Introduction: Post-stroke depression occurs in a context of stroke characterized by sadness, loss of interest, feelings of guilt, loss of appetite, a feeling of tiredness, and a lack of concentration. Material and Methods: We conducted a descriptive cross-sectional study from January 1, 2013 to September 30, 2016. For the diagnosis of post-stroke depression, neuropsychological tests (DSM-IV and MADRS) were used. The collection approach was a maintenance survey followed by an examination. Results: From 153 stroke patients, 48.4% (n = 74) had post-stroke depression. Depressed mood was noted in 50.3% and 43.8% had a marked decrease in interest. 67.9% of these patients had a primary level of education. Widows had 4.2 times the risk of post-stroke depression, and married and retired patients were 3 times more likely than public servants. The occurrence of post-stroke depression was significantly related to the presence of motor deficit in our patients, p < 0.0001. Conclusion: These results suggest that the risk of developing depression after stroke increases with the motor deficit. The DSM-IV and MADRS scores remain neuropsychological examinations of choice for the diagnostic approach.
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Camara, I. A. , Coulibaly, C. M. , Mbourou, N. D. , Gnigone, P. M. , Matsalou, G. A. G. M. , Mandzela, A. N. , Oura, L. , Mapaga, J. N. , Kombila, U. D. , Moubecka, M. M. and Kouna, P. N. (2018). Post-Stroke Depression at Teaching Hospital Center of Libreville. Open Access Library Journal, 5, e5049. doi: http://dx.doi.org/10.4236/oalib.1105049.
Ryck, A., Fransen, E., Brouns, R., et al. (2014) Post Stroke Depression and Its Multifactorial Nature: Results from a Prospective Longitudinal Study. Journal of the Neurological Sciences, 347, 159-166. https://doi.org/10.1016/j.jns.2014.09.038
Mbelesso, P., Senekian, V.P., Yangatimbi, E., et al. (2014) Post Stroke Depression in Africa: Myth or Reality. Bulletin de la Société de Pathologie Exotique, 107, 350-355. https://doi.org/10.1007/s13149-014-0399-9
Kouna Ndouongo, P., Millogo, A., Siemofo Kangang, F.D.P. and Assengone-Zeh, Y. (2007) Epidemiological and Evolutionary Aspects of Stroke at the Hospital Center of Libreville (Gabon). AJNS, 12-17.
Paolucci, S., Gandolfo, C., Provinciali, L., et al. (2005) Quantification of the Risk of Post-Stroke Depression: The Italian Multicenter Study DESTRO. Acta Psychiatrica Scandinavica, 112, 272-278. https://doi.org/10.1111/j.1600-0447.2005.00590.x
Mapoure, Y.N., Kuate, C., Tchaleu, C.B., et al. (2014) Stroke Epidemiology in Douala: Three Years Prospective Study in a Teaching Hospital in Cameroon. World Journal of Neuroscience, 4, 406-414. https://doi.org/10.4236/wjns.2014.45044
Sagui, E., M’baye, P.S., Dubecq, C., et al. (2005) Ischemic and Hemorrhagic Strokes in Dakar, Senegal. Stroke, 36, 1844-1847. https://doi.org/10.1161/01.STR.0000177864.08516.47
Mpembi Nkosi, M., Mampunza Ma Miezi, S., Massamba Kubuta, V., et al. (2014) Clinical Evolution of Post-Stroke Stroke Depression in Kinshasa. Neurological Review, 170, 614-620.
Glamcevski II, M.T. and Pierson, J. (2005) Prevalence of and Associated Factors with Post Stroke Depression: A Malaysian Study. Journal of Stroke and Cerebrovascular Diseases, 14, 157-161. https://doi.org/10.1016/j.jstrokecerebrovasdis.2005.03.006
Oladiji, J.O., Akinbo, S.R., Aina, O.F. and Aiyejusunle, C.B. (2009) Risk Factors of Post-Stroke Depression among Stroke Survivors in Lagos, Nigeria. African Journal of Psychiatry, 12, 47-51. https://doi.org/10.4314/ajpsy.v12i1.30278
Imarhiagbe, F.A. and Owolabi, A. (2015) Post Stroke Depression in a Sub Saharan Africans: Validation of the Japanese Stroke Scale for Depression. Sahel Medical Journal, 18, 121-125. https://doi.org/10.4103/1118-8561.169285
Ojagbemi, A., Owolabi, M., Atalabi, M. and Baiyewu, O. (2013) Stroke Lesions and Post Stroke Depression among Survivors in Ibadan, Nigeria. African Journal of Medicine and Medical Sciences, 42, 245-251.
