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Voriconazole Induced Periostitis in a Patient with ANCA Vasculitis: A Case Report

DOI: 10.4236/oalib.1105789, PP. 1-6

Subject Areas: Rheumatology

Keywords: Vasculitis, Voriconazole, Periostitis

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Abstract

A 62 year-old gentleman with underlying ANCA vasculitis was admitted to hospital for severe musculoskeletal pain involving both shoulders, hips and hands. There was a history of long term usage of anti-fungal medica-tion-voriconazole for his Aspergillus fumigatus lung infection as treatment and prophylaxis. Clinically the range of movement of both shoulders and hips was restricted with the presence of digital swelling of both hands. His imaging findings noted the presence of periosteal reaction involving shoulders and hips in addition to increased radiotracer uptake on his bone scan. A diagnosis of voriconazole induced periostitis was made and dis-continuation of therapy led to rapid clinical improvement.

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Bajwa, H. , Ng, C. , Abdullah, A. , Aslam, S. and O’Connell, P. (2019). Voriconazole Induced Periostitis in a Patient with ANCA Vasculitis: A Case Report. Open Access Library Journal, 6, e5789. doi: http://dx.doi.org/10.4236/oalib.1105789.

References

[1]  Scott, L.J., et al. (2007) Drugs. Voriconazole: A Review of Its Use in the Management of Invasive Fungal Infections.
[2]  Tai-lor, T.D. and Richardson, M.L. (2015) Case 215, Voriconazole-Induced Periostitis. Radiology, 274, 930-935.
[3]  Wang, T.F., Wang, T., Altman, R., Eshaghian, P., Lynch, J.P., Ross, D.J., Belperio, J.A., Weigt, S.S., Saggar, R., Gregson, A., Kubak, B. and Saggar, R. (2009) Periostitis Secondary to Prolonged Voriconazole Therapy in Lung Transplant Recipients. American Journal of Transplantation, 9, 2845-2850.
https://doi.org/10.1111/j.1600-6143.2009.02837.x
[4]  Chen, L. and Mulligan, M.E. (2011) Medication-Induced Periostitis in Lung Transplant Patients: Periostitis Deformans Revisited. Skeletal Radiology, 40, 143-148.
https://doi.org/10.1007/s00256-010-0997-y
[5]  Lustenberger, D.P., Granata, J.D. and Scharschmidt, T.J. (2011) Periostitis Secondary to Prolonged Voriconazole Therapy in a Lung Transplant Recipient. Orthopedics, 34, e793-e796. https://doi.org/10.3928/01477447-20110922-35
[6]  Gerber, B., Guggenberger, R., Fasler, D., et al. (2012) Reversible Skeletal Disease and High Fluoride Serum Levels in Hematologic Patients Receiving Voriconazole. Blood, 120, 2390-2394. https://doi.org/10.1182/blood-2012-01-403030
[7]  Lindsay, R. (1990) Fluoride and Bone-Quantity versus Quality. New England Journal of Medicine, 322, 845-846. https://doi.org/10.1056/NEJM199003223221210
[8]  Hirota, K., Yasoda, A., Fujii, T. and Inagaki, N. (2014) Voriconazole-Induced Periostitis in a Patient with Overlap Syndromes. BMJ Case Reports, 2014, bcr2013203485.
https://doi.org/10.1136/bcr-2013-203485

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