全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

Biotechnology Application of Therapeutic Antibody Drug Discovery and Preparation

DOI: 10.4236/oalib.1107719, PP. 1-6

Subject Areas: Biotechnology

Keywords: Therapeutic Monoclonal Antibodies, Antibody Engineering, Targeted, ADC

Full-Text   Cite this paper   Add to My Lib

Abstract

According to the technical application, therapeutic mechanism and application prospect of therapeutic antibodies are discussed from the research and development of therapeutic antibodies to their application technology. Also, following is a list of some disadvantages of the drug. May this article shall lead perspective in the next section.

Cite this paper

Cao, H. (2021). Biotechnology Application of Therapeutic Antibody Drug Discovery and Preparation. Open Access Library Journal, 8, e7719. doi: http://dx.doi.org/10.4236/oalib.1107719.

References

[1]  刘宗超, 李哲轩, 张阳, 周彤, 张婧莹, 游伟程, 潘凯枫, 李文庆. 2020全球癌症统计报告解读[J]. 肿瘤综合治疗电子杂志, 2021, 7(2): 1-14.
[2]  梁琍. 治疗性抗体的研究进展[J]. 生物技术通讯, 2006(5): 799-802.
[3]  Vergote, I., Dean, E., Lassen, U., de Bono, J., Drew, Y., Machiels, J.-P., Nielsen, D., Arkenau, H.-T., Forster, M., Jones, R., Slomovitz, B., Spicer, J., Johnson, M., Cornez, N., Gennigens, C., Fulton, B., Lisby, S., Basse, L., Coleman, R. and Hong, D.S. (2017) A Phase IIa Study of Tisotumab Vedotin (HuMax®-TF-ADC) in Patients with Relapsed, Recurrent and/or Metastatic Cervical Cancer. Annals of Oncology, 28, V330-V331. https://doi.org/10.1093/annonc/mdx372.001
[4]  Nguyen Ngan, T.B., Lin, J., Tay, S.J., Mariati, Y.J., NguyenKhuong, T. and Yang, Y.S. (2021) Multiplexed Engineering Glycosyltransferase Genes in CHO Cells via Targeted Integration for Producing Antibodies with Diverse Complex-Type N-glycans. Scientific Reports, 11, Article No. 12969. https://doi.org/10.1038/s41598-021-92320-x
[5]  T·C-C·国, J·F·查帕罗里格斯, W·陈, A·S-R·陈, E·D·帕斯夸, T·J·范布拉尔科, L·M·布斯塔尼, W·胡, Y·A·杨, P·施特罗普, A·拉吉帕尔. 治疗性抗体和它们的用途[P]. 美国, CN108136002A. 2018-06-08.
[6]  刘昌孝. 抗体药物的药理学与治疗学研究[M]. 北京: 科学出版社, 2015.
[7]  张峰. 抗体药物部分Fc效应功能评价研究[C]//中国药学会. 2016年生物技术药物理化特性分析与质量研究技术研讨会资料汇编. 北京: 中国药学会, 2016: 1.
[8]  He, K.F., Zeng, S. and Qian, L.H. (2020) Recent Progress in the Molecular Imaging of Therapeutic Monoclonal Antibodies. Journal of Pharmaceutical Analysis, 10, 397- 413. https://doi.org/10.1016/j.jpha.2020.07.006
[9]  E·哈洛, D·莱恩. 抗体技术实验指南[M]. 沈关心, 龚非力, 译. 北京: 科学出版社, 2002.
[10]  于天维, 肖翌, 田海军, 潘琦, 陈应华. Purification of Murine Monoclonal IgM Antibody [J]. Tsinghua Science and Technology, 1999(3): 1532-1534.
[11]  Zhu, Z.P. and Yan, L. (2011) Next Generation of Antibody Therapy for Cancer. Chinese Journal of Cancer, 30, 293-302. https://doi.org/10.5732/cjc.011.10123
[12]  高倩, 江洪, 叶茂, 郭文娟. 全球单克隆抗体药物研发现状及发展趋势[J]. 中国生物工程杂志, 2019, 39(3): 111-119.
[13]  国家卫生健康委员会. 新型抗肿瘤药物临床应用指导原则(2019年版) [J]. 肿瘤综合治疗电子杂志, 2020, 6(1): 16-47.
[14]  谭显海, 程子宇, 董陶明. 曲妥珠单抗联合化疗序贯放疗对乳腺癌术后患者心电图异常率的影响[J]. 当代医学, 2021, 27(19): 161-163.
[15]  Sjöberg, R., Mattsson, C., Andersson, E., Hellström, C., Uhlen, M., Schwenk, J.M., Ayoglu, B. and Nilsson, P. (2016) Exploration of High-Density Protein Microarrays for Antibody Validation and Autoimmunity Profiling. New Biotechnology, 33, 582- 592. https://doi.org/10.1016/j.nbt.2015.09.002

Full-Text


comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133

WeChat 1538708413