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Antibiotic Resistance: An Investigation on Effectiveness of Antibiotics Treatment on Bacterial Growth

DOI: 10.4236/oalib.1106347, PP. 1-17

Subject Areas: Microbiology

Keywords: Antibiotic, Resistance, Infection & Treatment, Erythromycin, Cephalexin, Chloramphenicol

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Background: The proclivity of bacteria resistance to antibiotics has led researchers to develop more interest in antibiotics efficiency in tackling bacterial infections. As part of the effort to finding final resolutions to antibiotics effectiveness, this study was conducted to ascertain the antibiotic sensitivity pattern of three bacterial strains, this study was carried out from March 2019 to June 2019, using different antibiotics such as Ampicillin (AMP), Tetracycline (TET), Erythromycin (ERY), Chloramphenicol (C) Cephalexin (CN), Doxycycline (DO) and Streptomycin (STR) on E. coli, Staphylococcus albus and Bacillus megaterium as part of a project. The potential antagonistic effects were observed in all the antibiotics but with different effects on bacteria strains. Some of the antibiotics were very effective in some bacterial strains and others were less effective. The results obtained evidence that tetracycline has more effects on E. coli and Bacillus meg, but less effective on Staphylococcus. The most effective antibiotic for E. coli was chloramphenicol while the least effective was erythromycin. For Staphylococcus albus, the investigation result found Cephalexin to be more effective, while the least effective was ampicillin. However, Doxycycline also appeared to be more effective on Bacillus megaterium compared to chloramphenicol.

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Akinyemi, O. M. (2020). Antibiotic Resistance: An Investigation on Effectiveness of Antibiotics Treatment on Bacterial Growth. Open Access Library Journal, 7, e6347. doi:


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