All Title Author
Keywords Abstract

Publish in OALib Journal
ISSN: 2333-9721
APC: Only $99

ViewsDownloads

Exceptional Localization of a Prolactinoma as Part of Familial Isolated Pituitary Adenomas

DOI: 10.4236/oalib.1107229, PP. 1-4

Subject Areas: Diabetes & Endocrinology

Keywords: Familial Isolated Pituitary Adenomas, Prolactinoma, Pituitary Stalk

Full-Text   Cite this paper   Add to My Lib

Abstract

The syndrome of familial isolated pituitary adenomas (FIPA) or predisposition to pituitary adenomas (PAP) is characterized by the presence within the same family of at least two isolated pituitary adenomas without any other type of associated endocrine tumor. These pituitary tumors may present as homogenous with the same tumor phenotype or heterogeneous with different patterns of pituitary tumor phenotypes (GH, Prolactine, ACTH secretion or non-functioning pituitary adenomas) within the same kindred. Patients with FIPA are significantly younger at diagnosis and have significantly larger pituitary adenomas than matched sporadic pituitary adenoma counterparts. We report the case of a prolactinoma attached to the pituitary stalk as part of FIPA, revealed by erectile dysfunction.

Cite this paper

Asbar, H. , Benlafqih, M. , Askaoui, S. , Rafi, S. , Mghari, G. E. and Ansari, N. E. (2021). Exceptional Localization of a Prolactinoma as Part of Familial Isolated Pituitary Adenomas. Open Access Library Journal, 8, e7229. doi: http://dx.doi.org/10.4236/oalib.1107229.

References

[1]  Beckers, A., Aaltonen, L.A., Daly, A.F. and Karhu, A. (2013) Familial Isolated Pituitary Adenomas (FIPA) and the Pituitary Adenoma Predisposition due to Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene. Endocrine Reviews, 34, 239-277. https://doi.org/10.1210/er.2012-1013
[2]  Tichomirowa, M.A., Daly, A.F. and Beckers, A. (2009) Familial Pituitary Adenomas. Journal of Internal Medicine, 266, 5-18. https://doi.org/10.1111/j.1365-2796.2009.02109.x
[3]  Daly, A.F., Jaffrain-Rea, M.L., Ciccarelli, A., Valdes-Socin, H., Rohmer, V., Tamburrano, G., et al. (2006) Clinical Characterization of Familial Isolated Pituitary Adenomas. The Journal of Clinical Endocrinology & Metabolism, 91, 3316-3323. https://doi.org/10.1210/jc.2005-2671
[4]  Daly, A.F., Petrossians, P. and Beckers, A. (2005) An Overview of the Epidemiology and Genetics of Acromegaly. Journal of Endocrinological Investigation, 28, 67-69.
[5]  Beckers, A. and Daly, A.F. (2007) The Clinical, Pathological, and Genetic Features of Familial Isolated Pituitary Adenomas. European Journal of Endocrinology, 157, 371-382. https://doi.org/10.1530/EJE-07-0348
[6]  Vierimaa, O., Georgitsi, M., Lehtonen, R., Vahteristo, P., Kokko, A., Raitila, A., et al. (2006) Pituitary Adenoma Predisposition Caused by Germline Mutations in the AIP Gene. Science, 312, 1228-1230. https://doi.org/10.1126/science.1126100
[7]  Daly, A.F. and Beckers, A. (2015) Familial Isolated Pituitary Adenomas (FIPA) and Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene. Endocrinology and Metabolism Clinics, 44, 19-25. https://doi.org/10.1016/j.ecl.2014.10.002

Full-Text


comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

微信:OALib Journal