Objective: To investigate the relationship between the four blood coagulation items and blood glucose and blood lipids in stroke patients with type 2 diabetes. Methods: According to whether they had type 2 diabetes, 134 stroke patients were divided into the observation group (n = 62) with stroke and type 2 diabetes and the control group without type 2 diabetes (n = 72), and the blood coagulation of each group was compared. Results: There was no significant difference in the four coagulation items between the two groups of patients, and hyperglycemia did not seem to have a significant effect on this. Conclusion: The coagulation changes in stroke patients may be greatly affected by the acute onset of stroke, and the impact of type 2 diabetes may be chronic and insignificant.
Cite this paper
Wang, Y. and Liang, X. (2020). Correlation Analysis of Four Blood Coagulation Items with Blood Lipids and Blood Glucose in Stroke Patients with Type 2 Diabetes. Open Access Library Journal, 7, e7042. doi: http://dx.doi.org/10.4236/oalib.1107042.
Hu, X.L. and Wang, Z.K. (2009) Correlation Analysis on Blood Glucose, Renal Function and Blood Gas Related Markors in Severe Trauma Patients. Modern Diagnosis & Treatment, 20, 270-272.
Zheng, T., Xiao, C., He, J., et al. (2002) Study on the Coagulation Changes in Type 2 Diabetes Patients. Chinese Journal of Laboratory Medicine, 25, 290-292.
Lv, Z.G. and Tang, Q. (2002) Changes of Plasma Coagulation Parameters in Aged NIDDM Patients. Journal of Jiangsu University (Medicine Edition), 12, 252-253.
Lin, G.L., Huang, L.F., Qiu, S.B., et al. (2005) Coagulation Disturbance in Patients with Type 2 Diabetes Mellitus. Chinese Journal of Hemorheology, 15, 86-87, 94.
Ahmed, M., Chowdhury, N.A., Sofdar, G., et al. (2014) High Fibrinogen Level Is an Independent Predictor of Presence and Severity of Coronary Artery Disease. Cardiovascular Journal, 7, 4-10. https://doi.org/10.3329/cardio.v7i1.20784
Chen, Y.N., Sun, L. and Zheng, J.H. (2004) Correlation of Prognosis with the Changes of Blood Glucose and Blood Lipid and Blood Coagulation in Patients with Cerebral Hemorrhage. Chinese Journal of Clinical Rehabilitation, 8, 4512-4513.
Lane, D.A., Wolff, S., Ireland, H., et al. (1983) Activation of Coagulation and Fibrinolytic Systems Following Stroke. British Journal of Haematology, 53, 655-658.
https://doi.org/10.1111/j.1365-2141.1983.tb07316.x
Catto, A.J. and Grant, P.J. (1995) Risk Factors for Cerebrovascular Disease and the Role of Coagulation and Fibrinolysis. Blood Coagulation & Fibrinolysis, 6, 497-510.
https://doi.org/10.1097/00001721-199509000-00001
Gentile, N.T., Vaidyula, V.R., Kanamalla, U., et al. (2007) Factor VIIa and Tissue Factor Procoagulant Activity in Diabetes Mellitus after Acute Ischemic Stroke: Impact of Hyperglycemia. Thrombosis and Haemostasis, 98, 1007-1013.
https://doi.org/10.1160/TH06-12-0719
Zhou, J., Liu, N., Gu, Q.Y., et al. (2011) Levels and Clinical Significance of Serum Tissue Factor and Tissue Factor Pathway Inhibitor in Diabetic Stroke. Journal of Apoplexy and Nervous Diseases, 28, 420-422.