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Quality of Life and Associated Factors in Patients Infected with Hepatitis B and C Virus in a Moroccan Region: A Cross-Sectional Study

DOI: 10.4236/oalib.1108781, PP. 1-13

Subject Areas: Public Health, Gastroenterology & Hepatology, Psychiatry & Psychology, Epidemiology

Keywords: Quality of Life, Chronic Hepatitis, Hepatitis B Virus, Hepatitis C Virus, SF12, Health-Related Quality of Life, Morocco

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Introduction: Hepatitis B or C virus infection is one of the most common liver infections leading to altered health-related quality of life (HRQoL) in patients. The goal of this study was to assess the quality of life of patients infected with hepatitis B or C virus and to determine the factors that might be associated with worse outcomes. Methods: A cross-sectional study was conducted in patients aged 18 years and over followed on an outpatient basis at the teaching hospital Hassan II in Fez for hepatitis B or C. These patients were asked to complete the SF-12 questionnaire file which is the short form of the quality measurement scale of life SF-36. Sociodemographic, clinical and economic information was collected. A descriptive analysis was carried out, then a univariate analysis in search of factors associated with quality of life, and finally a multivariate analysis by linear regression was carried out adjusting for possible confounding factors. Results: A total of 94 patients whose mean age was 55.69 ± 13.25 years met the inclusion criteria. The physical quality of life was altered with an average of 41.98 ± 12.67. Hepatitis C virus infection (β = -6.802; 95% CI = (-12.05; -1.55)), cirrhosis (β = -6.947, 95% CI = (-12.04; -1.84)) and lack of employment (β = -8.48, 95% CI = (-13.18; -3.77)) were the factors associated with poor quality of life. The mental quality of life (MCS) was also altered with an average of 46.32 ± 12.84. In multivariate analysis we found that participants with hepatitis C (β = 7.444, 95% CI = (2.14; 12.74)), unemployed (β = 6.697, 95% CI (2.28; 11.11)) and having received treatment (β = 8.295, 95% CI (2.95; 13.63) had a better mental quality of life, while alcoholics had an impaired mental quality of life (β = -8.105, 95% CI (-15.28; -0.92)). Conclusion: Quality of life is altered in patients with chronic hepatitis regardless of type.

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Jho, D. B. , Hakima, A. , Harch, I. E. , Benmaamar, S. , Hind, B. , Nassiba, B. , Saliou, B. M. , Passy, C. , Otmani, N. , Abkari, M. E. , Berraho, M. A. , Tachfouti, N. and Fakir, S. E. (2022). Quality of Life and Associated Factors in Patients Infected with Hepatitis B and C Virus in a Moroccan Region: A Cross-Sectional Study. Open Access Library Journal, 9, e8781. doi:


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