (OTC) in Kinshasa. Thirteen OTC across the city of Kinshasa had been included in the study because of their expertise in the care of PLHIV and their accessibility after a random draw. Clinical data were recorded on worksheets previously tested by the study team. The parameters of interest for the present study were: the clinical state of the patient, the known medical history, and the previous morbidities. Results: 119 patients were included in this study. Sixty-seven patients, or 56.3%, are women, giving a sex ratio of 1.29 in favor of women. The mean age of the patients included is 39.87 ± 12.36 years. The most represented age group is that of 36 to 45 years with 37 patients (31.9%). The average temperature of the patients was 36.69°C ± 0.68°C. Forty-nine patients (41.5%) were in clinical stage 3; 55 patients (47.0%) had a normal clinical condition. The most common known medical histories are dental caries and sleep disorders (30.2%). The most common known prior morbidities are malaria (35.3%), high blood pressure and heart disease (14.7%). Conclusion: The most affected age group is that of 25 to 45 years. The majority of our patients begin treatment at WHO stage 3 with good clinical condition. Dental caries and sleep disorder (30.2%) are the most found medical history. Malaria (35.3%) is the most common previous morbidity.
Cite this paper
Booto, G. I. , Selenge, S. M. , Bongenya, B. I. , Ntumba, T. K. , Losenga, L. O. , Dikati, N. M. , Dembo, R. D. , Nonga, J. E. , Kabamba, C. A. , Kabengele, B. O. , Sombo, M. A. , Bumoko, G. M. and Kamangu, E. N. (2022). Clinical Profile of People Living with Human Immunodeficiency Virus Starting Treatment in Kinshasa, Democratic Republic of Congo. Open Access Library Journal, 9, e9134. doi: http://dx.doi.org/10.4236/oalib.1109134.
United Nations AIDS program (UNAIDS) (2020) Country Factsheets: Democratic Republic of the Congo.
https://www.unaids.org/en/regionscountries/countries/democraticrepublicofthecongo
Programme Nation de Lutte contre la VIH/SIDA et les ISTs, Ministère de la Santé Publique, République Démocratique du Congo (2016) Guide de prise en charge intégrée du VIH/SIDA en République Démocratique du Congo. Révision de Septembre 2016.
Kamangu, N.E., Bwiri, B.B. and Mvumbi, L.G. (2019) Clinical and Paraclinical Profile of People Living with Human Immunodeficiency Virus on Second Line Treatment in Kinshasa, Democratic Republic of Congo. Open Access Library Journal, 6, e5499. https://doi.org/10.4236/oalib.1105499
Mbula, M.M.K., Situakibanza, H.N.T., Mananga, L.G., Longokolo, M.M., Mandina, N.M., Mayasi, N.N., Mbula, M.M., Bepouka, B., Amaela, E.N., Tshilumba, D.N., Odio, O., Nkodila, A. and Longo Mbenza, B. (2020) Profil clinique et biologique des Personnes Vivant avec le VIH/SIDA suivies dans le Service des Maladies Infectieuses des Cliniques Universitaires de Kinshasa, République Démocratique du Congo. Revue Malienne d’Infectiologie et de Microbiologie, 15, 21-29.
https://doi.org/10.53597/remim.v15i2.1727
Losenga, L.O., Dikati, N.M., Bongenya, B.I., Ntumba, T.K., Booto, G.I., Dembo, R.D., Selenge, S.M., Nonga, J.E., Kabamba, C.A., Sombo, M.-T.A.S., Bumoko, G.M.M. and Kamangu, E.N. (2022) Sociodemographic and Anthropometric Profile of People Living with Human Immunodeficiency Virus Starting Treatment in Kinshasa, Democratic Republic of the Congo. Open Access Library Journal, 9, e9056.
https://doi.org/10.4236/oalib.1109056
Ministère du Plan et Suivi de la Mise en œuvre de la Révolution de la Modernité et Ministère de la Santé Publique, République Démocratique du Congo (2014) Enquête Démographique et de Santé 2013-2014 (EDS 2013-2014).
Kamangu, N.E., Bulanda, I.B., Bongenia, I.B., Botomwito, T.H., Mvumbi, L.G., De Mol, P., Vaira, D., Hayette, M.-P. and Kalala, L.R. (2015) Virological Profile of Patients Infected with HIV Starting Antiretroviral Treatment in Kinshasa. Open Access Library Journal, 2, e1564. https://doi.org/10.4236/oalib.1101564
Bulanda, B.I., Kateba, E.T., Bongenia, B.I., Kasongo, V.N., Kingombe, M.A. and Kamangu, E.N. (2018) Sociodemographic and Anthropometric Profile of Positive HIV Patients in Early Traditional Treatment: Case of the Bonkoko Center. Open Access Library Journal, 5, e4555. https://doi.org/10.4236/oalib.1104555
Buju, R.T., Akilimali, P.Z., Kamangu, E.N., Mesia, G.K., Kayembe, J.M.N. and Situakibanza, H.N. (2022) Predictors of Viral Non-Suppression among Patients Living with HIV under Dolutegravir in Bunia, Democratic Republic of Congo: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 19, Article 1085. https://doi.org/10.3390/ijerph19031085
Buju, R.T., Akilimali, P.Z., Kamangu, E.N., Mesia, G.K., Kayembe, J.M.N. and Situakibanza, H.N. (2022) Incidence and Predictors of Loss to Follow Up among Patients Living with HIV under Dolutegravir in Bunia, Democratic Republic of Congo: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 19, Article 4631. https://doi.org/10.3390/ijerph19084631
Desclaux, A. and Desgrées du Lou, A. (2006) Les Femmes Africaines face à l’épidémie du SIDA. Population et Sociétés, 428, 1-4.
https://doi.org/10.3917/popsoc.428.0001
Programme conjoint des Nations Unies sur le VIH/SIDA (ONUSIDA) (2019) Les Communautés concernées: La Réponse au VIH en Afrique Occidentale et Centrale. Mise à Jour Mondiale sur le SIDA en 2019.
https://www.unaids.org/sites/default/files/media_asset/2019_global-aids-report_western-and-central-africa_fr.pdf
Kamangu, N.E., Wumba, R.D.M., Situakibanza, H.N.T., Lukusa, P.T., Kapend, L.K., Mvumbi, G.L., Hayette, M.P. and Kalala, R.L. (2018) Molecular Epidemiology of Human Immunodeficiency Virus Type 1 and Therapeutic Monitoring of Patients Treated in Kinshasa/Democratic Republic of the Congo. International Journal of HIV and AIDS Research, 1, 6-11.
Situakibanza NH, Kapita MB, Mbendi N, Odio W, Mbula M, Muvova D, Mizerero D, Izzia K. (1996) Etiologie de la fièvre au cours du SIDA: A propos de 64 cas. Panorama Médicale, 1, 842-5
Mussa, R.M., Nkodila, A.N., Kiala, N.A., Muilu, J.M. and Mananga, G.L. (2021) Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-Sectional Study. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 7, 61-65.
https://doi.org/10.11648/j.ijhpebs.20210702.12
Kamangu, E.N., Muhindo, H.M., Wapa-Kamangu, C.W. and Situakibanza, H.N.T. (2015) Prevalence of Malaria Infection among People Living with HIV in Kinshasa. Open Access Library Journal, 2, e1077. https://doi.org/10.4236/oalib.1101077