Zhang, W.-N., Pan, Y.-H., Wang, X.-Y. and Zhao, Y. (2013) A Prospective Study of the Incidence and Correlated Factors of Post-Stroke Depression in China. PLoS ONE, 8, 78-81. https://doi.org/10.1371/journal.pone.0078981
Alajbegovic, A., Djelilovic-Vranic, J., Alajbegovic, S., Nakicevic, A. and Todorovic, L. (2014) Tiric-Campara Post Stroke Depression. Medical Archives, 68, 47-50. https://doi.org/10.5455/medarh.2014.68.47-50
Cole, M. and Dendukuri, N. (2003) Risk Factors for Depression in Elderly Subjects: A Systematic Review and Meta-Analysis. American Journal of Psychiatry, 160, 1147-1156. https://doi.org/10.1176/appi.ajp.160.6.1147
Poynter, B., Shuman, M., Diaz-Granados, N., Kapral, M., Grace, S.L. and Stewart, D.E. (2009) Sex Differences in the Prevalence of Post-Stroke Depression: A Systematic Review. Psychosomatics, 50, 563-569. https://doi.org/10.1016/S0033-3182(09)70857-6
Sienkiewicz-Jarosz, H., Milewska, D., Bochyńska, A., et al. (2010) Predictors of Depressive Symptoms in Patients with Stroke—A Three-Month Follow-Up. Neurologia i Neurochirurgia POLSKA, 44, 113-120. https://doi.org/10.1016/S0028-3843(14)60402-3
Zhang, Y., Cheng, L., Chen, Y., Yang, G.Y., Liu, J. and Zeng, L. (2016) Clinical Predictor and Circulating microRNA Profile Expression in Patients with Early Onset Post-Stroke Depression. Journal of Affective Disorders, 193, 51-58. https://doi.org/10.1016/j.jad.2015.12.061
Ngateu Bang, G.T. (2015) Predictors of Mental Depression after a Cerebral Vascular Accident in Yaounde. Doctoral Thesis in Medicine, Faculty of Medicine and Biomedical Sciences, Yaoundé I.
Yue, Y., Rui, L., Lu, J., et al. (2015) Reliability and Validity of a New Post-Stroke Depression in Chinese Population. Journal of Affective Disorders, 174, 317-323. https://doi.org/10.1016/j.jad.2014.11.031
Akinyemi, R.O., Allan, L., Owolabi, M.O., et al. (2014) Profile and Determinants of Vascular Cognitive Impairment in African Stroke Survivors: The CogFAST Nigeria Study. Journal of the Neurological Sciences, 346, 241-249. https://doi.org/10.1016/j.jns.2014.08.042
NdzanaTsanga, J.B. (2013) Mental Depression in People with a Cerebral Vascular Accident Followed at Central Hospital of Yaoundé. PhD Thesis in Medicine, Faculty of Medicine and Biomedical Sciences, Yaoundé I.
Cheng, S.Y., Zhao, Y.D., Li, J., Chen, X.Y., Wang, R.D. and Zeng, J.W. (2014) Plasma Levels of Glutamate during Stroke Is Associated with Development of Post-Stroke Depression. Psychoneuroendocrinology, 47, 126-135. https://doi.org/10.1016/j.psyneuen.2014.05.006
Man-van Ginkel, J.M., Hafsteinsdottir, T.B., Lindeman, E., Ettema, R.G., Grobbee, D.E. and Schuurmans, M.J. (2013) In-Hospital Risk Prediction for Post-Stress Depression: Development and Validation of the Post-Stroke Depression Prediction Scale. Stroke, 44, 2441-2445. https://doi.org/10.1161/STROKEAHA.111.000304
De Ryck, A., Brouns, R., Geurden, M., Elseviers, M., De Deyn, P.P. and Engelborghs, S. (2014) Risk Factors for Post Stroke Depression: Identification of Inconsistencies Based on a Systematic Review. Journal of Geriatric Psychiatry and Neurology, 27, 147-158. https://doi.org/10.1177/0891988714527514
Vibo, R., Korv, J. and Roose, M. (2007) One-Year out after First-Ever Stroke According to Stroke Subtype, Severity, Risk Factors and Pre-Stroke Treatment. A Population-Based Study from Tartu, Estonia. European Journal of Neurology, 14, 435-439. https://doi.org/10.1111/j.1468-1331.2007.01704.x
Hackett, M.L. and Anderson, C.S. (2005) Predictors of Depression after Stroke: A Systematic Review of Observational Studies. Stroke, 36, 2296-2301. https://doi.org/10.1161/01.STR.0000183622.75135.a4
Johnson, J.L., Minarik, P.A., Nystrom, K.V., Bautista, C. and Gorman, M.J. (2006) Post Stroke Depression and Risk Factors: An Integrative Literature Review. Journal of Neuroscience Nursing, 38, 316-327. https://doi.org/10.1097/01376517-200609000-00008
Mpembi, M.N., Mampunza ma Miezi, S., Peeters, A., et al. (2013) Sociodemographic Profile and Social Support for Post-Stroke Depression in Kinshasa: A Rehabilitation Based Cross-Sectional Study. Open Journal of Epidemiology, 3, 111-117. https://doi.org/10.4236/ojepi.2013.3318