Objective: The aim of
this study was to examine the effects of high-intensity intermittent exercise
(HIIE) on features of immunometabolism by comparing elderly female sarcopenia
and non-sarcopenia in elderly female patients with type 2 diabetes (T2MD).
Differences in metabolism and inflammatory responses between the two groups
were compared. Methods: 6 elderly female sarcopenia patients with T2MD served
as sarcopenia group, and 7 elderly female non-sarcopenia patients with T2MD
served as control subjects. Using dual energy X-ray absorptiometry (DXA) to the
subjects’ body fat compositions was measured. All subjects underwent three
high-intensity Wingate tests at 5-minute intervals, and peak and average power
during each Wingate trial were recorded. Blood samples were collected
immediately after the test was completed. Peripheral blood levels of the
inflammatory cytokine IL-6, which is related to mitosis, were measured in both
groups before and after HIIE by ELISA. Results: The non-sarcopenia group had a
higher metabolic rate than the sarcopenia group. Sarcopenia had no significant
effect on the differences in the IL-6 inflammatory response (p = 0.430).
Conclusion: The metabolic energy and rate during HIIE differed between the two
groups. Non-sarcopenia group exhibited higher metabolic levels. No significant
difference between groups was observed in the IL-6 inflammatory response during
HIIE.
Cite this paper
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