Rich., originally from Cuba and known as “Contraguao”, has traditionally been
used to counteract quickly and effectively burns produced by Comocladia dentate Jacq (Guao), vegetable
species that secretes a highly caustic latex for skin and mucous membranes. A
burn is a traumatic injury resulting in local and systemic injury with
oxidative changes; in this sense the antioxidants play an important role. In order to offer
aspects related to the quality and effectiveness of the plant, its pharmacognostic,
phytochemical and antioxidant activity is presented. The morphoanatomical
evaluation was carried out, physical-chemical parameters were determined for
the crude drug and for the aqueous extract. The chemical profile of the extract was estimated by thin layer chromatography,
ultraviolet-visible and quantification of total phenols by Folin-Ciocalteu and
total flavonoids by the colorimetric method of aluminum trichloride (AlCl3).
Finally, the antioxidant activity was tested by the FRAP and DPPH techniques.
Through the pharmacognostic study, the quality specifications of the drug and
the extract were established. The methods of analysis used for the chemical
profile suggested the presence of flavonoids and phenols in general. The
aqueous extract showed antioxidant properties by the two methods evaluated. The
study of G. calyptrata provided
pharmacognostic, phytochemical and effectiveness as an antioxidant evidence,
aspects to consider in the possible use of the plant by our Natural and
Cite this paper
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